Rchr
J-GLOBAL ID:202201007981042110   Update date: Sep. 11, 2024

Matsuo Hirotaka

マツオ ヒロタカ | Matsuo Hirotaka
Affiliation and department:
Job title: Chief Researcher
Research field  (1): Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds  (4):
  • 2023 - 2028 持続可能な薬用植物の生産基盤技術開発及び産地形成に関する研究
  • 2021 - 2024 新規メカニズムを有する抗癌剤創薬を指向した上皮間葉転換誘導細胞増殖阻害物質の創出
  • 2019 - 2021 Establishment of screening for novel sulfur-containing metabolites by selective oxidation of sulfur atom combined liquid chromatography-mass spectrometry
  • 2017 - 2019 The search for novel metabolites from microorganisms by physicochemical screening
Papers (39):
  • Hirotaka Matsuo, Hitomi Kawakami, Yuka Otsuki, Chieto Miyashita, Nobuo Kawahara, Hiroyuki Fuchino, Kayo Yoshimatsu. Utilization of Inedible Parts of Aralia cordata with High-Content Chlorogenic Acid Cultivated in Tokyo. Sustainability. 2024. 16. 6. 2582-2582
  • Hirotaka Matsuo, Hitomi Kawakami, Naoko Anjiki, Noriaki Kawano, Hiroyuki Fuchino, Nobuo Kawahara, Kayo Yoshimatsu. Screening of growth inhibitors for epithelial-mesenchymal transition-induced cells by TGF-β from plant-based sources identified the active compound hydroxychavicol from Piper bitle. Journal of natural medicines. 2024
  • Nattaporn Klykleung, Hirotaka Matsuo, equal contribution, Masato Iwatsuki, Yoko Takahashi, Satoshi Omura, Masahiro Yuki, Takuji Kudo, Moriya Ohkuma, Rataya Luechapudiporn, et al. Genomic analysis and physicochemical screening of ikarugamycin, fumaquinone, and a new compound, pudicin from Streptomyces sp. 3MP-14. ScienceAsia. 2023. 49. 5. 661-669
  • Yuto Hirata, Katsumi Shigemura, Michika Moriwaki, Masato Iwatsuki, Yuki Kan, Tooru Ooya, Koki Maeda, Youngmin Yang, Takuji Nakashima, Hirotaka Matsuo, et al. Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo. Cancers. 2023. 15. 10
  • Rei Miyano, Hirotaka Matsuo, Takayuki Mokudai, Mayuka Higo, Kenichi Nonaka, Yoshimi Niwano, Kazuro Shiomi, Yōko Takahashi, Satoshi Ōmura, Takuji Nakashima. New nitrogen-compounds, penicidones E and F, produced by the fungal strain Oidiodendron sp. FKI-7498. Bioscience, biotechnology, and biochemistry. 2022. 87. 1. 38-44
more...
MISC (12):
  • 松尾洋孝, 河上仁美, 大槻優華, 宮下智人, 渕野裕之, 川原信夫, 川原信夫, 吉松嘉代. 東京都産ウド根の有用性に関する研究. 日本生薬学会年会講演要旨集. 2022. 68th
  • 三浦 悠花, 松尾 洋孝, 中島 琢自, 片岡 孝夫, 大西 素子, 木村 賢一. 琥珀と微生物由来の生物活性物質のPPM1A活性化作用とRBL-2H3細胞での脱顆粒抑制活性との関連性. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [2Z05-697)]
  • 松尾 洋孝, 中島 琢自. エルゴステロール修飾シリカ(ESシリカ)を用いた新規物質の探索-The search for new compounds using ergosterol modified silica (ES silica). Research communications = 発酵研究所研究報告. 2020. 34. 111-120
  • 松尾 洋孝, 中島 琢自. 質量分析による新規物質の探索-The search for new compounds by mass spectrometry. Research communications = 発酵研究所研究報告. 2020. 34. 75-92
  • 松尾 洋孝, 中島 琢自. 質量分析および主成分分析を利用した探索系による含窒素物質の探索-Screening for nitrogen compounds by principle component analysis with liquid chromatography-mass spectrometry. Research communications = 発酵研究所研究報告. 2020. 34. 93-100
more...
Patents (2):
  • 新規ポコニオライド化合物及びその使用
  • 新規ナナオマイシンH化合物及びその誘導体、並びに、それらを有効成分として含有する上皮間葉転換が誘導された細胞に傷害を与える薬剤
Education (1):
  • 2011 - 2016 Ritsumeikan University Graduate School of Science and Engineering Science and Engineering Major
Professional career (1):
  • Science (Ritsumeikan University)
Work history (6):
  • 2023/04 - 現在 Osaka University Graduate School of Pharmaceutical Sciences
  • 2023/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition
  • 2022/04 - 現在 University of Tsukuba School of Integrative and Global Majors Associate Professor
  • 2020/04 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition Research Center for Medicinal Plant Resources Researcher
  • 2015/04 - 2020/03 Kitasato University Omura Satoshi Memorial Institute
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Awards (1):
  • 2022/06 - 日本薬学会・生薬天然物部会 奨励研究賞
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