Rchr
J-GLOBAL ID：202201019438275677
Update date: Sep. 24, 2024
Kosakamoto Hina
コサカモト ヒナ | Kosakamoto Hina
Affiliation and department：
Job title：
Postdoctoral researcher
Research field (2)：
Genetics
, Molecular biology
Research keywords (6)：
Metabolism
, Aging
, Physiology
, Drosophila melanogaster
, Amino acid nutrition
, Molecular biology
Research theme for competitive and other funds (3)：
- 2022 - 2025 内在及び人工アミノ酸センサーの同定と開発
- 2022 - 2024 Molecular mechanisms of tyrosine sensing for adaptation to protein scarcity
- 2020 - 2022 組織特異的な新規アミノ酸センシング機構の解明
Papers (17)：
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Hina Kosakamoto, Chisako Sakuma, Rina Okada, Masayuki Miura, Fumiaki Obata. Context-dependent impact of the dietary non-essential amino acid tyrosine on Drosophila physiology and longevity. Science Advances. 2024. 10. 35
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Yuka Fujita, Hina Kosakamoto, Fumiaki Obata. Microbiota-derived acetylcholine can promote gut motility in Drosophila melanogaster. Philosophical Transactions of the Royal Society B: Biological Sciences. 2024
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Hina Kosakamoto, Masayuki Miura, Fumiaki Obata. Epidermal tyrosine catabolism is crucial for metabolic homeostasis and survival against high-protein diets in Drosophila. Development. 2024. 151. 1
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Hina Kosakamoto, Fumiaki Obata, Junpei Kuraishi, Hide Aikawa, Rina Okada, Joshua N. Johnstone, Taro Onuma, Matthew D. W. Piper, Masayuki Miura. Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila. Nature Communications. 2023. 14. 1
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Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, et al. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. PLOS Genetics. 2023. 19. 6. e1010761-e1010761
ｍore...
Books (2)：
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月刊誌『科学』モデル動物で解明する寿命とアミノ酸摂取の関係
岩波書店 2024
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実験医学2020年12月号 腸内細菌が増悪するネクローシス性全身炎症
羊土社 2020 ISBN:9784758125383
Lectures and oral presentations (21)：
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Early-life amino acid sensing for lifespan regulation in Drosophila
(Dietology Symposium 2024)
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The essential function of a nonessential amino acid as an indicator of protein satiety
(International Day of Women and Girls in Science Symposium 2024)
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Regulatory mechanisms of nutritional signaling by sensing non-essential amino acid tyrosine
(2023)
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Non-essential amino acid tyrosine regulates organismal lifespan and feeding behaviour
(Asia Pacific Drosophila Research Conference 6 2023)
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Tyrosine sensing regulates adaptation to changing protein environments in Drosophila
(Mechanisms of Metabolic Signaling meeting 2023)
ｍore...
Education (3)：
- 2019 - 2022 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2017 - 2019 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2013 - 2017 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
Professional career (1)：
- Doctor of Pharmaceutical Sciences (The University of Tokyo)
Work history (1)：
- 2022/04 - 現在 RIKEN Center for Biosystems Dynamics Research Special Postdoctoral Researcher
Awards (3)：
- 2023/03 - RIKEN BAIHO Award
- 2022/09 - Daigoro Moriwaki Award Grand Prize Sensing of the non-essential amino acid tyrosine governs the response to dietary protein intake in Drosophila
- 2022/06 - Japanese Society of Developmental Biologists Best poster award
Association Membership(s) (2)：
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