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J-GLOBAL ID：202101017057139130 Update date: Jul. 25, 2024

Ochiai Tsubasa

オチアイツバサ | Ochiai Tsubasa

Affiliation and department：
Job title： Assistant professor

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (3)：長鎖アシルCoA合成酵素4 , プロスタグランジン , 生理活性脂質

Research theme for competitive and other funds (1)：

2022 - 2024 Analysis on the function of prostacyclin synthase expressed in macrophages in inflammatory diseases

Papers (8)：

Tsubasa Ochiai, Toshiya Honsawa, Keishi Yamaguchi, Yuka Sasaki, Chieko Yokoyama, Hiroshi Kuwata, Shuntaro Hara. Prostacyclin synthase deficiency exacerbates systemic inflammatory responses in lipopolysaccharide-induced septic shock in mice. Inflammation research. 2024
Hiroshi Kuwata, Eriko Nakatani, Yuki Tomitsuka, Tsubasa Ochiai, Yuka Sasaki, Emiko Yoda, Shuntaro Hara. Deficiency of long-chain acyl-CoA synthetase 4 leads to lipopolysaccharide-induced mortality in a mouse model of septic shock. The FASEB Journal. 2023. 37. 12
Tsubasa Ochiai, Toshiya Honsawa, Yuka Sasaki, Shuntaro Hara. Prostacyclin Synthase as an Ambivalent Regulator of Inflammatory Reactions. Biological and Pharmaceutical Bulletin. 2022. 45. 8. 979-984
Tsubasa Ochiai, Yuka Sasaki, Chieko Yokoyama, Hiroshi Kuwata, Shuntaro Hara. Absence of prostacyclin greatly relieves cyclophosphamide-induced cystitis and bladder pain in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021. 35. 10. e21952
Yuka Sasaki, Hiroshi Kuwata, Moe Akatsu, Yuri Yamakawa, Tsubasa Ochiai, Emiko Yoda, Yoshihito Nakatani, Chieko Yokoyama, Shuntaro Hara. Involvement of prostacyclin synthase in high-fat-diet-induced obesity. Prostaglandins & other lipid mediators. 2021. 153. 106523-106523

MISC (38)：

安田美羽, 大林翼, 前本佑樹, 小瀬章太郎, 落合翔, 鈴木健裕, 堂前直, 原俊太郎, 伊藤昭博. アシルCoA合成酵素FATP2のリジン長鎖アシル化の解析. 脂質生化学研究. 2024. 66
小瀬章太郎, 前本佑樹, 大林翼, 落合翔, 鈴木健裕, 堂前直, 原俊太郎, 伊藤昭博. リジン長鎖アシル化によるアシルCoA合成酵素ACSL4の機能調節. 脂質生化学研究. 2024. 66
田宮結, 落合翔, 桑田浩, 原俊太郎. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is involved in the pathogenesis of in the colon diseases. 日本薬学会年会要旨集(Web). 2024. 144th
本沢駿弥, 落合翔, 山口慧士, 桑田浩, 横山知永子, 原俊太郎. Role of Prostacyclin synthase in lipopolysaccharide-induced sepsis in vivo. 日本薬学会年会要旨集(Web). 2024. 144th
佐々木由香, 落合翔, 遠藤勇気, 鈴木康友, 近藤幸尋, 原俊太郎. Role of microsomal prostaglandin E synthase (mPGES)-1 in chemical-induced bladder cacrinogenesis. 日本薬学会年会要旨集(Web). 2024. 144th

Lectures and oral presentations (18)：

アシルCoA合成酵素FATP2のリジン長鎖アシル化の解析
(第66回日本脂質生化学会 2024)
リジン長鎖アシル化によるアシルCoA合成酵素ACSL4の機能調節
(第66回日本脂質生化学会 2024)
長鎖アシルCoA合成酵素-4 (ACSL4) は大腸疾患形成に対し促進的に関与する
(日本薬学会第144回年会 2024)
リポ多糖誘導敗血症におけるプロスタサイクリン合成酵素の機能解析
(日本薬学会第144回年会 2024)
アシルCoA合成酵素ACSL4のリジン長鎖アシル化による機能変換
(第46回日本分子生物学会年会 2023)

Professional career (1)：

Awards (5)：

2022/10 - ONO Pharmaceutical Co., LTD Travel Award at the 17th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
2021/09 - 2021 Japan/Korea joint symposium in pharmaceutical health science and environmental toxicology: poster session, Best Poster Award
2020/09 - 第93回日本生化学会大会若手優秀賞
2019/08 - フォーラム2019: 衛生薬学・環境トキシコロジー優秀若手研究者賞
2015/09 - 第59回日本薬学会関東支部大会優秀口頭発表賞

Association Membership(s) (3)：

日本生化学会 , 日本脂質生化学会 , 日本薬学会

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