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J-GLOBAL ID：202101002039634410
Update date: Apr. 18, 2025 Kubo Shintaroh
クボ シンタロウ | Kubo Shintaroh
RIKEN Cluster for Pioneering Research
About RIKEN Cluster for Pioneering Research
Job title： Special Postdoctoral Researcher
Other affiliations (1)：
- The University of Tokyo The Graduate School of Engineering Department of Applied Chemistry
Research keywords (4)：
molecular motor
, molecular dynamics simulation
, microtubule
, electron microscopy
Research theme for competitive and other funds (4)： - 2022 - 2027 微小管の翻訳後修飾による軸糸内輸送網の制御方法に関する分子シミュレーション研究
- 2021 - 2024 分子モーターの適応進化機構の理論的解明とそれを応用した高機能化デザイン
- 2020 - 2021 Elucidation of structural change of axoneme doublet microtubule using cryo electron microscopy and molecular dynamics simulation
- 2019 - 2019 Understanding tubulin conformational change in doublet microtubule by cryo-EM and molecular dynamics simulation
- Shintaroh Kubo, Yasushi Okada. The ATPase asymmetry: Novel computational insight into coupling diverse FO motors with tripartite F1. Biophysical Journal. 2025. 124. 6. 891-900
- Haoqiang K. He, Shintaroh Kubo, Qianru H. Lv, Azusa Kage, Muneyoshi Ichikawa. Dynein-2 is tuned for the A-tubule of the ciliary doublet through tubulin tyrosination. 2025
- Shintaroh Kubo, Yasushi Okada, Shoji Takada. Theoretical insights into rotary mechanism of MotAB in the bacterial flagellar motor. Biophysical Journal. 2024. 123. 20. 3587-3599
- Shun Kai Yang, Shintaroh Kubo, Corbin Black, Katya Peri, Daniel Dai, Thibault Legal, Melissa Valente, Jacek Gaertig, Khanh Huy Bui. Effect of alpha-tubulin acetylation on the doublet microtubule structure. eLife. 2024. 12. RP92219
- Yukihiro Shiga, Kazuki Hashimoto, Kosuke Fujita, Shigeto Maekawa, Kota Sato, Shintaroh Kubo, Kazuhide Kawase, Kana Tokumo, Yoshiaki Kiuchi, Sotaro Mori, et al. Identification of OPTN p.(Asn51Thr): A novel pathogenic variant in primary open-angle glaucoma. Genetics in Medicine Open. 2023. 2. 100839-100839
- 三留 規誉, 久保 進太郎, 太田 澄恵, 高嶋 ひかる, 重藤 優斗, 新稲 亮, 高田 彰二. ヘテロ変異導入と分子シミュレーションによるFoF1-ATP合成酵素の回転機構の解析. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [1T18m-04]
-
Functional Analysis of F-ATPase Motion Using Multiscale Simulations
(Biophysical Society Annual Meetings 2025 2025) -
バクテリア鞭毛モーター: MotAB の回転機構に関する理論研究
(日本生体エネルギー研究会 第50回討論会 2024) -
Cryo-EM and Theoretical Studies Highlight the Critical Role of Outer Junctions in Native Double Microtubules
(Emerging Theoretical Approaches to Complement Single-Particle Cryo-Electron Microscopy 2024) -
FoF1-ATPaseのATP合成過程に関する理論的研究
(第13回分子モーター討論会 2024) -
Exploring the Impact of Microtubule Surface Architecture on Dynein Dynamics
(Gordon Research Conference 2024 2024)
- 2017 - 2020 Kyoto University Graduate School of Science Division of Biological Sciences
- 2015 - 2017 Kyoto University Graduate School of Science Division of Biological Sciences
- 2011 - 2015 Sophia University Faculty of Science and Technology Department of Materials and Life Sciences
- PhD(Science) (Kyoto University)
- 2025/04 - 現在 RIKEN Cluster for Pioneering Research Special Postdoctoral Researcher
- 2024/04 - 現在 The University of Tokyo The Graduate School of Engineering Department of Applied Chemistry Postdoctoral researcher
- 2021/04 - 2024/03 The University of Tokyo Graduate School of Medicine
- 2021/04 - 2022/03 McGill University Department of Anatomy and Cell Biology, Faculty of Medicine and Health Science
- 2020/04 - 2021/03 McGill University
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- 2024/12 - 50th Japan BioEnergetics Group 若手発表賞 バクテリア鞭毛モーター: MotAB の回転機構に関する理論研究
- 2024/06 - IUPAB2024 'Student and Early Career Researcher' Poster Award Coarse-Grained Molecular Dynamics Simulations of Rotational Asymmetry in FOF1 ATPase
- 2019/09 - 第57回日本生物物理学会 学生発表賞 細胞質ダイニンの微小管結合ドメインに依存する運動方向性に関する研究
- 2019/05 - 京都大学 理学研究科基金奨学金
- 2017/09 - 日本分子科学会 優秀ポスター賞 細胞質ダイニンの一方向輸送性能に関する分子シミュレーション研究
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