Rchr
J-GLOBAL ID:202301010250577706   Update date: Apr. 17, 2024

SAWAKI Daigo

サワキ ダイゴ | SAWAKI Daigo
Affiliation and department:
Research theme for competitive and other funds  (7):
  • 2022 - 2025 NADHを標的とした新たな心臓線維化治療法の開発
  • 2021 - 2024 多次元質量分析による大動脈疾患のメタボロームバイオマーカー解析
  • 2021 - 2024 心筋マクロファージの細胞老化に着目したHFpEF病態解明と治療法開発
  • 2021 - 2023 プロテオスタシス破綻に基づく心アミロイドーシスの理解と革新的診断法開発
  • 2020 - 2023 平滑筋ミオシン変異による家族性大動脈解離の分子機構解明と治療法開発
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Papers (45):
  • Shota Tomida, Tamaki Ishima, Daigo Sawaki, Yasushi Imai, Ryozo Nagai, Kenichi Aizawa. Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection. International journal of molecular sciences. 2023. 24. 20
  • Daigo Sawaki, Yanyan Zhang, Amel Mohamadi, Maria Pini, Zaineb Mezdari, Larissa Lipskaia, Suzain Naushad, Lucille Lamendour, Dogus Murat Altintas, Marielle Breau, et al. Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction. JCI insight. 2023. 8. 8
  • Gabor Czibik, Zaineb Mezdari, Dogus Murat Altintas, Juliette Bréhat, Maria Pini, Thomas d'Humières, Thaïs Delmont, Costin Radu, Marielle Breau, Hao Liang, et al. Dysregulated Phenylalanine Catabolism Plays a Key Role in the Trajectory of Cardiac Aging. Circulation. 2021. 144. 7. 559-574
  • Maria Pini, Gabor Czibik, Daigo Sawaki, Zaineb Mezdari, Laura Braud, Thaïs Delmont, Raquel Mercedes, Cécile Martel, Nelly Buron, Geneviève Marcelin, et al. Adipose tissue senescence is mediated by increased ATP content after a short-term high-fat diet exposure. Aging cell. 2021. 20. 8. e13421
  • Nathalie Mougenot, Delphine Mika, Gabor Czibik, Elizabeth Marcos, Shariq Abid, Amal Houssaini, Benjamin Vallin, Aziz Guellich, Hind Mehel, Daigo Sawaki, et al. Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction. Cardiovascular research. 2019. 115. 12. 1778-1790
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MISC (11):
  • Bo K. Son, Toru Suzuki, Daigo Sawaki, Kenichi Aizawa, Hong Zhan, Junichi Ishida, Takayoshi Matsumura, Ryozo Nagai. KLF6 Modulates Aortic Aneurysm Formation by Balancing Between Inflammatory and TGF beta Signaling Pathways. CIRCULATION. 2012. 126. 21
  • Junichi Ishida, Toru Suzuki, Kenichi Aizawa, Daigo Sawaki, Takayoshi Matsumura, Scott L. Friedman, Ryozo Nagai. Kruppel-like Factor 6 Promotes Obesity and Glucose Intolerance Through Adipocyte Differentiation. CIRCULATION. 2012. 126. 21
  • Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott Friedman, Ryozo Nagai. Cardiomyocyte Regulates Cardiac Fibrosis through Cell to Cell Interaction Mediated by KLF6. CIRCULATION. 2012. 126. 21
  • Kenichi Aizawa, Toru Suzuki, Hong Zhan, Daigo Sawaki, Junichi Ishida, Takayoshi Mastumura, Ryozo Nagai. Klf5 Mediates a New Regulatory Pathway of Pathologic Vascular Injury Through DNA Double-Strand Break/Repair System. CIRCULATION. 2011. 124. 21
  • Daigo Sawaki, Toru Suzuki, Kenichi Aizawa, Takayoshi Matsumura, Yoshiko Munemasa, Junichi Ishida, Scott L. Fridman, Ryozo Nagai. KLF6 Modulates Recruitment and Polarization of Inflammatory Cells Through Cardiomyocytes in Initiation of Cardiac Fibrosis. CIRCULATION. 2011. 124. 21
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