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J-GLOBAL ID：202001020941356076 Update date: Feb. 05, 2025

Iijima Junko

イイジマジュンコ | Iijima Junko

Affiliation and department：
Research theme for competitive and other funds (5)：

2022 - 2024 Analysis of the mechanism of tau pathology focusing on O-glycan using Alzheimer's disease model mice.
2018 - 2019 脳型トランスフェリンを介した新規フェロトーシスが神経細胞死に及ぼす影響
2014 - 2018 Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling.
2012 - 2015 ヒアルロン酸合成過程で発見された新奇オリゴ糖、その機能と個体老化における意義
2007 - 2007 β-Klothoノックアウトマウスを用いたコレステロール代謝の解析

Papers (10)：

Yuriko Tachida, Junko Iijima, Kazuto Takahashi, Hideaki Suzuki, Yasuhiko Kizuka, Yoshiki Yamaguchi, Katsunori Tanaka, Miyako Nakano, Daisuke Takakura, Nana Kawasaki, et al. O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production. The Journal of biological chemistry. 2023. 299. 7. 104905-104905
Junko Iijima, Kyoka Hoshi, Hiromi Ito, Mayumi Kanno, Yuta Murakami, Koichi Takahashi, Kana Matsumoto, Yoshiki Yamaguchi, Madoka Nakajima, Masakazu Miyajima, et al. Total transferrin in cerebrospinal fluid is a novel biomarker for spontaneous intracranial hypotension. FUKUSHIMA JOURNAL OF MEDICAL SCIENCE. 2021. 67. 2. 64-70
Iijima J, Kobayashi S, Kitazume S, Kizuka Y, Fujinawa R, Korekane H, Shibata T, Saitoh SI, Akashi-Takamura S, Miyake K, et al. Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling. Glycobiology. 2017. 27. 11. 1006-1015
Kikuchi K, Narita T, Pham VT, Iijima J, Hirota K, Keka IS, Mohiuddin, Okawa K, Hori T, Fukagawa T, et al. Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination. Cancer Res. 2013. 73. 14. 4362-71
Sakabe I, Asai A, Iijima J, Maruyama M. Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells. Immun Ageing. 2012. 9. 2

MISC (7)：

飯島順子, 立田由里子, 高橋一人, 鈴木英明, 武藤優衣, 三浦里織, 新堂晃大, 松葉由紀夫, 斉藤貴志, 川口寧, et al. 脳血管内皮型APP770に着目したCAAモデルマウスの開発. Dementia Japan. 2024. 38. 4. 634
飯島順子, 芳賀淑美, 千葉靖典, 植田幸嗣, 西道隆臣, 佐原成彦, 北爪しのぶ. ADモデルマウスを用いたタウのO型糖鎖修飾の解析. 老年精神医学雑誌. 2022. 33. 増刊II. 240-240
飯島順子, 芳賀淑美, 千葉靖典, 植田幸嗣, 西道隆臣, 佐原成彦, 北爪しのぶ. ADモデルマウスを用いたタウのO型糖鎖修飾の解析. Dementia Japan. 2022. 36. 4. 750-750
飯島順子, 中山洋佑, 坂部勇, 宮崎忠昭, 丸山光生. 新規GEF, Zizimin2/DOCK11の機能と免疫老化における役割の解析. 基礎老化研究. 2011. 35. 2. 38
坂部勇, 嶋田貴志, 飯島順子, 本田三男, 直江吉則, 丸山光生. 老化関連因子Zizimin2/Dock11の獲得免疫系における機能解析. 基礎老化研究. 2011. 35. 2. 38

Books (1)：

Lectures and oral presentations (27)：

血管性アミロイドの基礎
(第43回日本認知症学会学術集会 2024)
脳血管内皮型APP770に着目したCAAモデルマウスの開発
(第43 回日本認知症学会学術集会 2024)
Transport and functional analysis of amyloid-β precursor protein 770 from vascular endothelial cells to platelets.
O-糖鎖付加修飾が APP の細胞内輸送と Aβ の産生量を規定する.
(第 42 回日本認知症学会学術集会)
O-GalNAc 糖鎖付加は Aβ 前駆体タンパク質(APP )の細胞内輸送と Aβ 産生を規定する
(第 42 回日本糖質学会年会 2023)

Professional career (1)：

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