Research field (5)：
Neuroscience - general
, Basic brain sciences
, Cognitive neuroscience
, Nervous system function
, Animals: biochemistry, physiology, behavioral science
Research theme for competitive and other funds (7)：
2022 - 2025 皮質と皮質下のタンパクリン酸化からみる麻酔・鎮静・睡眠の異同
2022 - 2025 Cortico-preoptic circuit regulating sleep and sedation
2020 - 2025 SIK3および新規睡眠制御分子による睡眠制御シグナルカスケードの解明
2022 - 2025 霊長類の前頭極のメタ認知機能に起因する強迫性障害の機序の解明
2022 - 2024 Functional role of the macaque frontopolar cortex for 'thought experiment' during sleep and awake resting state
2021 - 2023 Neuronal circuit for sedative/hypnotic actions of alpha-2 adrenergic agonist
2008 - 2009 大脳前頭連合野における仮想上の動作プランが認知と運動の統合過程に果たす役割
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Papers (18)：
Paul Brodersen, Hannah Alfonsa, Lukas Krone, Cristina Blanco-Duque, Angus Fisk, Sarah J. Flaherty, Mathilde Guillaumin, Yi-Ge Huang, Martin C. Kahn, Laura E. McKillop, et al. Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions. PLOS Computational Biology. 2024
Mathilde C. C. Guillaumin, Christian D. Harding, Lukas B. Krone, Tomoko Yamagata, Martin C. Kahn, Cristina Blanco-Duque, Gareth T. Banks, Patrick M. Nolan, Stuart N. Peirson, Vladyslav V. Vyazovskiy. Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice. bioRxiv. 2023
Hannah Alfonsa, Richard J. Burman, Paul J. N. Brodersen, Sarah E. Newey, Kashif Mahfooz, Tomoko Yamagata, Marios C. Panayi, David M. Bannerman, Vladyslav V. Vyazovskiy, Colin J. Akerman. Intracellular chloride regulation mediates local sleep pressure in the cortex. Nature Neuroscience. 2022. 26. 1. 64-78
Tomoko Yamagata, Martin C. Kahn, José Prius-Mengual, Elise Meijer, Merima Šabanović, Mathilde C. C. Guillaumin, Vincent van der Vinne, Yi-Ge Huang, Laura E. McKillop, Aarti Jagannath, et al. The hypothalamic link between arousal and sleep homeostasis in mice. Proceedings of the National Academy of Sciences. 2021. 118. 51
Lukas B. Krone, Tomoko Yamagata, Cristina Blanco-Duque, Mathilde C. C. Guillaumin, Martin C. Kahn, Vincent van der Vinne, Laura E. McKillop, Shu K. E. Tam, Stuart N. Peirson, Colin J. Akerman, et al. A role for the cortex in sleep-wake regulation. Nature Neuroscience. 2021. 24. 9. 1210-1215
中山 義久, 山形 朋子, 有村 奈利子, 丹治 順, 星 英司. 運動実行に関わる神経細胞活動の前頭葉6領域間の比較(Comparison of movement-related neuronal activity recorded from six different areas in the frontal cortex of macaques). 神経化学. 2010. 49. 2-3. 637-637
有村 奈利子, 中山 義久, 山形 朋子, 佐賀 洋介, 丹治 順, 星 英司. 行動の抽象表現に基づく運動計画における大脳基底核と前頭前野の関与(Involvement of the basal ganglia and the frontal cortex in action planning as mediated by the abstract representation of action). 神経化学. 2010. 49. 2-3. 637-637
Processing of visual signals for direct specification of motor targets and for conceptual representation of action targets in the dorsal and ventral premotor cortex. Tamagawa Brain Science Institute bulletin. 2010. 3. 25-39
Lectures and oral presentations (4)：
Cortico-subcortical dynamics during sleep-induced and sedation-induced loss/recovery of consciousness
(EROTO UK-Japan Joint Symposium on Circadian rhythms and Sleep 2024)
Effects of chemogenetic stimulation of melanopsin cells in the retina on light induced sleep in mice
(eSLEEP EUROPE 2023 2023)
Rapid state reversibility from deep dexmedetomidine sedation induced by photoactivation of lateral preoptic GAD2 neurons in mice
(NEUROSCIENCE 2021, 50th Annual Meeting of SfN 2021)
Rapid state reversibility from deep dexmedetomidine sedation induced by photoactivation of lateral preoptic GAD2 neurons in mice
(NEUROSCIENCE 2021, 50th Annual Meeting of SfN 2021)
Education (5)：
2007 - 2010 Tamagawa University Graduate School, Division of Engineering Brain Informatics Major
2007 - 2010 Tamagawa University Graduate School of Engineering Brain Informatics Major
2005 - 2007 University of Tsukuba Graduate School, Division of Environmental Science Master's Program in Biological Sciences
2005 - 2007 University of Tsukuba Graduate School of Life and Environmental Sciences Master’s Program in Biological Sciences
2001 - 2005 University of Tsukuba Second Cluster of Colleges College of Biological Sciences
Professional career (1)：
PhD (Engineering) (Tamagawa University)
Work history (15)：
2022/04 - 現在 Toho University Faculty of Medicine School of Medicine Assistant Professor
2021/11 - 現在 RIKEN Center for Brain Science (CBS) Imagination and Executive Functions Researher Postdoc
2021/05 - 2022/03 Toho University Faculty of Medicine School of Medicine Assistant Professor
2017/09 - 2021/04 University of Oxford Nuffield Department of Clinical Neurosciences, Medical Devision Researher Postdoc
2017/09 - 2021/04 University of Oxford Nuffield Department of Clinical Neurosciences Postdoctoral Research Scientist in Sleep Neurobiology
2016/08 - 2017/08 University of Oxford Department of Physiology, Anatomy & Genetics Researher Postdoc
2016/08 - 2017/08 University of Oxford Department of Physiology, Anatomy & Genetics Postdoctoral Research Scientist in Sleep/Neurobiology
2015/04 - 2016/07 University of Oxford Department of Physiology, Anatomy & Genetics Researher Postdoc
2015/04 - 2016/07 University of Oxford Department of Physiology, Anatomy & Genetics Visiting Researcher
