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J-GLOBAL ID：202201017040953559 Update date: Mar. 27, 2025

CHEN Kelvin Yigene

Affiliation and department：
Job title： Assistant Professor
Papers (5)：

Kelvin Y. Chen, Tatsuya Kibayashi, Ambre Giguelay, Mayu Hata, Shunsuke Nakajima, Norihisa Mikami, Yusuke Takeshima, Kenji Ichiyama, Ryusuke Omiya, Leif S. Ludwig, et al. Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3. Nature. 2025
Kelvin Y. Chen, Yusuke Takeshima, Andre L. Zorzetto-Fernandes, Katsuhiro Makino, Tatsuya Kibayashi, Mayu Hata, Kenji Ichiyama, Josh Croteau, Kevin Taylor, Shimon Sakaguchi. Joint single-cell measurements of surface proteins, intracellular proteins and gene expression with icCITE-seq. 2025
Eleni P. Mimitou, Caleb A. Lareau, Kelvin Y. Chen, Andre L. Zorzetto-Fernandes, Yuhan Hao, Yusuke Takeshima, Wendy Luo, Tse-Shun Huang, Bertrand Z. Yeung, Efthymia Papalexi, et al. Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells. Nature Biotechnology. 2021. 39. 10. 1246-1258
Ryoji Kawakami, Yohko Kitagawa, Kelvin Y Chen, Masaya Arai, Daiya Ohara, Yamami Nakamura, Keiko Yasuda, Motonao Osaki, Norihisa Mikami, Caleb A Lareau, et al. Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells. Immunity. 2021. 54. 5. 947-961
Norihisa Mikami, Ryoji Kawakami, Kelvin Y. Chen, Atsushi Sugimoto, Naganari Ohkura, Shimon Sakaguchi. Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation. Proceedings of the National Academy of Sciences. 2020. 117. 22. 12258-12268

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