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J-GLOBAL ID：202101011528077337
Update date: Feb. 20, 2025 Sakane Sadatsugu
サカネ サダツグ | Sakane Sadatsugu
University of California, San Diego Department of Medicine
About University of California, San Diego Department of Medicine
Job title： Post-doc scholar
Other affiliations (1)：
- Osaka University Graduate School of Medicine Gastroenterology and Hepatology
- 2022 - 2025 The mechanism of alcohol-associated hepatitis with obesity via adipose tissue-liver crosstalk
- 2020 - 2022 The role of omega-6 fatty acid metabolism in non-alcoholic steatohepatitis
- 2018 - 2020 Targeting autophagy to improve alcoholic liver disease
- 2014 - 2018 The impact of hepatocyte apoptosis and autophagy in the process of livercarcinogenesis
- Li Gu, Yahui Zhu, Shuvro P Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng, Masafumi Ohira, Yuxiao Liu, Sadatsugu Sakane, Rodrigo Carlessi, et al. Author Correction: FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature. 2025. 638. 8051. E30
- Sadatsugu Sakane, Hayato Hikita. Revisiting the relationship between thyroid function and metabolic dysfunction-associated steatotic liver disease in the era of resmetirom. Journal of gastroenterology. 2025
- Li Gu, Yahui Zhu, Shuvro P. Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng, Masafumi Ohira, Yuxiao Liu, Sadatsugu Sakane, Rodrigo Carlessi, et al. FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Nature. 2025. 637. 8045. 461-469
- Hyun Young Kim, Sara Brin Rosenthal, Xiao Liu, Charlene Miciano, Xiaomeng Hou, Michael Miller, Justin Buchanan, Olivier B Poirion, Daisy Chilin-Fuentes, Cuijuan Han, et al. Multi-Modal Analysis of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease. Journal of hepatology. 2024
- Min Cong, Raquel Carvalho Gontijo Weber, Sadatsugu Sakane, Vivian Zhang, Chunyan Jiang, Kojiro Taura, Yuzo Kodama, Samuele DeMinicis, Souradipta Ganguly, David Brafman, et al. Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs. Hepatology Communications. 2024. 8. 11
- Kumiko Shirai, Hayato Hikita, Sadatsugu Sakane, Kazuhiro Murai, Akira Nishio, Kunimaro Furuta, Takahiro Kodama, Tomohide Tatsumi, Tetsuo Takehara. BINGE ALCOHOL INTAKE IN OBESITY INCREASES SERUM AND HEPATIC ETHYL ARACHIDONATE AND EXACERBATES LIVER INJURY. HEPATOLOGY. 2023. 78. S1585-S1585
- Kenji Fukumoto, Hayato Hikita, Sadatsugu Sakane, Kazuhiro Murai, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara. LYSOSOMAL DYSFUNCTION IN LIVER MACROPHAGES CONTRIBUTES TO NASH PATHOGENESIS. HEPATOLOGY. 2022. 76. S626-S627
- Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, Ryohei Narumi, Jun Adachi, Ryotaro Sakamori, Naruyasu Kakita, Yukinori Yamada, Tatsuya Sakamoto, Machiko Kai, et al. SERUM Fibulin3 IS A NOVEL FIBROSIS MARKER IN NAFLD REVEALED BY PROTEOMIC ANALYSIS OF SERUM EXTRACELLULAR VESICLES. HEPATOLOGY. 2022. 76. S801-S801
- 坂根 貞嗣, 阪森 亮太郎, 竹原 徹郎. 栄養代謝性肝疾患のマネジメント-栄養・運動・新規治療・発がんリスク 非アルコール性脂肪性肝疾患におけるFadslの意義. 肝臓. 2022. 63. Suppl.1. A40-A40
- 坂根 貞嗣, 巽 智秀, 竹原 徹郎. NAFLD/NASH診療-全身疾患としての位置づけ 非アルコール性脂肪性肝疾患における脂肪組織オートファジー抑制による肝病態改善機序の解明. 肝臓. 2022. 63. Suppl.1. A54-A54
Awards (6)：
- 2024/05 - 2024 Twelfth Annual UC San Diego Department of Surgery Research Symposium Best Poster Presentation for Clinical/HSR/Education Research
- 2022/10 - The Japan Society of Hepatology Kanmuri Award (7th Gilead Sciences Award)
- 2022/02 - 第41回アルコール医学生物学研究会学術集会 優秀演題賞
- 2020/09 - Kansai Liver Club 2020 Best Presentation Award
- 2018/07 - The 5th Liver, Diabetes and Metabolism Forum Young investigator award
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