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J-GLOBAL ID：202201003846519556
Update date: Feb. 25, 2025 Horie Tetsuhiro
ホリエ テツヒロ | Horie Tetsuhiro
Kanazawa Medical University Medical Research Institute
About Kanazawa Medical University Medical Research Institute
Job title： Assistant Professor
Research theme for competitive and other funds (5)：
- 2024 - 2027 アポトーシス細胞を活用した変形性膝関節症治療のための新規細胞製剤の開発
- 2022 - 2025 遺伝的不安定性による変異蓄積量を標的とした新規抗がん剤シーズの開発
- 2024 - 2025 バイオインフォマティクスを駆使した肺がん幹細胞の新規治療標的の探索
- 2022 - 2024 In silico解析を活用したEGFRシグナル非依存的な肺がん幹細胞の新規治療標的の探索
- 2019 - 2022 中枢性Erk5シグナルによる肥満調節メカニズムの解明
- Yu Kato, Takeshi Inaba, Koudai Shinke, Noriko Hiramatsu, Tetsuhiro Horie, Takuya Sakamoto, Yuko Hata, Eiji Sugihara, Tetsuya Takimoto, Noriaki Nagai, et al. Comprehensive Search for Genes Involved in Thalidomide Teratogenicity Using Early Differentiation Models of Human Induced Pluripotent Stem Cells: Potential Applications in Reproductive and Developmental Toxicity Testing. Cells. 2025
- Shigeru Sugiki, Tetsuhiro Horie, Kenshiro Kunii, Takuya Sakamoto, Yuka Nakamura, Ippei Chikazawa, Nobuyo Morita, Yasuhito Ishigaki, Katsuhito Miyazawa. Integrated Bioinformatic Analyses Reveal Thioredoxin as a Putative Marker of Cancer Stem Cells and Prognosis in Prostate Cancer. Cancer Informatics. 2025
- Tetsuhiro Horie, Hiroaki Hirata, Takuya Sakamoto, Hironori Kitajima, Atsushi Fuku, Yuka Nakamura, Yumi Sunatani, Ikuhiro Tanida, Hiroshi Sunami, Yoshiyuki Tachi, et al. Multiomics analyses reveal adipose-derived stem cells inhibit the inflammatory response of M1-like macrophages through secreting lactate. Stem cell research & therapy. 2024. 15. 1. 485-485
- Koki Sadamori, Takuya Kubo, Tomoki Yoshida, Megumi Yamamoto, Yui Shibata, Kazuya Fukasawa, Kazuya Tokumura, Tetsuhiro Horie, Takuya Kadota, Ryotaro Yamakawa, et al. CDK8 inhibitor KY-065 rescues skeletal abnormalities in achondroplasia model mice. Biochimica et biophysica acta. Molecular basis of disease. 2024. 167626-167626
- Takuya Sakamoto, Atsushi Fuku, Tetsuhiro Horie, Hironori Kitajima, Yuka Nakamura, Ikuhiro Tanida, Hiroshi Sunami, Hiroaki Hirata, Yoshiyuki Tachi, Yasuo Iida, et al. A novel cell source for therapy of knee osteoarthritis using atelocollagen microsphere-adhered adipose-derived stem cells: Impact of synovial fluid exposure on cell activity. Regenerative Therapy. 2024
- 岡山靖佳, 落合信介, 堀江哲寛, 家崎高志, 深澤和也, 鎌倉昌樹, 池野久美子, 永松剛, 檜井栄一. Daily oral intake of Royal Jelly prevents cartilage degeneration in osteoarthritis model mice. 日本薬学会年会要旨集(Web). 2022. 142nd
- 鈴木紅音, 深澤和也, 堀江哲寛, 村田美怜, 小林正輝, 檜井栄一. ERK5 controls stemness and tumorigenicity of glioma stem cells by regulating the STAT3 signaling. 日本薬学会年会要旨集(Web). 2022. 142nd
- 山田孝紀, 深澤和也, 堀江哲寛, 徳村和也, 岩橋咲幸, 家崎高志, 檜井栄一, 檜井栄一. 加齢に伴う骨恒常性維持機能の低下における間葉系幹細胞のCDK8の役割. 日本薬理学雑誌. 2021. 156. Supplement
- Fukasawa Kazuya, Yamada Takanori, Horie Tetsuhiro, Hiraiwa Manami, Kaneda Katsuyuki, Hirao Atsushi, Hinoi Eiichi. Osteoblastic mTORC1 accelerates acute myeloid leukemia growth via IL-6 signaling. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2020. 93. 0. 1-SS-53
- 堀江哲寛, 家崎高志, 深澤和也, 金田勝幸, 檜井栄一. mTORC1/Sox9シグナルによる間葉系前駆細胞の機能調節. 日本再生医療学会総会(Web). 2019. 18th
- Development of anti-cancer drugs targeting mRNA abnormalities
2023
-
がんの親玉「がん幹細胞」の謎に迫る!
(第38回北國がん基金助成金贈呈式・市民公開講座 2024) -
脂肪由来幹細胞のメタボライトによる免疫抑制機構の解明
(日本生化学会北陸支部第41回大会 2023) -
間葉系幹細胞に発現するErk5が骨恒常性維持に与える影響
(日本生化学会北陸支部第40回大会 2022) -
Erk5 in mesenchymal stem cells maintains bone homeostasis in adulthood
(2022) -
中枢性Erk5がエネルギー代謝調節に与える影響
(日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019 2019)
- 2019 - 2022 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science
- 2019 - 2019 Kanazawa University Graduate School of Medical Science Division of Pharmaceutical Sciences
- 2017 - 2019 Kanazawa University Graduate School of Medical Science Division of Pharmaceutical Sciences
- 2013 - 2017 Kanazawa University College of Medical Pharmaceutical and Health Sciences School of Pharmaceutical Sciences
- Ph.D. (Pharmaceutical Sciences) (Gifu Pharmaceutical University)
- 2022/04 - 現在 Kanazawa Medical University Medical Research Institute Assistant Professor
- 2019/04 - 2022/03 JSPS Research Fellowship for Young Scientists
- 2024/03 - 金沢医科大学総合医学研究所 金沢医科大学総合医学研究所 令和5年度研究セミナー ベストポスター賞
- 2023/03 - Kanazawa Medical University Medical Research Institute Director's award
- 2019/11 - Tokai Branch of The Pharmaceutical Society of Japan Best presentation award
- 2018/03 - The Pharmaceutical Society of Japan Student presentation award
- 2017/11 - Hokuriku Branch of The Pharmaceutical Society of Japan Student presentation award
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