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J-GLOBAL ID:202001020905738027   Update date: Jan. 03, 2025

Sasaki Keisuke

ササキ ケイスケ | Sasaki Keisuke
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Affiliation and department:
Research field  (3): Animal production science ,  Zoological sciences ,  Laboratory animal science
Research keywords  (6): in vitro oogenesis ,  ゲノム育種 ,  Epigenetics ,  Genome editing ,  Genomic imprinting ,  Oocyte
Research theme for competitive and other funds  (6):
  • 2024 - 2027 母性エピゲノムの異常を克服したマウス体外卵作出系の構築と非齧歯類への応用
  • 2024 - 2026 エピゲノムからみた試験管内卵の品質のゆらぎの理解と高品質・高均質化に向けた試み
  • 2023 - 2024 高品質な卵の産生を実現するマウス高度体外卵作出系の開発
  • 2021 - 2024 卵子型エピゲノム形成におけるH3K36メチル化酵素ファミリーの機能解明
  • 2018 - 2021 In vitro卵作出系を応用した新規手法によるインプリント機構の解明
Show all
Papers (14):
  • Yuhkoh Satouh, Emiko Suzuki, Keisuke Sasaki, Ken Sato. Improved low-invasive mRNA electroporation method into immature mouse oocytes visualizes protein dynamics during development. Biology of Reproduction. 2024. 111. 4. 931-941
  • Yuhkoh Satouh, Emiko Suzuki, Keisuke Sasaki, Ken Sato. Improved mRNA electroporation into immature oocytes to examine protein dynamics during development. bioRxiv. 2023
  • Daisuke Suzuki, Keisuke Sasaki, Soichiro Kumamoto, Keisuke Tanaka, Hidehiko Ogawa. Dynamic Changes of Gene Expression in Mouse Mural Trophectoderm Regulated by Cdx2 During Implantation. Frontiers in Cell and Developmental Biology. 2022. 10. 945241
  • Keisuke Sasaki, Saaya Takaoka, Yayoi Obata. Oocyte-specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice. Journal of Reproduction and Development. 2021. 67. 3. 229-234
  • Keisuke Sasaki, Satoshi Hara, Reina Yamakami, Yusuke Sato, Saki Hasegawa, Tomohiro Kono, Kanako Morohaku, Yayoi Obata. Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice. Molecular Reproduction and Development. 2019. 86. 6. 614-623
more...
MISC (19):
  • Yuhkoh Satouh, Emiko Suzuki, Keisuke Sasaki, Ken Sato. Development of a low-invasive mRNA electroporation method into immature mouse oocytes and visualization of oocyte chromosomes during early embryogenesis. 57th Annual meeting of Society for the Study of Reproduction. 2024. 57. P-106
  • 佐々木恵亮, 柿沼俊枝, 佐々木麻智子, 大上厚志. 体外卵成長培養がマウス卵のエピジェネティクスに与える影響. 第116回日本繁殖生物学会講演要旨集. 2023. 116. OR3-24
  • 鈴木大介, 佐々木恵亮, 小川英彦. 転写因子Cdx2の下方制御はマウス壁栄養外胚葉の分化及び胚盤胞のoutgrowthに必要である. 第63回日本卵子学会学術集会プログラム. 2022. 63. H-8
  • 佐々木恵亮, 尾畑やよい. 卵母細胞特異的遺伝子ノックダウンシステムの開発. 第42回日本分子生物学会年会講演要旨集. 2019. フォーラム3F-09「有性生殖における染色体・クロマチン・核動態」. 90
  • 佐々木恵亮, 高岡沙綾, 尾畑やよい. 卵母細胞特異的ノックダウンシステムの確立. 第112回日本繁殖生物学会講演要旨集. 2019. 112. OR1-23
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Lectures and oral presentations  (19):
  • Development of a low-invasive mRNA electroporation method into immature mouse oocytes and visualization of oocyte chromosomes during early embryogenesis.
    (57th Annual meeting of Society for the Study of Reproduction 2024)
  • 体外卵成長培養がマウス卵のエピジェネティクスに与える影響
    (第116回日本繁殖生物学会大会 2023)
  • 転写因子Cdx2の下方制御はマウス壁栄養外胚葉の分化及び胚盤胞のoutgrowthに必要である
    (第63回日本卵子学会学術集会 2022)
  • 卵母細胞特異的遺伝子ノックダウンシステムの開発
    (第42回日本分子生物学会年会 2019)
  • 卵母細胞特異的ノックダウンシステムの確立
    (第112回日本繁殖生物学会大会 2019)
more...
Education (3):
  • 2011 - 2014 Hokkaido University Graduate School of Agriculture
  • 2009 - 2011 Hokkaido University Graduate School of Agriculture
  • 2005 - 2009 Hokkaido University Faculty of Agriculture
Professional career (1):
  • 博士(農学) (北海道大学)
Work history (4):
  • 2021/02 - 現在 Gunma University Bioresource Center, Graduate School of Medicine Assistant Professor
  • 2018/04 - 2021/01 Japan Society for the Promotion of Science Research Fellow (PD)
  • 2018/04 - 2021/01 Tokyo University of Agriculture
  • 2014/04 - 2018/03 Tokyo University of Agriculture
Awards (3):
  • 2022/09 - The Society for Reproduction and Development JRD Outstanding Paper Award 2021 Oocyte-specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice
  • 2020/04 - Molecular Reproduction and Development TOP DOWNLOADED PAPER 2018-2019 Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice
  • 2017/04 - National Academy of Sciences PNAS Cozzarelli Prize 2016 - Class II (Biological Science) Complete in vitro generation of fertile oocytes from mouse primordial germ cells
Association Membership(s) (3):
日本ゲノム編集学会 ,  日本繁殖生物学会 ,  日本畜産学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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