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J-GLOBAL ID:202201010731282672   Update date: Dec. 16, 2024

Murata Kenji

ムラタ ケンジ | Murata Kenji
Affiliation and department:
Research field  (3): Orthopedics ,  Immunology ,  Molecular biology
Research keywords  (4): 養子免疫療法 ,  T細胞受容体 ,  腫瘍免疫学 ,  骨軟部肉腫
Research theme for competitive and other funds  (3):
  • 2021 - 2023 抗肉腫ヒト人工T細胞療法に向けたTCR・抗原ペア網羅的解析プラットフォーム開発
  • 2022 - 2023 腫瘍反応性TCRをプローブとして用いた新たな肉腫抗原同定法の開発
  • 2020 - 2022 Immune response of tumor-infiltrating T lymphocytes in sarcoma using single-cell analysis
Papers (48):
  • Kanta Hori, Shuhei Yamada, Kenji Murata, Haruka Miyata, Yuka Mizue, Aiko Murai, Tomoyuki Minowa, Kenta Sasaki, Naoki Shijubou, Terufumi Kubo, et al. Establishment of potent TCR-T cells specific for cisplatin-resistance related tumor-associated antigen, CLSPN using codon-optimization. Human vaccines & immunotherapeutics. 2024. 20. 1. 2414542-2414542
  • Minami Fusagawa, Serina Tokita, Kenji Murata, Tasuku Mariya, Mina Umemoto, Shintaro Sugita, Kazuhiko Matsuo, Yoshihiko Hirohashi, Tsuyoshi Saito, Takayuki Kanaseki, et al. Identification and phenotypic characterization of neoantigen-specific cytotoxic CD4+ T cells in endometrial cancer. Cancer Immunology Research. 2024
  • Tomoyuki Minowa, Kenji Murata, Yuka Mizue, Aiko Murai, Munehide Nakatsugawa, Kenta Sasaki, Serina Tokita, Terufumi Kubo, Takayuki Kanaseki, Tomohide Tsukahara, et al. Single-cell profiling of acral melanoma infiltrating lymphocytes reveals a suppressive tumor microenvironment. Science translational medicine. 2024. 16. 776. eadk8832
  • Tomohide Shirosaki, Noriko Kawai, Yuma Ebihara, Aiko Murai, Terufumi Kubo, Rena Morita, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Toshiaki Shichinohe, et al. Aldehyde Dehydrogenese-1 High Cancer Stem-like Cells/Cancer-initiating Cells Escape from Cytotoxic T Lymphocytes due to Lower Expression of Human Leukocyte Antigen Class 1. Anticancer research. 2024. 44. 5. 1877-1883
  • Terufumi Kubo, Shiori Asano, Kenta Sasaki, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Toshihiko Torigoe. Assessment of cancer cell-expressed HLA class I molecules and their immunopathological implications. HLA. 2024. 103. 5. e15472
more...
MISC (8):
  • 水江由佳, 廣橋良彦, 塚原智英, 金関貴幸, 久保輝文, 村田憲治, 鳥越俊彦. Development of HLA-A2/Claspin peptide-specific antibodies targeting platinum-resistant cancer cells. 日本病理学会会誌. 2023. 112. 1
  • 箕輪智幸, 箕輪智幸, 村田憲治, 廣橋良彦, 宇原久, 鳥越俊彦. Comprehensive single-cell immune profiling of tumor-infiltrating lymphocytes in acral melanoma. 日本病理学会会誌. 2023. 112. 1
  • 箕輪智幸, 廣橋良彦, 村田憲治, 久保輝文, 鳥越俊彦. Cell fusion with melanoma and macrophage contribute to the immune escape. 日本病理学会会誌. 2022. 111. 1
  • 廣橋良彦, 久保輝文, 村田憲治, 金関貴幸, 塚原智英, 鳥越俊彦. Roles of tumor microenvironment in cancer immunity. 日本病理学会会誌. 2022. 111. 1
  • 時田芹奈, 時田芹奈, 金関貴幸, 村田憲治, 中津川宗秀, 平間知美, 平間知美, 佐藤昇志, 佐藤昇志, 秦史壯, et al. Neoantigen identification and reactive TCR analysis in CRC tissue using a proteogenomic approach. 日本病理学会会誌. 2022. 111. 1
more...
Books (1):
  • 次世代CAR-T細胞
    羊土社 2023 ISBN:9784758125734
Work history (4):
  • 2023/11 - 現在 Sapporo Medical University
  • 2022/06 - 2023/10 Sapporo Medical University Research Institute for Frontier Medicine
  • 2020/04 - 2022/05 Sapporo Medical University
  • 2016/04 - 2020/03 プリンセスマーガレットがんセンター 平野研究室 博士研究員
Awards (1):
  • 2018 - Research award Identification of a novel human T cell population with the characteristics of stem-like chemo-resistance.
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