Rchr
J-GLOBAL ID：202101017057139130
Update date: Jun. 03, 2024
Ochiai Tsubasa
オチアイ ツバサ | Ochiai Tsubasa
Affiliation and department：
Job title：
Assistant professor
Research field (1)：
Pharmaceuticals - health and biochemistry
Research keywords (3)：
長鎖アシルCoA合成酵素4
, プロスタグランジン
, 生理活性脂質
Research theme for competitive and other funds (1)：
- 2022 - 2024 Analysis on the function of prostacyclin synthase expressed in macrophages in inflammatory diseases
Papers (8)：
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Tsubasa Ochiai, Toshiya Honsawa, Keishi Yamaguchi, Yuka Sasaki, Chieko Yokoyama, Hiroshi Kuwata, Shuntaro Hara. Prostacyclin synthase deficiency exacerbates systemic inflammatory responses in lipopolysaccharide-induced septic shock in mice. Inflammation research. 2024
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Hiroshi Kuwata, Eriko Nakatani, Yuki Tomitsuka, Tsubasa Ochiai, Yuka Sasaki, Emiko Yoda, Shuntaro Hara. Deficiency of long-chain acyl-CoA synthetase 4 leads to lipopolysaccharide-induced mortality in a mouse model of septic shock. The FASEB Journal. 2023. 37. 12
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Tsubasa Ochiai, Toshiya Honsawa, Yuka Sasaki, Shuntaro Hara. Prostacyclin Synthase as an Ambivalent Regulator of Inflammatory Reactions. Biological and Pharmaceutical Bulletin. 2022. 45. 8. 979-984
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Tsubasa Ochiai, Yuka Sasaki, Chieko Yokoyama, Hiroshi Kuwata, Shuntaro Hara. Absence of prostacyclin greatly relieves cyclophosphamide-induced cystitis and bladder pain in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021. 35. 10. e21952
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Yuka Sasaki, Hiroshi Kuwata, Moe Akatsu, Yuri Yamakawa, Tsubasa Ochiai, Emiko Yoda, Yoshihito Nakatani, Chieko Yokoyama, Shuntaro Hara. Involvement of prostacyclin synthase in high-fat-diet-induced obesity. Prostaglandins & other lipid mediators. 2021. 153. 106523-106523
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MISC (31)：
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落合翔, 桑田浩, 原俊太郎. Role of acyl-CoA synthetase long-chain family member 4 in the formation of inflammatory diseases in the colon. 日本薬学会年会要旨集(Web). 2023. 143rd
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佐々木由香, 落合翔, 遠藤勇気, 鈴木康友, 近藤幸尋, 原俊太郎. Role of microsomal prostaglandin E synthase (mPGES)-1 in chemical-induced bladder carcinogenesis. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
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本沢駿弥, 落合翔, 横山知永子, 桑田浩, 原俊太郎. Prostacyclin synthase negatively regulates the inflammatory reactions caused by lipopolysaccharide-induced sepsis in vivo. 衛生薬学・環境トキシコロジー講演要旨集. 2023. 2023
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小瀬章太郎, 前本佑樹, 大林翼, 落合翔, 鈴木健裕, 堂前直, 原俊太郎, 伊藤昭博. Functional conversion of acyl CoA synthase ACSL4 by lysine long-chain acylation. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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大林翼, 前本佑樹, 小瀬章太郎, 落合翔, 鈴木健裕, 堂前直, 原俊太郎, 伊藤昭博. Regulation of lipid metabolism by lysine long-chain acylation of FATP2. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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Lectures and oral presentations (11)：
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腸上皮細胞に発現した長鎖アシルCoA合成酵素4の腸炎誘導大腸がん進展における機能解析
(第96回日本生化学会大会 2023)
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大腸がんの発症・進展における長鎖アシルCoA合成酵素-4の機能解析
(第65回脂質生化学会 2023)
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大腸での炎症性疾患形成における長鎖アシルCoA合成酵素-4の機能解析
(日本薬学会第143回年会 2023)
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Prostacyclin synthase negatively regulates the inflammatory reactions caused by lipopolysaccharide-induced sepsis in vivo
(2023 Japan/Korea joint symposium in pharmaceutical health science and environmental toxicology: poster session 2023)
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Acyl-CoA synthetase long-chain family member 4 (ACSL4) links inflammation and carcinogenesis in a mouse model of colitis-associated cancer
(2023 Japan/Korea joint symposium in pharmaceutical health science and environmental toxicology: poster session 2023)
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Professional career (1)：
- Doctor of philosophy in pharmacy
Awards (5)：
- 2022/10 - ONO Pharmaceutical Co., LTD Travel Award at the 17th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
- 2021/09 - 2021 Japan/Korea joint symposium in pharmaceutical health science and environmental toxicology: poster session, Best Poster Award
- 2020/09 - 第93回日本生化学会大会 若手優秀賞
- 2019/08 - フォーラム2019: 衛生薬学・環境トキシコロジー 優秀若手研究者賞
- 2015/09 - 第59回日本薬学会関東支部大会 優秀口頭発表賞
Association Membership(s) (3)：
日本生化学会
, 日本脂質生化学会
, 日本薬学会
