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J-GLOBAL ID:202201006426611553   Update date: Feb. 14, 2025

Iijima Hirotaka

イイジマ ヒロタカ | Iijima Hirotaka
Clips
Affiliation and department:
Job title: Assistant Professor
Other affiliations (2):
  • Discovery Center for Musculoskeletal Recovery, Schoen Adams Research Institute at Spaulding  Research Faculty
  • Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital  Research Faculty
Homepage URL  (1): https://connects.catalyst.harvard.edu/Profiles/display/Person/217832
Research field  (11): Statistical science ,  Nanobioscience ,  Medical equipment testing ,  Systems genomics ,  Nutrition and health science ,  Computational science ,  Biological, health, and medical informatics ,  Orthopedics ,  Molecular biology ,  Biomedical engineering ,  Rehabilitation science
Research keywords  (7): Extracellular Vesicles ,  Exercise Physiology ,  Rehabilitation Medicine ,  Aging ,  Mechanobiology ,  Computational Genomics ,  Network Medicine
Research theme for competitive and other funds  (10):
  • 2024 - 2029 Gender and sex dimorphism in age-related knee osteoarthritis
  • 2024 - 2029 The opposing effects of matrix aging and muscle activity on extracellular vesicle promotion of muscle regeneration
  • 2023 - 2027 力学的記憶を標的とする新規変形性関節症治療戦略の確立
  • 2022 - 2027 Investigation of epigenetic regulatory mechanism driving age-related diseases
  • 2021 - 2022 抗老化因子クロトーに着目した変形性関節症の病態解明
Show all
Papers (115):
  • Gabrielle Gilmer, Hirotaka Iijima, Zachary R Hettinger, Natalie Jackson, Juliana Bergmann, Allison C Bean, Nafiseh Shahshahan, Ekaterina Creed, Rylee Kopchak, Kai Wang, et al. Menopause-induced 17β-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage. Nature aging. 2025
  • Hirotaka Iijima, Fabrisia Ambrosio, Yusuke Matsui. Network-based systematic dissection of exercise-induced inhibition of myosteatosis in older individuals. The Journal of physiology. 2025. 603. 1. 45-67
  • Sora Kawabata, Hirotaka Iijima, Naohiko Kanemura, Kenji Murata. Genome-Wide Network Analysis of DRG-Sciatic Nerve Network-Inferred Cellular Senescence and Senescence Phenotype in Peripheral Sensory Neurons. Molecular neurobiology. 2024
  • Iijima H, Ambrosio F. Network medicine as a tool to enhance regenerative rehabilitation practice. Am J Phys Med Rehabil (accepted). 2024
  • Yamagata M, Kimura T, Chang AH, Iijima H. Sex differences in ambulatory biomechanics: a meta-analysis providing a mechanistic insight into knee osteoarthritis. Medicine & Science in Sports & Exercise (accepted). 2024. 57. 1. 144-153
more...
MISC (8):
  • 関節軟骨の加齢変化から紐解く変形性関節症の病態. 2024
  • The Royal Correspondence of the Assyrian Empire. INFORMATION Activities & News. 2023
  • 飯島 弘貴. 変形性膝関節症におけるメカニカルストレス研究と間葉系幹細胞治療後の再生リハビリテーション. 日本基礎理学療法学雑誌. 2019. 22. 1. 1-8
  • 中畑 晶博, 飯島 弘貴, 伊藤 明良, 王 天舒, 中原 峻, 張 ジュエ, 久保 奈央子, 河合 秀紀, 青山 朋樹, 黒木 裕士. 膝半月不安定化による膝蓋大腿関節軟骨損傷と歩行キネマティクスの関係. 理学療法学. 2019. 46. Suppl.1. O5-6
  • 飯島 弘貴. 【運動ってなんだ?"Exercise is Medicine"を支えるサイエンスを拓く】変形性膝関節症軟骨におけるメカニカルストレス研究 運動の強度依存的な軟骨保護・破壊作用とその分子メカニズム探求の挑戦. 実験医学. 2019. 37. 8. 1240-1245
more...
Patents (1):
  • Methods and materials for treating osteoarthritis
Books (1):
  • サプリメントの機能性:運動器・スポーツ
    メジカルビュー社 2015
Lectures and oral presentations  (170):
  • Ultrasonography and magnetic resonance imaging revealed female-specific joint structural abnormalities in early knee osteoarthritis
    (ORS2025 2025)
  • Echo intensity and texture analysis in vastus medialis: complementary predictors of early knee osteoarthritis
    (ORS2025 2025)
  • Network medicine-based approach to predict combinational benefits of multi-modal rehabilitation program on cartilage health
    (ORS2025 2025)
  • A meta-analysis to interrogate skeletal muscle anabolic response to resistance exercise protocol
    (ORS2025 2025)
  • A network meta-analysis of rehabilitation strategies to maximize clinical outcomes in individuals with knee osteoarthritis
    (ORS2025 2025)
more...
Education (3):
  • 2014 - 2017 Kyoto University Graduate School of Medicine Human Health Sciences, Doctor Course
  • 2012 - 2014 Kyoto University Graduate School of Medicine Human Health Sciences, Master Course
  • 2005 - 2009 Saitama Prefectural University School of Health and Social Services Department of Physical Therapy
Professional career (1):
  • PhD (Human Health Science) (Kyoto University)
Work history (13):
  • 2024/06 - 現在 Department of Physical Medicine & Rehabilitation, Harvard Medical School Assistant Professor
  • 2023/10 - 現在 Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital Research Faculty
  • 2023/10 - 現在 Discovery Center for Musculoskeletal Recovery, Schoen Adams Research Institute at Spaulding Research Faculty
  • 2023/10 - 2024/05 Department of Physical Medicine & Rehabilitation, Harvard Medical School Member of the Faculty
  • 2023/10 - 2024/03 Biomedical and Health Informatics Unit, Graduate School of Medicine, Nagoya University 客員研究者
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Committee career (5):
  • 2024/11 - 現在 The Journals of Gerontology: Series A Editorial Board Member
  • 2024/07 - 現在 The Journal of Physiology Editorial Board Member
  • 2024/05 - 現在 Mass General Brigham Sex/gender Informed Research Collaborative Think Tank (SIRCTT) Advisory committee member
  • 2020 - 現在 Journal of Visualized Experiments Guest Editor
  • 2022/04 - 2022/10 名古屋大学 世界的課題を解決する知の「開拓者」育成事業 リトリート合宿 幹事
Awards (15):
  • 2024/05 - Mass General Brigham Commercialization & Inclusive Leadership Program (CILP) Fellowship
  • 2024/04 - Editorla Board Fellowship, The Journal of Physiology
  • 2024/04 - The United Japanese Researcher Around the World Outstanding Research Paper Award
  • 2024/03 - Poster award (3rd; co-presenter), The 10th Annual International Symposium on Regenerative Rehabilitation Menopause-induced chondrocyte senescence and matrix disassembly compromises cartilage integrity
  • 2024/03 - Poster award (2nd; co-presenter), The 10th Annual International Symposium on Regenerative Rehabilitation The Good Fat: Youthful infrapatellar fat pads enhance mitochondrial efficiency to restore aging chondrocyte extracellular matrix production
Show all
Association Membership(s) (12):
International Society for Computational Biology ,  Association of Academic Physiatrist Regenerative Rehabilitation Consortium ,  Association of Academic Physiatrist ,  American College of Sports Medicine ,  American Society of Neurorehabilitation ,  Orthopaedic Research Society ,  Osteoarthritis Research Society International (OARSI) ,  公益社団法人 日本理学療法士協会 ,  日本軟骨代謝学会 ,  The Society of Life Support Engineering ,  American Physiological Society ,  一般社団法人 日本機械学会
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