Hiratani Ichiro

ヒラタニイチロウ | Hiratani Ichiro

Affiliation and department：

Research keywords (8)： 1細胞全ゲノム解析 , Hi-C , ゲノム三次元構造 , 発生・分化 , 全ゲノム解析 , 染色体 , エピジェネティクス , DNA複製

Research theme for competitive and other funds (9)：

2020 - 2026 1細胞全ゲノム解析の第二世代化と多次元化への挑戦
2020 - 2023 Exploration of the origin of intratumoral heterogeneity in squamous cell carcinoma by single-cell analysis
2018 - 2023 Dynamics of chromatin potential associating with cellular differentiation and its molecular mechanism
2019 - 2022 Stability and flexibility of the DNA replication program revealed by single-cell DNA replication sequencing in vivo
2018 - 2022 Mechanism for establishing connections between homologous chromosomes in mammalian meiosis

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Papers (41)：

Saori Takahashi, Hirohisa Kyogoku, Takuya Hayakawa, Hisashi Miura, Asami Oji, Yoshiko Kondo, Shin-Ichiro Takebayashi, Tomoya S Kitajima, Ichiro Hiratani. Embryonic genome instability upon DNA replication timing program emergence. Nature. 2024
Rory T. Cerbus, Ichiro Hiratani, Kyogo Kawaguchi. Homeotic and non-homeotic patterns in the tetrapod vertebral formula. 2024
Rawin Poonperm, Saya Ichihara, Hisashi Miura, Akie Tanigawa, Koji Nagao, Chikashi Obuse, Takashi Sado, Ichiro Hiratani. Replication dynamics identifies the folding principles of the inactive X chromosome. Nature Structural & Molecular Biology. 2023. 30. 8. 1224-1237
Kei Fukuda, Takeshi Shimi, Chikako Shimura, Takao Ono, Takehiro Suzuki, Kenta Onoue, Satoko Okayama, Hisashi Miura, Ichiro Hiratani, Kazuho Ikeda, et al. Epigenetic plasticity safeguards heterochromatin configuration in mammals. Nucleic Acids Research. 2023
Kosuke Yamaguchi, Xiaoying Chen, Asami Oji, Ichiro Hiratani, Pierre-Antoine Defossez. Large-Scale Chromatin Rearrangements in Cancer. Cancers. 2022. 14. 10

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MISC (3)：

Rawin Poonperm, Ichiro Hiratani. Formation of a multi-layered 3-dimensional structure of the heterochromatin compartment during early mammalian development. Development Growth and Differentiation. 2021. 63. 1. 5-17
高橋沙央里, 三浦尚, 柴田隆豊, 長尾恒治, 小布施力史, 竹林慎一郎, 平谷伊智朗. 1細胞全ゲノムDNA複製タイミング解析手法とマウス初期胚解析への応用に向けて. 日本細胞生物学会大会(Web). 2019. 71st
高橋沙央里, 三浦尚, 柴田隆豊, 長尾恒治, 小布施力史, 竹林慎一郎, 平谷伊智朗. マウスES細胞分化および初期胚発生過程における1細胞全ゲノムDNA複製タイミング解析. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd

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