Rchr
J-GLOBAL ID：202101002968440744
Update date: Jan. 30, 2024
Miura Hiromi
ミウラ ヒロミ | Miura Hiromi
Affiliation and department：
Job title：
Assistant Professor
Research field (2)：
Genomics
, Laboratory animal science
Research keywords (3)：
Genetic Engineering
, Genetically modified mouse
, Genome Editing
Research theme for competitive and other funds (6)：
- 2023 - 2027 Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy
- 2021 - 2025 Establishment of gene expression system by intron modification and its application for the functional analysis of diabetes-related genes
- 2020 - 2023 in vivoゲノム編集効率の最適化と疾患モデル動物遺伝子治療への応用
- 2016 - 2018 Easi-CRISPR for creating genetically modified mice using long ssDNA.
- 2015 - 2018 Development of novel method for generation of genome editing mice without ex vivo handling of embryos
- 2012 - 2015 Developmentandapplicationofmouseandcellmodelsforanalyses of HLA-dependent adverse drug reactions
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Papers (42)：
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Masato Ohtsuka, Jurai Imafuku, Shuho Hori, Aki Kurosaki, Ayaka Nakamura, Tsubasa Nakahara, Takashi Yahata, Kolari Bhat, Steven T Papastefan, So Nakagawa, et al. Delivering mRNAs to mouse tissues using the SEND system. bioRxiv : the preprint server for biology. 2023
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Masahiro Sato, Ayaka Nakamura, Marie Sekiguchi, Takashi Matsuwaki, Hiromi Miura, Channabasavaiah B Gurumurthy, Shigeru Kakuta, Masato Ohtsuka. Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes. Methods in molecular biology (Clifton, N.J.). 2023. 2631. 325-340
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Masayuki Tanaka, Keiko Yokoyama, Hideki Hayashi, Sanae Isaki, Kanae Kitatani, Ting Wang, Hisako Kawata, Hideyuki Matsuzawa, Channabasavaiah B Gurumurthy, Hiromi Miura, et al. CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice. Genome biology. 2022. 23. 1. 228-228
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Yusuke Niwa, Kenya Kamimura, Kohei Ogawa, Chiyumi Oda, Yuto Tanaka, Ryoko Horigome, Masato Ohtsuka, Hiromi Miura, Koichi Fujisawa, Naoki Yamamoto, et al. Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM-CHK2 Pathway. Journal of clinical medicine. 2022. 11. 3
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Hiromi Miura, Jurai Imafuku, Aki Kurosaki, Masahiro Sato, Yongjie Ma, Guisheng Zhang, Akiko Mizutani, Kenya Kamimura, Channabasavaiah B Gurumurthy, Dexi Liu, et al. Novel reporter mouse models useful for evaluating in vivo gene editing and for optimization of methods of delivering genome editing tools. Molecular therapy. Nucleic acids. 2021. 24. 325-336
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MISC (16)：
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三浦浩美, 三浦浩美, 稲垣豊, 佐藤正宏, 大塚正人. In vivoゲノム編集効率評価系モデルマウスの開発. 日本生化学会大会(Web). 2017. 90th. ROMBUNNO.3P-1386 (WEB ONLY)-1386]
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上村 顕也, 横尾 健, 阿部 寛幸, 小林 雄司, 大塚 正人, 三浦 浩美, 小川 光平, 品川 陽子, 井上 良介, 山際 訓, et al. 臓器特異的ハイドロダイナミック遺伝子導入法による肝疾患の遺伝子治療. 日本消化器病学会雑誌. 2016. 113. 臨増総会. A301-A301
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小林雄司, 上村顕也, 阿部寛幸, 大塚正人, 横尾健, 三浦浩美, 兼藤努, 須田剛士, 青柳豊, DEXI L, et al. 肝臓特異的ハイドロダイナミック法を用いたMatrix metalloproteinase13による肝線維化の遺伝子治療. 肝臓. 2015. 56. Supplement 2. A776-A776
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三浦浩美, 佐藤正宏, GURUMURTHY Channabasavaiah, 大塚正人. CRISPR/Cas9系を用いた新規ノックダウンマウス作製法の開発. J Reprod Dev. 2015. 61. Suppl. j119-j119
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大塚正人, GURUMURTHY Channabasavaiah, 三浦浩美, 佐藤正宏, 和田健太, 高橋剛. GONAD:採卵,顕微注入,移植を要しない新規ゲノム編集マウス作製法. J Reprod Dev. 2015. 61. Suppl. j152-j152
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