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Rchr

J-GLOBAL ID：202001017677559035 Update date: Feb. 13, 2025

Gotoh Akihiko

Research field (1)： Hematology and oncology

Research theme for competitive and other funds (7)：

2024 - 2027 STAMP阻害薬を使用する慢性骨髄性白血病患者における骨髄系遺伝子変異の解析
2023 - 2026 骨髄増殖性腫瘍幹細胞におけるCD44を中心とする接着因子発現・機能の調節機構解明
2021 - 2024 ALK陽性ALCLにおけるTP53欠失が与える臨床的影響の解明と層別化治療の構築
2018 - 2022 Novel ER stress-mediated therapy for tumor clones in myelofibrosis
2015 - 2019 Selective elimination of tumor clones of primary myelofibrosis based on drug repositioning

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Papers (171)：

Seiichi Okabe, Yuya Arai, Akihiko Gotoh. Correspondence to: "Combination therapies with ponatinib and asciminib in a preclinical model of chronic myeloid leukemia blast crisis with compound mutations", Curik N et al. Leukemia. 2024; 38: 1415-1418. Leukemia. 2025
Shunsuke Otsuki, Seiichiro Katagiri, Yuya Arai, Shohei Wakamatsu, Mituru Moriyama, Akiko Yamada, Tamiko Suguro, Michiyo Asano, Seiichiro Yoshizawa, Daigo Akahane, et al. [Comparison of IPSS-R and IPSS-M in newly diagnosed myelodysplastic neoplasms: a single-center study]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2025. 66. 1. 7-11
Seiichi Okabe, Yuya Arai, Akihiko Gotoh. Targeting the insulin-like growth factor-1 receptor to overcome imatinib resistance in chronic myeloid leukemia. Discover oncology. 2024. 15. 1. 835-835
Seiichi Okabe, Yuya Arai, Akihiko Gotoh. Vitamin K2 Protects Against SARS-CoV-2 Envelope Protein-Induced Cytotoxicity in Chronic Myeloid Leukemia Cells and Enhances Imatinib Activity. International journal of molecular sciences. 2024. 25. 21
Keita Kirito, Yuka Sugimoto, Akihiko Gotoh, Katsuto Takenaka, Michiko Ichii, Tadaaki Inano, Shuichi Shirane, Masafumi Ito, Oleh Zagrijtschuk, Albert Qin, et al. Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera. International journal of hematology. 2024

MISC (275)：

橋本由徳, 枝廣陽子, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, 臼杵憲祐, et al. A nationwide survey on Japanese patients with essential thrombocythemia: JSH-MPN-R18 study(和訳中). 日本血液学会学術集会. 2021. 83回. OS3-3
落合友則, 橋本由徳, 枝廣陽子, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, et al. Secondary malignancies in Japanese patients with myeloproliferative neoplasms: JSH-MPN-R18 study(和訳中). 日本血液学会学術集会. 2021. 83回. OS3-4
臼杵憲祐, 池添隆之, 石山謙, 神田善伸, 後藤明彦, 松田貴久, 下野明彦, 秋山仁泉, 小原直, 西村純一. 発作性夜間ヘモグロビン尿症患者(PNH)に対するラブリズマブ特定使用成績調査の中間解析. 日本血液学会学術集会抄録(Web). 2021. 83rd. PS-1
赤羽大悟, 長谷川大輔, 大月俊輔, 山田ありさ, 片桐誠一朗, 吉澤成一郎, 藤本博昭, 古屋奈穂子, 稲垣夏子, 後藤明彦. 成人で診断されたWHIM症候群. 臨床血液. 2021. 62. 6
森山充, 赤羽大悟, 森谷昇太, 山田ありさ, 今井美沙, 今井美沙, 荒木真理人, 小松則夫, 宮澤啓介, 後藤明彦, et al. ERストレスはruxolitinibの変異CALR導入細胞増殖抑制効果を増強する. 日本血液学会学術集会抄録(Web). 2020. 82nd

Professional career (2)：

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