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J-GLOBAL ID:202301015568320544   Update date: Feb. 19, 2025

Arimura Sumimasa

アリムラ スミマサ | Arimura Sumimasa
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Affiliation and department:
Job title: Instrcutor
Research field  (1): Molecular biology
Research keywords  (1): 「機能的細胞の創製とその応用」
Research theme for competitive and other funds  (9):
  • 2025 - 2029 Lead Optimization, Target Engagement and Efficacy Studies of Locally Bioavailable COX-2 Inhibitors for Preventing Colon Cancer Progression in FAP Children
  • 2023 - 2028 Regulation of atrophy-induced progenitor cells in the gastric corpus
  • 2021 - 2022 Therapeutic Small Intestinal Cell Replacement in Mouse Models
  • 2018 - 2020 Molecular mechanisms underlying microenvironment-regulated tumor malignant progression
  • 2018 - 2019 Small Intestinal Organoid Engraftment
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Papers (13):
  • Sumimasa Arimura, Sarah To, Jason C. Mills. Changing Fate: How EGFRs "Pit" Cell Versus Cell in the Stomach. Gastroenterology. 2024. 167. 3. 441-442
  • Mahliyah Adkins-Threats#, Sumimasa Arimura#, Yang-Zhe Huang, Margarita Divenko, Sarah To, Heather Mao, Yongji Zeng, Jenie Y. Hwang, Joseph R. Burclaff, Shilpa Jain, et al. Metabolic regulator ERRγ governs stem cell differentiation into acid-secreting parietal cells. Cell Stem Cell. 2024. 31. 6. 886-903
  • Li Yang, Xiaomin Chen, Christy Lee, Jiejun Shi, Emily B. Lawrence, Lanjing Zhang, Yumei Li, Nan Gao, Sung Yun Jung, Chad J Creighton, et al. Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. Journal of Experimental & Clinical Cancer Research. 2023. 42. 1. 113-129
  • Sumimasa Arimura, Akane Inoue-Yamauchi, Kotoe Katayama, Tatsuo Kanno, Hiroki Jozawa, Seiya Imoto, Yuji Yamanashi. Loss of Dok-3 in non-tumor cells induces malignant transformation of benign epithelial tumor cells of the intestine. Cancer Research Communications. 2022. 2. 12. 1590-1600
  • Zachary K Criss II, Nobel Bhasin, Sara C Di Rienzi, Anubama Rajan, Kali Deans-Fielder, Ganesh Swaminathan, Nabiollah Kamyabi, Xi-Lei Zeng, Harsha Doddapaneni, Vipin K Menon, et al. Drivers of transcriptional variance in human intestinal epithelial organoids. Physiological Genomics. 2021. 53. 11. 486-508
more...
Books (3):
  • Establishment of a new therapeutic concept for NMJ-related disorders
    Jikken- Igaku 33: 603-606 2015
  • Development of a new therapeutic concept for neuromuscular diseases with NMJ dysfunction
    Igaku-no-AyumiIgaku 255: 1195-1196 2015
  • DOK7 gene therapy benefits mouse models of diseases characterized by defects in the neuromuscular junction
    Life Science-Shinchaku-Ronbun Reviews: e-book 2014
Lectures and oral presentations  (11):
  • 招待講演1: Stem Cell Differentiation in Gastrointestinal Organoids
    (Texas Medical Center Digestive Disease Center Research Forum 2025)
  • Regulatory Mechanisms that Make Gastric Stem Cells Stem Cells
    (2024)
  • Metabolic Influence On Gastric Stem Cell Differentiation
    (The 12th Metabolism in Cancer Symposium at MD Anderson Cancer Center 2023)
  • 招待講演4: Small Intestinal Organoids Engraftment
    (The Stem Cells and Regenerative Medicine Center Meeting 2019 2019)
  • Establishment of a new therapeutic concept for NMJ-related disorders
    (The 5th Japanese Researchers Association of Science and Technology 2019)
more...
Professional career (2):
  • 医学博士 (京都大学大学院 医学研究科)
  • 薬剤師
Work history (5):
  • 2019 - 現在 ベイラー医科大学 専任講師
  • 2018 - 2019 ヒューストン大学 博士研究員
  • 2013 - 2018 The University of Tokyo The Institute of Medical Science
  • 2009 - 2013 The University of Tokyo The Institute of Medical Science
  • 2008 - 2009 京都大学大学院 医学研究科 グローバルCOE研究員
Committee career (1):
  • 2019 - 現在 米国NPO法人Japanese Researchers Association of Science and Technology in Texas (JRAST) / サイエンスを遊ぼうの会 常任理事
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