Rchr
J-GLOBAL ID：202001020013565403
Update date: Nov. 26, 2023
YANG YINJIE
YANG YINJIE
Research field (1)：
Hematology and oncology
Research keywords (1)：
MPN, CALR
Research theme for competitive and other funds (2)：
- 2018 - 2021 Development of novel therapeutic strategies for myeloproliferative neoplasms caused by mutant CALR
- 2016 - 2016 変異CALR遺伝子による骨髄増殖性腫瘍の発症メカニズムの解明
Papers (14)：
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Federico De Marchi, Maho Okuda, Soji Morishita, Misa Imai, Terumi Baba, Mei Horino, Yosuke Mori, Chiho Furuya, Satoko Ogata, Yinjie Yang, et al. Clinical and biological relevance of CREB3L1 in Philadelphia chromosome-negative myeloproliferative neoplasms. Leukemia research. 2022. 119. 106883-106883
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Tadaaki Inano, Marito Araki, Soji Morishita, Misa Imai, Yoshihiko Kihara, Maho Okuda, Yinjie Yang, Masafumi Ito, Satoshi Osaga, Hiroyuki Mano, et al. Author Correction: Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia. Scientific reports. 2022. 12. 1. 1115-1115
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Tadaaki Inano, Marito Araki, Soji Morishita, Misa Imai, Yoshihiko Kihara, Maho Okuda, Yinjie Yang, Masafumi Ito, Satoshi Osaga, Hiroyuki Mano, et al. Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia. Scientific reports. 2021. 11. 1. 17702-17702
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Nami Masubuchi, Marito Araki, Yinjie Yang, Erina Hayashi, Misa Imai, Yoko Edahiro, Yumi Hironaka, Yoshihisa Mizukami, Yoshihiko Kihara, Hiraku Takei, et al. Mutant calreticulin interacts with MPL in the secretion pathway for activation on the cell surface. Leukemia. 2020. 34. 2. 499-509
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Marito Araki, Yinjie Yang, Misa Imai, Yoshihisa Mizukami, Yoshihiko Kihara, Yoshitaka Sunami, Nami Masubuchi, Yoko Edahiro, Yumi Hironaka, Satoshi Osaga, et al. Homomultimerization of mutant calreticulin is a prerequisite for MPL binding and activation. Leukemia. 2019. 33. 1. 122-131
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MISC (19)：
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Kihara Yoshihiko, Araki Marito, Yang Yinjie, Imai Misa, Masubuchi Nami, Mizukami Yoshihisa, Morishita Soji, Ohsaka Akimichi, Komatsu Norio. 癌原性を有する変異CALRの蓄積を支配するメカニズム(Mechanisms Governing the Accumulation of Mutant CALR Harboring Oncogenic Property). 順天堂醫事雑誌. 2019. 65. 6. 567-567
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Masubuchi Nami, Araki Marito, Hayashi Erina, Yang Yinjie, Imai Misa, Kihara Yoshihiko, Mizukami Yoshihisa, Hironaka Yumi, Takei Hiraku, Edahiro Yoko, et al. 変異分子シャペロンおよびサイトカイン受容体の関与が細胞形質転換に必要である(Engagement of Mutant Molecular Chaperone and Cytokine Receptor in the Secretary is Required for the Cellular Transformation). 順天堂醫事雑誌. 2019. 65. 6. 572-573
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Mizukami Yoshihisa, Araki Marito, Hayashi Erina, Yang Yinjie, Hironaka Yumi, Kihara Yoshihiko, Masubuchi Nami, Imai Misa, Ohsaka Akimichi, Komatsu Norio. CALRのKDEL配列の喪失およびC末端の陰性荷電から陽性荷電アミノ酸への変化だけでは癌原性は生じない(Loss of KDEL and Conversion from Negatively to Positively Charged Amino Acids at the C-terminus of CALR Was Not Sufficient for the Oncogenicity). 順天堂醫事雑誌. 2019. 65. 6. 580-581
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Edahiro Yoko, Araki Marito, Yang Yinjie, Masubuchi Nami, Mizukami Yoshihisa, Imai Misa, Kihara Yoshihiko, Ohsaka Akimichi, Komatsu Norio. 変異calreticulinによるMPN発症の分子メカニズム(The Molecular Mechanism of MPN Development by Mutant Calreticulin). 順天堂醫事雑誌. 2019. 65. 6. 585-585
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Kihara Yoshihiko, Araki Marito, Yang Yinjie, Imai Misa, Masubuchi Nami, Mizukami Yoshihisa, Hironaka Yumi, Morishita Soji, Ohsaka Akimichi, Komatsu Norio. 変異calreticulinの蓄積を支配するメカニズム(Mechanisms Governing the Accumulation of Mutant Calreticulin). 順天堂醫事雑誌. 2018. 64. 6. 479-480
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Education (1)：
- Tokyo University of Pharmacy and Life Sciences Graduate School of Life Science
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