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J-GLOBAL ID：202101018762614782 Update date: Feb. 11, 2025

Kawashita Eri

カワシタエリ | Kawashita Eri

Affiliation and department：
Job title： Assistant professor

Research field (5)： Molecular biology , Cell biology , Pharmaceuticals - health and biochemistry , Neuroscience - general , Pathobiochemistry

Research keywords (10)：線溶系因子 , α2-アンチプラスミン , ニューロセルピン , 記憶 , 脳老化 , 新生児低酸素性虚血性脳症 , 脳梗塞 , 神経新生 , 神経発達 , セルピン

Research theme for competitive and other funds (8)：

2023 - 2026 Efficient neuronal regeneration in neonatal hypoxic-ischaemic encephalopathy by regulation of extracellular protease activity
2023 - 2025 新生児低酸素性虚血性脳症におけるneuronal replacement効果の向上を目指した細胞外環境整備に関する創薬基盤研究
2021 - 2023 プロテアーゼ活性制御による脳神経再生の高効率化と虚血性脳疾患治療への展開
2018 - 2021 Efficient neuronal regeneration by regulation of protease activity
2017 - 脳神経-血管間の微小環境整備による神経再生の促進

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Papers (31)：

Saki Kishinaka, Eri Kawashita, Taichi Nishizaki, Keiichi Ishihara, Satoshi Akiba. Group IVA phospholipase a<sub>2</sub> in collagen-producing cells promotes high-fat diet-induced infiltration of inflammatory cells into the liver by upregulating the expression of MCP-1. Biological and pharmaceutical bulletin. 2024. 47. 5. 1058-1065
KEIICHI ISHIHARA, RYUTO SAKODA, MASAKO MIZOGUCHI, MITSUGU FUJITA, CHIAMI MOYAMA, YURI OKUTANI, KAZUYUKI TAKATA, MIWA TANAKA, TAKASHI MINAMI, HARUHIKO SAGO, et al. Suppression ofSleeping Beauty-induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome. Anticancer Research. 2024. 44. 2. 489-495
Aina Fukuda, Souichi Nakashima, Yoshimi Oda, Kaneyasu Nishimura, Hidekazu Kawashima, Hiroyuki Kimura, Takashi Ohgita, Eri Kawashita, Keiichi Ishihara, Aoi Hanaki, et al. Plantainoside B in Bacopa monniera binds to Aβ aggregates attenuating neuronal damage and memory deficits induced by Aβ. Biol. Pharm. Bull. 2023. 46. 2. 320-333
Keiichi Ishihara, Eri Kawashita, Satoshi Akiba. Bio-metal dyshomeostasis-associated acceleration of aging and cognitive decline in down syndrome. (Review). Biological & pharmaceutical bulletin. 2023. 46. 9. 1169-1175
Takeyoshi Ozaki, Eri Kawashita, Keiichi Ishihara, Satoshi Akiba. Deficiency of Group IVA Phospholipase A2 in Collagen-Producing Cells Alleviates the Aggravated Hepatic Fibrosis in High-Fat Diet-Fed Mice after Returning to a Normal Diet. Biological & pharmaceutical bulletin. 2023. 46. 3. 488-493

MISC (44)：

西崎太智, 河下映里, 石原慶一, 岸中彩希, 溝田歩美, 秋葉聡. Roles of IVA-type phospholipase A₂ in sinusoidal endothelial cells and hepatic stellate cells in the development of NASH. 日本薬学会年会要旨集(Web). 2024. 144th
川崎真菜, 斉藤美知子, 山川和弘, 河下映里, 秋葉聡, 石原慶一. Roles of Vps26c on copper accumulation in the adult brain of a Down syndrome model mouse. 日本薬学会年会要旨集(Web). 2024. 144th
岡村萌子, 河下映里, 石原慶一, 依馬正次, 松尾理, 秋葉聡. Possible involvement of α2-antiplasmin in cerebrovascular development. 日本薬学会年会要旨集(Web). 2024. 144th
小高春香, 河下映里, 永井信夫, 石原慶一, 西村美紅, 乾菜々子, 松尾理, 秋葉聡. α2-Antiplasmin deficiency enhances the production and migration of neuroblasts after cerebral infarction. 日本薬学会年会要旨集(Web). 2024. 144th
川上陽菜, 千代華歩, 河下映里, 山川和弘, 秋葉聡, 石原慶一. Is brain copper accumulation involved in cognitive dysfunction of Down syndrome model mice models?. 日本薬学会年会要旨集(Web). 2024. 144th

Lectures and oral presentations (17)：

セルピンによる脳機能調節と虚血性脳疾患治療への展開
(第6回Neuro-Vascular 研究会 2023)
Neuroprotective effect of neuroserpin in a mouse model of neonatal hypoxic-ischaemic encephalopathy
(Neuro2022 2022)
Neuroserpin as a promising candidate for neuroprotection in neonatal hypoxic-ischaemic encephalopathy
(Cortical Development Conference 2022)
α2-Antiplasmin as a regulator of adult hippocampal neurogenesis and spatial learning
(Gordon Research Conference: Plasminogen Activation and Extracellular Proteolysis 2020)
α2-Antiplasmin as a potential mediator contributing to cognitive function and brain aging
(The 2nd Joint Meeting of the 24th International Society of Fibrinolysis and Proteolysis and the 17th Plasminogen Activation Workshop 2018)

Education (3)：

2008 - 2011 Pharmaceutical Sciences, Tokushima University
2006 - 2008 Pharmaceutical Sciences
2002 - 2006 The University of Tokushima Faculty of Pharmaceutical Sciences School of Pharmacy

Professional career (1)：

Work history (4)：

2015/07 - 現在 Kyoto Pharmaceutical University Department of Pathological Biochemistry Assistant Professor
2021/10 - 2022/10 University of Oxford Department of Physiology, Anatomy and Genetics
2012/04 - 2015/06 Doshisha Women's College of Liberal Arts Department of Clinical Pathological Biochemistry, Faculty of Pharmaceutical Sciences Assistant Professor
2008/04 - 2012/03 Doshisha Women's College of Liberal Arts Department of Clinical Pathological Biochemistry, Faculty of Pharmaceutical Sciences Research Assistant

Awards (2)：

2018/09 - The 2nd Joint Meeting of the 24th International Society of Fibrinolysis and Proteolysis and the 17th Plasminogen Activation Workshop Travel Award
2011/07 - XXIII Congress of The International Society on Thrombosis and Haemostasis Poster Prize

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