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J-GLOBAL ID:202301012539091960   Update date: Mar. 09, 2025

Sanda Takaomi

サンダ タカオミ | Sanda Takaomi
Affiliation and department:
Job title: Associate Professor
Research field  (4): Hematology and oncology ,  Tumor biology ,  Molecular biology ,  Genomics
Research keywords  (7): Transcription factor ,  Enhancer ,  Oncogene ,  T-cell acute lymphoblastic leukemia ,  Adult T-cell leukemia ,  Neuroblastoma ,  Zebrafish
Papers (96):
  • Haruhito Totani, Takayoshi Matsumura, Rui Yokomori, Terumasa Umemoto, Yuji Takihara, Chong Yang, Lee Hui Chua, Atsushi Watanabe, Takaomi Sanda, Toshio Suda. Mitochondria-enriched hematopoietic stem cells exhibit elevated self-renewal capabilities, thriving within the context of aged bone marrow. Nature aging. 2025
  • Xiaoman Shao, Rui Yokomori, Jolynn Zu Lin Ong, Haoqing Shen, Dennis Kappei, Leilei Chen, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda. Transcriptional regulatory program controlled by MYB in T-cell acute lymphoblastic leukemia. Leukemia. 2024
  • Hyoju Kim, Tze King Tan, Dean Zi Yang Lee, Xiao Zi Huang, Jolynn Zu Lin Ong, Michelle A. Kelliher, Allen Eng Juh Yeoh, Takaomi Sanda, Shi Hao Tan. Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia. Leukemia. 2024
  • Atsushi Watanabe, Lu Wang, Tze King Tan, Kevin Y Urayama, Toshihiko Kizuki, Chiaki Komatsu, Keiko Kagami, Tamao Shinohara, Shin Kasai, Minori Tamai, et al. Acquired copy number amplification at the MYC enhancer in human B-precursor acute lymphoblastic leukemia cell lines. Cancer science. 2024
  • Chong Yang, Rui Yokomori, Lee Hui Chua, Shi Hao Tan, Mun Yee Koh, Haruhito Totani, Takaomi Sanda, Toshio Suda. Deciphering the regulatory landscape of murine splenic response to anemic stress at single-cell resolution. Blood Advances. 2024. 8. 7. 1651-1666
more...
MISC (7):
  • Koshi Akahane, Zhaodong Li, Julia Etchin, Alla Berezovskaya, Evisa Gjini, Craig E. Masse, Wenyan Miao, Jennifer Rocnik, Rosana Kapeller, Jeremy R. Greenwood, et al. Anti-Leukemic Activity of the TYK2 Selective Inhibitor Ndi-031301 in T-Cell Acute Lymphoblastic Leukemia. BLOOD. 2016. 128. 22
  • Regina Wan Ju Wong, Phuong Thi Ngoc Cao, Wei Zhong Leong, Alice Wei Yee Yam, Tinghu Zhang, Shinsuke Iida, Takashi Okamoto, Ryuzo Ueda, Nathanael S. Grey, Takashi Ishida, et al. Identification of Super-Enhancer-Associated Cancer Genes Provides Novel Therapeutic Targets in Adult T-Cell Leukemia/Lymphoma. BLOOD. 2016. 128. 22
  • 三田 貴臣, Liau Wei-Siang, Mansour Marc R., Kwiatkowski Nicholas, Zhang Tinghu, Lawton Lee N., Tan Shi Hao, Wang Chelsia Q., 大里 元美, Gray Nathanael S., et al. 造血器腫瘍における分子病態の理解と臨床応用への展望 T細胞性急性リンパ性白血病におけるコア転写調節回路とオンコジェニックエンハンサーの解明. 日本癌学会総会記事. 2015. 74回. SST5-2
  • Koshi Akahane, Takaomi Sanda, Marc R. Mansour, Julia Etchin, Ng Cherry, David M. Weinstock, Anthony Letai, Daniel J. DeAngelo, A. Thomas Look. HSP90 Inhibition Has Potent Activity Against T-Cell Acute Lymphoblastic Leukemia (T-ALL) Through Degradation Of TYK2 Kinase. BLOOD. 2013. 122. 21
  • Takaomi Sanda, Ryuzo Ueda. Aberrant signal transductions in leukemia cell. Nippon rinsho. Japanese journal of clinical medicine. 2007. 65. 118-123
more...
Education (2):
  • 2002 - 2006 Nagoya City University Graduate School of Medical Sciences
  • 1994 - 2000 Nagoya City University Medical School
Professional career (2):
  • PhD (Nagoya City University)
  • MD (Nagoya City University)
Work history (8):
  • 2023/09 - 現在 Nagoya City University Graduate School of Medical Sciences Department of Hematology & Oncology Associate Professor
  • 2020/01 - 2023/08 National University of Singapore Department of Medicine Associate Professor
  • 2013/07 - 2023/08 National University of Singapore Cancer Science Institute of Singapore Principal Investigator
  • 2013/07 - 2019/12 National University of Singapore Department of Medicine Assistant Professor
  • 2010/01 - 2013/03 Harvard Medical School Dana-Farber Cancer Institute Instructor
Show all
Committee career (1):
  • 2022 - 現在 Japanese Society of Hematology Councilor
Awards (3):
  • 2013 - National Research Foundation, Singapore NRF Fellowship
  • 2011 - National Cancer Institute/National Cancer Institute, US K99 Award
  • 2009 - Japanese Society for the Promotion of Science Postdoctoral Fellowship for Research Abroad
Association Membership(s) (5):
American Society of Hematology ,  American Association for Cancer Research ,  Japanese Cancer Association ,  Japanese Society of Hematology ,  Japanese Society of Internal Medicine
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