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J-GLOBAL ID：202001017038890030 Update date: Mar. 19, 2025

Mizutani Shinsuke

ミズタニシンスケ | Mizutani Shinsuke

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Affiliation and department：
Job title： Assistant Professor

Research field (5)： Laboratory animal science , Genetics , Pathobiochemistry , Tumor biology , Hematology and oncology

Research keywords (6)： B細胞リンパ腫 , 多発生骨髄腫 , Apoptosis , p53 , RUNX1 , CRISPR/Cas9

Research theme for competitive and other funds (4)：

2023 - 2026 Identification of pathogenesis-promoting interferon-stimulated genes and development of regulatory strategies in mature B-cell tumors
2022 - 2025 Generation of RSK2/AKT/S6K tripple inhibitor for mature lymphoid malignancies
2021 - 2023 Elucidation of the high-grade pathogenesis of universal mature B cell tumor model by using comprehensive gene editing
2020 - 2022 Elucidation for novel target of aggressive B cell lymphoma by whole genome in vivo CRISPR/Cas9 screening

Papers (49)：

Yu Inoue, Taku Tsukamoto, Kentaro Mizuhara, Chika Maekura, Takahisa Nakamura, Haruya Okamoto, Takahiro Fujino, Shinsuke Mizutani, Yuji Shimura, Ayano Maruyama, et al. Primary Cutaneous CD8-positive Aggressive Epidermotropic Cytotoxic T-cell Lymphoma Complicated by Paraneoplastic Encephalitis. Internal medicine (Tokyo, Japan). 2025
Haruya Okamoto, Shinsuke Mizutani, Taku Tsukamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Kentaro Mizuhara, Ayako Muramatsu, Reiko Isa, Takahiro Fujino, Yuji Shimura, et al. Robust anti-myeloma effect of TAS0612, an RSK/AKT/S6K inhibitor, with venetoclax regardless of cytogenetic abnormalities. Leukemia. 2024
Yui Niiyama-Uchibori, Shinsuke Mizutani, Taku Tsukamoto, Haruya Okamoto, Daisuke Ide, Akio Onishi, Daishi Kato, Takahiro Fujino, Yuji Shimira, Aya Miyagawa-Hayashino, et al. Small cell pattern of ALK-negative anaplastic large cell lymphoma with double-hit rearrangements of DUSP22 and TP63. EJHaem. 2024. 5. 4. 798-801
Wakana Hashiro, Akihiro Miyashita, Yuka Kawaji-Kanayama, Haruya Okamoto, Takahiro Fujino, Taku Tsukamoto, Shinsuke Mizutani, Yuji Shimura, Junya Kuroda. Good's Syndrome With Pure Red Cell Aplasia and Subclinical Myasthenia Gravis: A Case Report and Review of Literature. Cureus. 2024. 16. 5. e59654
Chie Yamamoto, Masashi Taniguchi, Keitaro Furukawa, Toru Inaba, Yui Niiyama, Daisuke Ide, Shinsuke Mizutani, Junya Kuroda, Yoko Tanino, Keisuke Nishioka, et al. Nirmatrelvir Resistance in an Immunocompromised Patient with Persistent Coronavirus Disease 2019. Viruses. 2024. 16. 5. 718-718

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MISC (112)：

岡本明也, 水谷信介, 民西葉子[桂川], 水原健太郎, 村松彩子, 伊佐怜子, 藤野貴大, 塚本拓, 志村勇司, 谷脇雅文, et al. TAS0612の抗骨髄腫効果と染色体異常に関わらないvenetoclaxによる効果増強. 日本血液学会学術集会. 2024. 86回. O1-1
大西朗生, 宮川文, 岡本明也, 民西葉子, 藤野貴大, 塚本拓, 水谷信介, 志村勇司, 小西英一, 黒田純也. 悪性リンパ腫におけるPDPK1,RSK2,AKTの活性化状態と予後因子としての意義. 日本血液学会学術集会. 2024. 86回. P1-2
知念祥太郎, 小倉圭史, 井上祐, 新山侑生, 宮下明大, 中村隆久, 水原健太郎, 金山悠加, 藤野貴大, 塚本拓, et al. 京都府立医科大学における難治性大細胞型B細胞性リンパ腫に対するtisagenlecleucel療法の成績. 日本血液学会学術集会. 2024. 86回. O2-4
井上祐, 岡本明也, 宮下明大, 金山悠加, 知念祥太郎, 藤野貴大, 塚本拓, 志村勇司, 水谷信介, 兼子裕人, et al. 骨髄異形成症候群におけるアザシチジン1サイクル中の重度血小板減少と核型が予後に与える影響. 日本血液学会学術集会. 2024. 86回. O2-3
知念祥太郎, 小倉圭史, 井上祐, 新山侑生, 宮下明大, 中村隆久, 水原健太郎, 金山悠加, 藤野貴大, 塚本拓, et al. 京都府立医科大学における難治性大細胞型B細胞性リンパ腫に対するtisagenlecleucel療法の成績. 日本血液学会学術集会. 2024. 86回. O2-4

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Books (1)：

造血器腫瘍アトラス第5 版
日本医事新報社 2016

Education (2)：

2009 - 2013 京都府立医科大学大学院医学研究科統合医科学専攻(がんプロフェッショナル養成プラン)
2000 - 2006 京都府立医科大学医学部医学科

Professional career (1)：

PhD (medicine) (Kyoto Prefectural University of Medicine)

Work history (8)：

2022/04 - 現在京都府立医科大学内科学教室血液内科学部門学内講師
2021/04 - 2022/03 Kyoto Prefectural University of Medicine Division of Hematology and Oncology, Department of Medicine Assistant Professor
2020/04 - 2021/03 Kyoto Prefectural University of Medicine Division of Hematology and Oncology, Department of Medicine Clinical Assistant Professor
2016/08 - 2020/03 The Walter and Eliza Hall Institute of Medical Research Blood Cell and Blood Cancer Division Post doctoral fellow
2013/04 - 2016/07 Kyoto Prefectural University of Medicine Division of Hematology and Oncology, Department of Medicine Clinical Assistant Professor

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Committee career (1)：

2023/07 - 現在日本検査血液学会認定血液検査技師試験小委員会委員

Awards (4)：

2021/11 - ENT M Dr.浅野登&暉子基金医学基礎研究助成事業奨励金受賞
2021/06 - 日本骨髄腫学会 2021年度日本骨髄腫学会奨励賞
2021/06 - 日本骨髄腫学会 2021年第45回日本骨髄腫学会学術集会優秀演題賞
2015/12 - 公益財団法人上原生命科学財団平成27年度海外留学助成金リサーチフェローシップ

Association Membership(s) (12)：

日本感染症学会 , 日本遺伝性腫瘍学会 , 日本検査血液学会 , 日本骨髄腫学会 , 日本造血・免疫細胞療法学会 , The Japanese Society on Thrombosis and Hemostasis , The Japan Society of Human Genetics , The Japan Society of Transfusion Medicine and Cell Therapy , Japanese Society of Laboratory Medicine , 日本臨床腫瘍学会 , 日本血液学会 , 日本内科学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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