Aoki Hiromasa

アオキヒロマサ | Aoki Hiromasa

Affiliation and department：
Job title：助教

Research field (4)： Fetal medicine/Pediatrics , Tumor biology , Cell biology , Clinical pharmacy

Research keywords (11)：小児がん , 神経芽腫 , 腫瘍免疫 , マクロファージ , NK細胞 , エピジェネティクス , 細胞周期 , 分化誘導 , iPS細胞 , 血液脳関門 , 血管内皮細胞

Research theme for competitive and other funds (10)：

2023 - 2026 神経芽腫のNK細胞からの免疫逃避メカニズム解明とがん免疫療法への応用
2024 - 2026 癌細胞超選択的集積性を有した光感受性薬剤による次世代PDTの開発
2024 - 2025 次世代光感受性物質の開発
2022 - 2025 Brain hypothermia focusing on erythropoietin and microglial activation control
2022 - 2024 DNAメチル化状態に着目した神経芽腫に対する新規治療法の創出

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Papers (29)：

Naoko Inamura, Taeko Kawai, Takashi Watanabe, Hiromasa Aoki, Mineyoshi Aoyama, Atsuo Nakayama, Junko Matsuda, Yasushi Enokido. Promyelinating drugs ameliorate oligodendrocyte pathologies in a mouse model of Krabbe disease. Molecular Genetics and Metabolism. 2024. 108497-108497
Satoru Takeshita, Hiroki Kakita, Nami Nakamura, Mari Mori, Kohki Toriuchi, Hiromasa Aoki, Yasumichi Inoue, Hidetoshi Hayashi, Yasumasa Yamada, Mineyoshi Aoyama. Thrombopoietin exerts a neuroprotective effect by inhibiting the suppression of neuronal proliferation and axonal outgrowth in intrauterine growth restriction rats. Experimental neurology. 2024. 114781-114781
Tomoki Okada, Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Hiroshi Takase, Shigeru Ohshima, Teruaki Sugino, Rei Unno, Kazumi Taguchi, et al. Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophages. Urolithiasis. 2024. 52. 1
Mai Nagasaka, Chiharu Miyajima, Yasumichi Inoue, Sakura Hashiguchi, Yuya Suzuki, Daisuke Morishita, Hiromasa Aoki, Kohki Toriuchi, Ryohei Katayama, Mineyoshi Aoyama, et al. ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis. Biochemical and Biophysical Research Communications. 2024
Naoya Fukuda, Kohki Toriuchi, Rina Mimoto, Hiromasa Aoki, Hiroki Kakita, Yoshiaki Suzuki, Satoru Takeshita, Tetsuya Tamura, Hisao Yamamura, Yasumichi Inoue, et al. Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4. Neurochemical Research. 2023

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MISC (8)：

Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Hiroshi Takase, Shigeru Ohshima, Rika Banno, Kazumi Taguchi, Tadahiro Hashita, Tamihide Matsunaga, et al. M2 MACROPHAGES DIFFERENTIATED FROM IPS CELLS HAVE HIGHER ABILITIES TO PHAGOCYTOSE AND PROCESS CALCIUM OXALATE CRYSTALS THAN SIMILARLY INDUCED M1 MACROPHAGES. JOURNAL OF UROLOGY. 2020. 203. E82-E83
松永民秀, 松永民秀, 中山瑞希, 山下美紗季, 青木啓将, 坡下真大, 坡下真大, 岩尾岳洋, 岩尾岳洋. ヒトiPS細胞より嚢状構造物を経由した血管内皮前駆細胞の作出. HAB研究機構学術年会プログラム・要旨集. 2020. 27th
中山瑞希, 青木啓将, 山下美紗季, 坡下真大, 坡下真大, 松永民秀, 松永民秀. iPS-sac由来血管内皮細胞前駆細胞の作出. Journal of Toxicological Sciences. 2019. 44. Supplement. S255-S255
Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Hiroshi Takase, Kazumi Taguchi, Tadahiro Hashita, Tamihide Matsunaga, Kenjiro Kohri, Takahiro Yasui. IMPACT OF NEW DRUG SCREENING MODEL USING INDUCED PLURIPOTENT STEM CELL-DERIVED MACROPHAGES TO PHAGOCYTOSE CALCIUM OXALATE CRYSTALS FOR PREVENTION OF URINARY STONES. JOURNAL OF UROLOGY. 2019. 201. 4. E672-E672
岡田淳志, 青木啓将, 小野里太智, 加藤大貴, 高瀬弘嗣, 田口和己, 坡下真大, 松永民秀, 郡健二郎, 安井孝周. iPS細胞由来マクロファージを用いたシュウ酸カルシウム結晶貪食スクリーニングモデルの確立. 日本泌尿器科学会総会(Web). 2019. 107th

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Patents (3)：

血管内皮前駆細胞の調製方法
ヒトiPS細胞由来脳毛細血管内皮前駆細胞から脳毛細血管内皮細胞への分化誘導方法
血管内皮前駆細胞の調製及び拡大培養

Books (1)：

低酸素性虚血性脳症への低体温脳保護療法
2022

Education (2)：

2016 - 2020 Nagoya City University
2014 - 2016 愛知県がんセンター研究所腫瘍制御学分野

Professional career (1)：

博士 (薬学) (名古屋市立大学大学院薬学研究科)

Work history (1)：

2020/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Pathobiology Assistant Professor

Committee career (1)：

2021/04 - 現在 Nagoya City University ALlied Medical Education Committee (AMEC) committee member

Association Membership(s) (3)：

日本癌学会 , 日本薬理学会 , 日本薬学会

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