Fujii Kiyonaga

フジイキヨナガ | Fujii Kiyonaga

Affiliation and department：
Job title： Professor

Research field (1)： Pharmaceuticals - analytical and physicochemistry

Research keywords (5)：分離科学 , 質量分析 , プロテオミクス , バイオマーカー , 天然物化学

Research theme for competitive and other funds (7)：

2020 - 2023 膵臓がんの頑健性の分子基盤の解明とその破壊による新規治療法の確立
2020 - 2023 リボフラビン経路を標的とした新規膵臓がん治療法の開発
2015 - 2017 Critical mechanisms for the determination of hepatocytic and bile ductular differentiation
2012 - 2016 Mutual plasticity between hepatocytes and bile ductular cells in ductular reaction - its significance and therapeutic implications
2013 - 2015 Hepaocyte injury induced by iron overload and its application for isolation of bile duct cells and stem cells

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Papers (81)：

Takayuki Koga, Kie Inoue, Fuka Hirayama, Makoto Hiromura, Kiyonaga Fujii, Yuji Ishii, Masayo Hirao-Suzuki, Shuso Takeda, Akihisa Toda, Fumio Soeda. Dimethylglycine, a methionine metabolite, participates in the suppressive effect of methionine on 1-fluoro-2,4-dinitrobenzene-induced dermatitis. Biological & pharmaceutical bulletin. 2023
Genki Sakai, Masayo Hirao-Suzuki, Takayuki Koga, Takananobu Kobayashi, Jun Kamishikiryo, Michitaka Tanaka, Kiyonaga Fujii, Masufumi Takiguchi, Narumi Sugihara, Akihisa Toda, et al. Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration. Journal of Toxicological Sciences. 2022. 47. 4. 159-168
Hiroki Sakai, Hiroyuki Kimura, Kanji Otsubo, Tomoyuki Miyazawa, Hideki Marushima, Koji Kojima, Motohiro Chosokabe, Naoki Furuya, Junki Koike, Kiyonaga Fujii, et al. Minichromosome maintenance 2 is an independent predictor of survival in patients with lung adenocarcinoma. Molecular and Clinical Oncology. 2022. 16. 1. 22-22
Toshihide Nishimura, Kiyonaga Fujii, Haruhiko Nakamura, Saeko Naruki, Hiroki Sakai, Hiroyuki Kimura, Tomoyuki Miyazawa, Masayuki Takagi, Naoki Furuya, Gyorgy Marko-Varga, et al. Protein co-expression network-based profiles revealed from laser-microdissected cancerous cells of lung squamous-cell carcinomas. Scientific Reports. 2021. 11. 1. 20209-20209
Hidetomo Yokoo, Norihito Shibata, Akinori Endo, Takahito Ito, Yuta Yanase, Yuki Murakami, Kiyonaga Fujii, Kengo Hamamura, Yasushi Saeki, Mikihiko Naito, et al. Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via in Silico Design. Journal of Medicinal Chemistry. 2021. 64. 21. 15868-15882

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MISC (3)：

田村奈月美, 小西純, 藤井清永, 浜村賢吾, 横尾英知, 柴田識人, 内藤幹彦, 出水庸介, 有竹浩介. 造血器型プロスタグランジンD合成酵素分解誘導薬の創出-酵素阻害薬に対する優位性について-. 日本薬学会九州山口支部大会講演要旨集(CD-ROM). 2023. 40th
柴田識人, 横尾英知, 遠藤彬則, 伊藤貴仁, 柳瀬雄太, 柳瀬雄太, 村上優貴, 村上優貴, 藤井清永, 近藤一成, et al. Development of a selective degrader targeting hematopoietic prostaglandin D synthase. 日本薬学会年会要旨集(Web). 2022. 142nd
横尾英知, 柴田識人, 永沼美弥子, 村上優貴, 藤井清永, 伊藤貴仁, 有竹浩介, 内藤幹彦, 出水庸介. 造血器型プロスタグランジンD合成酵素分解誘導剤の開発. 日本薬学会年会要旨集. 2021. 141年会. 28V06-am11

Education (2)：

- 1995 Meijo University Graduate School of Pharmacy
- 1993 Meijo University Faculty of Pharmacy Department of Pharmacy

Professional career (2)：

Ph. D. (The University of Tokushima)
Master of Pharmaceutical Sciences (Meijo University)

Work history (8)：

2019 - Daiichi University of Pharmacy
2016 - St.Marianna University School of Medicine
2013 - Asahikawa Medical University
2006 - Hokkaido University Faculty of Pharmaceutical Sciences
2005 - National Cancer Center

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Association Membership(s) (4)：

日本分析学会 , 日本癌学会 , 日本質量分析学会 , 日本薬学会

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