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J-GLOBAL ID:202401008692272435   Update date: Oct. 08, 2024

Uchinomiya Shohei

ウチノミヤ ショウヘイ | Uchinomiya Shohei
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Affiliation and department:
Job title: assistant professor
Research field  (2): Pharmaceuticals - analytical and physicochemistry ,  Chemical biology
Research keywords  (3): 代謝経路 ,  蛍光イメージング ,  ケミカルバイオロジー
Research theme for competitive and other funds  (4):
  • 2021 - 2024 様々な代謝経路活性の一細胞検出を可能とする新規蛍光イメージング戦略の開発
  • 2019 - 2021 Development of a chemical probe for single-cell imaging of FAO pathway and the mechanism of alternation of FAO activity
  • 2017 - 2019 Evaluation of activity of fatty acid beta oxidation in live cells with a fluorescent probe and its application to drug discovery
  • 2010 - 2012 Hisタグ/Ni(II)-NTAペアによる細胞発現タンパク質のラベル化技術の開発
Papers (23):
  • Junhao Li, Kengo Hamamura, Yuya Yoshida, Shimpei Kawano, Shohei Uchinomiya, Jiahongyi Xie, Damiana Scuteri, Kohei Fukuoka, Orion Zaitsu, Fumiaki Tsurusaki, et al. Hericenone C attenuates the second phase of formalin-induced nociceptive behavior by suppressing the accumulation of CD11c-positive cells in the paw epidermis via phosphorylated P65. Biochemical and biophysical research communications. 2024. 720. 150077-150077
  • Yusuke Katsuma, Isao Matsui, Ayumi Matsumoto, Hiroki Okushima, Atsuhiro Imai, Yusuke Sakaguchi, Takeshi Yamamoto, Masayuki Mizui, Shohei Uchinomiya, Hisakazu Kato, et al. Endogenous activation of peroxisome proliferator-activated receptor-α in proximal tubule cells in counteracting phosphate toxicity. American journal of physiology. Renal physiology. 2024. 327. 2. F208-F223
  • Daisuke Sato, Yuya Matsuo, Yuki Nishime, Shohei Uchinomiya, Akio Ojida. In situ detection of enzymatic activities by the bioorthogonal reaction-coupled assay using a dialkoxysilylated fluorogenic probe. Chemistry Letters. 2024. 53. 3
  • Manami Tomomatsu, Naoto Imamura, Hoshimi Izumi, Masatsugu Watanabe, Masataka Ikeda, Tomomi Ide, Shohei Uchinomiya, Akio Ojida, Mirinthorn Jutanom, Kazushi Morimoto, et al. Oxidized-LDL Induces Metabolic Dysfunction in Retinal Pigment Epithelial Cells. Biological & pharmaceutical bulletin. 2024. 47. 3. 641-651
  • Ayumi Matsumoto, Isao Matsui, Shohei Uchinomiya, Yusuke Katsuma, Seiichi Yasuda, Hiroki Okushima, Atsuhiro Imai, Takeshi Yamamoto, Akio Ojida, Kazunori Inoue, et al. Spatiotemporally quantitative in vivo imaging of mitochondrial fatty acid β-oxidation at cellular-level resolution in mice. American journal of physiology. Endocrinology and metabolism. 2023. 325. 5. E552-E561
more...
MISC (3):
  • 内之宮 祥平. ケミカルバイオロジー的観点からの代謝経路の開拓. あいみっく. 2021. 42. 3. 72-75
  • 内之宮祥平, 王子田彰夫. 蛍光小分子プローブによる代謝経路活性の生細胞イメージング. 化学工業. 2019. 5. 248-255
  • 内之宮祥平, 浜地格. タンパク質の人工機能化の基礎とセンサーへの応用. ぶんせき. 2010. 432. 653-660
Lectures and oral presentations  (1):
  • 有機小分子プローブによるミトコンドリア/ペルオキシソーム脂肪酸β酸化の蛍光検出
    (第66回 日本脂質生化学会 2024)
Work history (1):
  • 2015/09 - 現在 Kyushu University Graduate School of Pharmaceutical Sciences assistant professor
Awards (1):
  • 2024/09 - 第17回バイオ関連化学シンポジウム講演賞
Association Membership(s) (4):
生化学会 ,  日本ケミカルバイオロジー学会 ,  日本薬学会 ,  日本化学会
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