Toriuchi Kohki

トリウチコウキ | Toriuchi Kohki

Affiliation and department：

Research field (3)： Neuropathology , Clinical pharmacy , Fetal medicine/Pediatrics

Research keywords (11)：小児神経発達 , 神経保護 , 神経再生 , グリア , グリア-ニューロンクロストーク , 脳虚血 , 細胞老化 , 低酸素 , 代謝シグナル , 血液脳関門 , 血管内皮細胞

Research theme for competitive and other funds (4)：

2023 - 2025 グリア瘢痕における細胞老化を標的とした新生児低酸素性虚血性脳症の予後改善治療
2022 - 2024 ミトコンドリアダイナミクスによるグリア活性化メカニズムの解明と脳保護治療への応用
2022 - 2024 DNAメチル化状態に着目した神経芽腫に対する新規治療法の創出
2021 - 2022 代謝センサーAMPKのグリア制御による新生児低酸素性虚血性脳症への新規脳保護治療

Papers (12)：

Satoru Takeshita, Hiroki Kakita, Nami Nakamura, Mari Mori, Kohki Toriuchi, Hiromasa Aoki, Yasumichi Inoue, Hidetoshi Hayashi, Yasumasa Yamada, Mineyoshi Aoyama. Thrombopoietin exerts a neuroprotective effect by inhibiting the suppression of neuronal proliferation and axonal outgrowth in intrauterine growth restriction rats. Experimental Neurology. 2024. 377. 114781-114781
Mai Nagasaka, Chiharu Miyajima, Yasumichi Inoue, Sakura Hashiguchi, Yuya Suzuki, Daisuke Morishita, Hiromasa Aoki, Kohki Toriuchi, Ryohei Katayama, Mineyoshi Aoyama, et al. ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis. Biochemical and Biophysical Research Communications. 2024. 149789-149789
Naoya Fukuda*, Kohki Toriuchi*, Rina Mimoto, Hiromasa Aoki, Hiroki Kakita, Yoshiaki Suzuki, Satoru Takeshita, Tetsuya Tamura, Hisao Yamamura, Yasumichi Inoue, et al. Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4. Neurochemical Research. 2023. 49. 3. 800-813
Reina Owaki, Hiromasa Aoki, Kohki Toriuchi, Yasumichi Inoue, Hidetoshi Hayashi, Satoru Takeshita, Hiroki Kakita, Yasumasa Yamada, Mineyoshi Aoyama. AMPK activators suppress cholesterol accumulation in macrophages via suppression of the mTOR pathway. Experimental cell research. 2023. 113784-113784
Kohki Toriuchi*, Toshie Kihara*, Hiromasa Aoki, Hiroki Kakita, Satoru Takeshita, Hiroko Ueda, Yasumichi Inoue, Hidetoshi Hayashi, Yohei Shimono, Yasumasa Yamada, et al. Monocyte-Derived miRNA-1914-5p Attenuates IL-1β-Induced Monocyte Adhesion and Transmigration. International Journal of Molecular Sciences. 2023. 24. 3. 2829-2829

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Books (1)：

低酸素性虚血性脳症への低体温脳保護療法
月刊「細胞」6月号特集「低酸素生物学の新展開」 2022

Lectures and oral presentations (17)：

miR-1914-5p regulates vascular endothelial cell-monocyte adhesion in the inflammatory environment of atherosclerosis
(2023)
Neuroprotective mechanisms of hypothermia by maintaining astrocytic erythropoietin production
(Neuroscience 2023 2023)
Hypothermia attenuates neurotoxic microglial activation via TRPV4 channel
(2023)
Hypothermic culture enhances secretion of astrocyte-derived neuroprotective erythropoietin
(先端モデル動物支援プラットフォーム若手支援技術講習会 2022)
Hypothermic culture attenuates neuronal apoptosis via prolonged erythropoietin secretion from astrocyte
(第98回日本生理学会大会 2021)

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Education (3)：

2019 - 2022 Nagoya City University
2017 - 2019 Nagoya City University
2013 - 2017 Nagoya City University Medicin Department of Pharmatical and Life Science

Professional career (1)：

博士 (薬学) (名古屋市立大学大学院薬学研究科)

Work history (2)：

2022/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Pathobiology
2021/04 - 2022/03 Japan Society for the Promotion of Science

Awards (3)：

2019/11 - 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019 ベストプレゼンテーション賞
2019/10 - 第13 回次世代を担う若手医療薬科学シンポジウム優秀発表賞
2018/06 - 第64回日本薬学会東海支部大会学生優秀発表賞

Association Membership(s) (6)：

Society for Neuroscience , The Japanese Pharmacological Society , The Pharmaceutical Society of Japan , The Physiological Society of Japan , The Japan Neuroscience Society , The Japanese Society for Neurochemistry

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