Rchr
J-GLOBAL ID：202301015528900092
Update date: Oct. 15, 2024
Kubota Hisayoshi
クボタ ヒサヨシ | Kubota Hisayoshi
Affiliation and department：
Job title：
Assistant professor
Homepage URL (1)：
https://www.fujita-hu.ac.jp/icbs/behav-neuropharmacol/
Research field (1)：
Psychiatry
Research keywords (10)：
Behavioral Pharmacology
, Psychiatric Disease
, Neurodegenerative Disease
, Drug Dependence
, Schizophrenia
, Bipolar disorder
, Parkinson's disease
, Alzheimer's disease
, Decision-making
, Empathy
Research theme for competitive and other funds (3)：
- 2024 - 2027 パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発
- 2024 - 2026 包括的フォワード・ケモジェネティクス法による共感性の神経メカニズムの解明
- 2024 - 2025 向社会的行動を司る共感性の神経基盤の探索
Papers (11)：
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Hitomi Kurahashi, Kazuo Kunisawa, Kenji F. Tanaka, Hisayoshi Kubota, Masaya Hasegawa, Mai Miyachi, Yuka Moriya, Yoichi Hasegawa, Taku Nagai, Kuniaki Saito, et al. Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid. Neuropsychopharmacology. 2024
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Hisayoshi Kubota, Kazuo Kunisawa, Masaya Hasegawa, Hitomi Kurahashi, Kazuhiro Kagotani, Yuki Fujimoto, Akihito Hayashi, Ryoji Sono, Takehiko Tsuji, Kuniaki Saito, et al. Soy lysolecithin prevents hypertension and cognitive impairment induced in mice by high salt intake by inhibiting intestinal inflammation. Neurochemistry international. 2024. 180. 105858-105858
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Hisayoshi Kubota, Xinzhu Zhou, Xinjian Zhang, Hirohisa Watanabe, Taku Nagai. Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson’s Disease. International Journal of Molecular Sciences. 2024. 25. 16. 8849-8849
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Hisayoshi Kubota, Kazuo Kunisawa, Bolati Wulaer, Masaya Hasegawa, Hitomi Kurahashi, Takatoshi Sakata, Hiroyuki Tezuka, Masanori Kugita, Shizuko Nagao, Taku Nagai, et al. High salt induces cognitive impairment via the interaction of angiotensin II-AT1 and prostaglandin E2-EP1 systems. British Journal of Pharmacology. 2023
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Hisayoshi Kubota, Kazuo Kunisawa, Moe Niijima, Mami Hirakawa, Yuko Mori, Masaya Hasegawa, Suwako Fujigaki, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, et al. Deficiency of kynurenine 3-monooxygenase exacerbates impairment of prepulse inhibition induced by phencyclidine. Biochemical and Biophysical Research Communications. 2022. 629. 142-151
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MISC (13)：
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田辺萌夏, 田辺萌夏, 國澤和生, 齋藤いまり, 小菅愛加, 河合智貴, 窪田悠力, 齋藤邦明, 齋藤邦明, 齋藤邦明, et al. Social isolation in childhood induces abnormalities of gut microbiota composition and spatial cognitive impairment. 腸内細菌学雑誌. 2023. 37. 2
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國澤和生, 田辺萌夏, 齋藤いまり, 小菅愛加, 河合智貴, 窪田悠力, 齋藤邦明, 齋藤邦明, 鍋島俊隆, 鍋島俊隆, et al. レパミピドは大腸杯細胞の増殖を促し,社会的隔離ストレスによる行動異常を緩解する. 日本生理学雑誌(Web). 2023. 85. 3
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長谷川眞也, 毛利彰宏, 毛利彰宏, 國澤和生, 窪田悠力, 倉橋仁美, 小菅愛加, 山本康子, 齋藤邦明, 齋藤邦明, et al. ミクログリア由来キヌレニン-3-モノオキシゲナーゼの発現低下に関連したキヌレン酸の増加は慢性予測不能軽度ストレスによるうつ様行動およびHPA系の調節不全に関与する. 日本神経化学会大会抄録集(Web). 2022. 65th
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山岸周平, 毛利彰宏, 毛利彰宏, 國澤和生, 小菅愛加, 窪田悠力, 倉橋仁美, 長谷川眞也, 山本康子, 齋藤邦明, et al. Disruption of the blood-placental barrier by maternal immune activation via indoleamine-2,3 dioxygenase-1 is involved in neurodevelopmental impairments of offsprings. 日本生物学的精神医学会(Web). 2022. 44th
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田辺萌夏, 國澤和生, 齋藤いまり, 小菅愛加, 河合智貴, 窪田悠力, 齋藤邦明, 齋藤邦明, 齋藤邦明, 鍋島俊隆, et al. Decrease of goblet cells in the colon induce spatial cognitive dysfunction followed by social isolation in childhood. 日本生物学的精神医学会(Web). 2022. 44th
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Patents (1)：
Education (3)：
- 2020 - 2023 Fujita Health University Doctoral Course, Graduate School of Health Science
- 2018 - 2020 Fujita Health University Master's Course, Graduate School of Health Science
- 2014 - 2018 Fujita Health University School of Medical Sciences Medical Technology
Professional career (2)：
- M.S. (Fujita Health University)
- Ph.D. (Fujita Health University)
Work history (1)：
- 2022/04 - 現在 Fujita Health University Division of Behavioral Neuropharmacology, International Center for Brain Science (ICBS) Assistant professor
Awards (2)：
- 2021/03 - CINP 2021 Student Encouragement Award
- 2019/03 - 第 28 回神経行動薬理若手研究者の集い 優秀発表賞
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