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J-GLOBAL ID：202201010429286910   Update date: Apr. 08, 2025

Ohba Yohsuke

オオバ ヨウスケ | Ohba Yohsuke
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Affiliation and department：
Keio University Faculty of Pharmacy Department of Pharmacy

About Keio University Faculty of Pharmacy Department of Pharmacy


Job title： Assistant Professor/Senior Assistant Professor
Research field  (1)： Cell biology
Research keywords  (3)： 脂質輸送タンパク質 ,  リン脂質 ,  ミトコンドリア
Research theme for competitive and other funds  (2)：
  • 2023 - 2026 膜脂質環境によるミトコンドリアプロテアーゼ活性制御機構の解明
  • 2021 - 2024 ポストリソソームシグナルを駆動する脂質因子の解析
Papers (7)：
  • Ohba Y., Motohashi M., Arita M. Characterization of UGT8 as a monogalactosyl diacylglycerol synthase in mammals. The journal of Biochemistry. 2024
  • Wang J., Taki M., Ohba Y., Arita M., Yamaguchi S. Fluorescence Lifetime Imaging of Lipid Heterogeneity in the Inner Mitochondrial Membrane with a Super-photostable Environment-Sensitive Probe. Angewandte Chemie - International Edition. 2024. 63. 28
  • M Patron, D Tarasenko, H Nolte, L Kroczek, M Ghosh, Y Ohba, Y Lasarzewski, ZA Ahmadi, A Cabrera-Orefice, A Eyiama, et al. Regulation of mitochondrial proteostasis by the proton gradient. The EMBO Journal. 2022. 41. 16. e110476
  • MacVicar, T., Ohba, Y., Nolte, H., Mayer, F.C., Tatsuta, T., Sprenger, HG, Lindner, B., Zhao, Y., Li, J., Bruns, C., et al. Lipid signaling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019. 575. 361-365
  • Saita, S., Tatsuta, T., Lampe, A.P., König, T., Ohba, Y., Langer, T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. The EMBO Journal. 2018. e97909
ｍore...
MISC (4)：
  • Ohba, Y., MacVicar, T., Langer, T. Regulation of mitochondrial plasticity by the i-AAA protease YME1L. Biological Chemistry. 2020. 401. 877-890
  • 大場陽介. 酸素欠乏によるミトコンドリアタンパク質のリプログラミング. 実験医学. 2020. 38. 995-998
  • 大場陽介, 河野望, 新井洋由. リン脂質脂肪酸鎖メタボロームと代謝疾患. 内分泌・糖尿病・代謝内科. 2015. 41. 341-346
  • 大場陽介, 河野望. 脂質異常とオルガネラストレス. 医学のあゆみ. 2015. 245. 382-388
Education (3)：
  • 2012 - 2015 The University of Tokyo 薬学系研究科
  • 2010 - 2012 The University of Tokyo 薬学系研究科
  • 2006 - 2010 The University of Tokyo Pharmaceutical Sciences 薬学科
Professional career (1)：
  • 博士(薬科学) (東京大学)
Work history (4)：
  • 2022/05 - 現在 慶應義塾大学 薬学部 専任講師
  • 2020/10 - 2022/04 武田薬品工業 研究員
  • 2016/02 - 2020/09 Max Planck Institute for Biology of Ageing ポストドクトラルフェロー
  • 2015/04 - 2016/01 東京大学 薬学系研究科 助教
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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