2020 - 2023 Fundamental research of antitumor activity of arsenic compound in combination with active bufadienolide compounds against glioblastoma cells
2016 - 2019 Protective mechanism of FAD012, a ferulic acid derivative, against ischemic brain injury.
2013 - 2016 Preventive effects of novel ferulic acid derivatives on cerebral ischemia-induced swallowing dysfunction
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Papers (24)：
Yu-Chen Jiang, Jia-Yi Dou, Mei-Yan Xuan, Chong Gao, Zhao-Xu Li, Li-Hua Lian, Zhen-Yu Cui, Ji-Xing Nan, Yan-Ling Wu. Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling. journal of agricultural and food chemistry. 2024. 2024. 72. 15740-15754
Jia-yi Dou, Zhen-yu Cui, Mei-yan Xuan, Chong Gao, Zhao-Xu Li, Li-hua Lian, Hao-zhen Cui, Ji-xing Nan, Yan-ling Wu. Diallyl disulfide, the bioactive component of Allium species, ameliorates pulmonary fibrosis by mediating the crosstalk of farnesoid X receptor and yes-associated protein 1 signaling pathway. Phytother Res. 2024. 1-13
Jiayi Dou, Haozhen Cui, Zhenyu Cui, Meiyan Xuan, Chong Gao, Zhaoxu Li, Lihua Lian, Jixing Nan, Yanling Wu. Pterostilbene exerts cytotoxicity on activated hepatic stellate cells by inhibiting excessive proliferation through the crosstalk of Sirt1 and STAT3 pathways. 2023. 1-18
YuChen Jiang, LiShuang Hou, JiaYi Dou, Meiyan Xuan, ZhenYu Cui, LiHua Lian, JiXing Nan, YanLing Wu. Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage. Phytomedicine. 2023
Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, et al. Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. Int. J. Mol. Sci. 2023. 11. 24. 1-18
