Rchr
J-GLOBAL ID:202201000997999330
Update date: Feb. 03, 2025 MEZAWA YOSHIHIRO
メザワ ヨシヒロ | MEZAWA YOSHIHIRO
Affiliation and department: Homepage URL (1): https://scholar.google.com/citations?user=HD3E1oAAAAAJ&hl=ja&oi=ao Research field (1):
Tumor biology
Research theme for competitive and other funds (3): - 2023 - 2025 大腸癌分子サブタイプが規定する癌間質相互作用の分子メカニズム解明
- 2022 - 2024 乳癌関連線維芽細胞の癌促進的な亜集団を誘導する新規転写因子の探索
- 2020 - 2022 ヒストン脱アセチル化の亢進した癌関連線維芽細胞サブセットの特性解明と治療標的化
Papers (8): -
Hiroya Okazaki, Yoshihiro Mezawa, Yang Shi, Mizuki Sakimoto, Zixu Wang, Akane Ishizuka, Kazunari Yamashita, Asahi Satoh, Yu Koyama, Yuki Fukumura, et al. Expression of Lymphoid Enhancer-Binding Factor 1 in Cancer-Associated Fibroblasts Mediates Tumor Growth and Transdifferentiation Toward Squamous Cell Carcinoma in Human Breast Cancer. Cancer Medicine. 2025. 14. 3
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Yoshihiro Mezawa, Tingwei Wang, Yataro Daigo, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Liying Yang, Reo Maruyama, Hiroyuki Seimiya, et al. Glutamine deficiency drives transforming growth factor-β signaling activation that gives rise to myofibroblastic carcinoma-associated fibroblasts. Cancer science. 2023
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Yu Koyama, Hiroya Okazaki, Yang Shi, Yoshihiro Mezawa, Zixu Wang, Mizuki Sakimoto, Akane Ishizuka, Yasuhiko Ito, Takumi Koyama, Yataro Daigo, et al. Increased RUNX3 expression mediates tumor-promoting ability of human breast cancer-associated fibroblasts. Cancer Medicine. 2023
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Keiko Nishikawa, Yoshihiro Mezawa, Toshiyuki Kobayashi. Bcat1 is controlled by Tsc2/mTORC1 pathway at expression levels and its deficiency together with Bcat2 inactivation suppresses the growth of a Tsc2-/- tumor cell line. Genes to cells. 2023. 28. 6. 447-456
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Yoshihiro Mezawa, Akira Orimo. Phenotypic heterogeneity, stability and plasticity in tumor-promoting carcinoma-associated fibroblasts. The FEBS Journal. 2021. 289. 9. 2429-2447
more... MISC (15): -
岡崎寛弥, 施陽, 咲本瑞来, 小山侑, 小山侑, 王子旭, 石塚朱音, 目澤義弘, 梶野一徳, 片倉朗, et al. Investigation of aberrant LEF1 expression in tumor-promoting cancer-associated fibroblasts. 日本癌学会学術総会抄録集(Web). 2023. 82nd
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Yoshihiro Mezawa, Akira Orimo. The cellular differentiation program in carcinoma cells controlled by carcinoma-associated fibroblasts. 2022. 77. 2. 144-151
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加藤祐子, 目澤義弘, 阿部雅明, 陳経権, 水越幸輔, 水越幸輔, 岡澤裕, 坂本一博, 折茂彰. Generation of experimental CAFs by co-transplantation of colorectal cancer organoids and normal colonic fibroblasts. 日本消化器癌発生学会総会プログラム・抄録集. 2022. 33rd
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目澤 義弘, 醍醐 弥太郎, 高野 淳, 宮城 洋平, 横瀬 智之, 山下 年成, 丸山 玲緒, 清宮 啓之, 折茂 彰. グローバルなヒストン脱アセチル化は癌関連線維芽細胞の筋線維芽細胞性に必須である. 日本癌学会総会記事. 2021. 80回. [J11-1]
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小山 拓洋, 目澤 義弘, 山下 和成, 王 子旭, 高野 淳, 宮城 洋平, 横瀬 智之, 山下 年成, 小山 侑, 菅原 圭亮, et al. FOXO1の発現は、CAFsの活性化された腫瘍促進形質能を仲介します. 日本癌学会総会記事. 2021. 80回. [P14-7]
more... Work history (1): - 2022/04 - 現在 Juntendo University
Association Membership(s) (1):
The Japanese Cancer Association
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