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J-GLOBAL ID：202401011025624979   Update date: Feb. 20, 2025

Nomura Masashi

ノムラ マサシ | Nomura Masashi
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Affiliation and department：
The University of Tokyo Faculty of Medicine University Hospital Department of Neurosurgery

About The University of Tokyo Faculty of Medicine University Hospital Department of Neurosurgery


Job title： Assistant professor
Research field  (3)： Systems genomics ,  Neurosurgery ,  Tumor biology
Research keywords  (3)： シングルセルゲノミクス ,  マルチオミクス解析 ,  グリーオーマ
Research theme for competitive and other funds  (2)：
  • 2024 - 2026 ナノポアシークエンスを用いたIDH変異神経膠腫に対する術中悪性度診断システムの開発
  • 2018 - 2020 Elucidating mechanisms of lower grade glioma recurrences using next generation sequencing
Papers (28)：
  • Taijun Hana, Akitake Mukasa, Masashi Nomura, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka, et al. AB019. Detailed analysis of DNA hydroxymethylation observed with the malignant progression of IDH-mutant gliomas. Chinese clinical oncology. 2024. 13. Suppl 1. AB019
  • Avishay Spitzer, Simon Gritsch, Masashi Nomura, Alexander Jucht, Jerome Fortin, Ramya Raviram, Hannah R Weisman, L Nicolas Gonzalez Castro, Nicholas Druck, Rony Chanoch-Myers, et al. Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma. Cancer cell. 2024. 42. 5. 904-914
  • Alissa C Greenwald, Noam Galili Darnell, Rouven Hoefflin, Dor Simkin, Christopher W Mount, L Nicolas Gonzalez Castro, Yotam Harnik, Sydney Dumont, Dana Hirsch, Masashi Nomura, et al. Integrative spatial analysis reveals a multi-layered organization of glioblastoma. Cell. 2024. 187. 10. 2485-2501
  • Taijun Hana, Akitake Mukasa, Masashi Nomura, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka, et al. Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas. Cancer science. 2024. 115. 5. 1706-1717
  • Takeshi Maemura, Atsuto Katano, Hirokazu Takami, Masashi Nomura, Shunsaku Takayanagi, Hideomi Yamashita. Central Neurocytoma Treated Using Supratentorial Ventricle Radiotherapy: A Single-Institution Analysis of Five Cases in Adjuvant or Salvage Settings After Surgery. Cureus. 2024. 16. 3. e56132
ｍore...
MISC (1)：
  • Shota Tanaka, Akitake Mukasa, Shunsaku Takayanagi, Shunsuke Yanagisawa, Masashi Nomura, Nobuhito Saito. GENETICALLY-GUIDED TREATMENTS OF GLIOBLASTOMA IN THE ELDERLY POPULATION. NEURO-ONCOLOGY. 2016. 18. 108-108
Lectures and oral presentations  (6)：
  • Multi-layered transcriptional architecture of glioblastoma ecosystems revealed by large scale-single nucleus RNA sequencing
    (第42回 札幌国際がんシンポジウム 2024)
  • 大規模シングルセルシークエンシングにより明らかとなった 膠芽腫エコシステムの新分類
    (第42回 日本脳腫瘍病理学会 2024)
  • Opposing Dysregulation of a Common Set of Genes in H3-G34R and H3-K27M Gliomas Associated with PRC2 Activity and Stalled Differentiation
    (23rd The International Conference on Brain Tumor Research and Therapy 2023)
  • Dissecting GBM evolution following standard-of-care by large-scale longitudinal single nucleus RNA-sequencing
    (28th Annual Meeting of the Society for Neuro-Oncolo 2023)
  • Longitudinal single cell genomic analysis of glioblastoma
    (4th Harvard-Heidelberg Science of Neuro-Oncology Symposium 2022)
ｍore...
Education (2)：
  • 2014 - 2018 The University of Tokyo Faculty of Medicine
  • 2000 - 2006 Kyoto Prefectural University of Medicine
Work history (13)：
  • 2024/01 - 現在 東京大学医学部附属病院 脳神経外科 助教
  • 2019/01 - 2023/12 ハーバード医科大学 マサチューセッツ総合病院 ・ブロード研究所 分子病理 リサーチフェロー
  • 2020/01 - 2022/06 日本学術振興会 海外特別研究員
  • 2018/04 - 2018/12 東京大学医学部附属病院 脳神経外科 特任助教
  • 2014/10 - 2018/03 東京大学医学部 東京大学先端科学技術研究センター ゲノムサイエンス分野 博士課程大学院生
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Association Membership(s) (6)：
Society for Neuro-Oncology ,  分子脳神経外科学会 ,  日本脳腫瘍病理学会 ,  日本癌学会 ,  日本脳腫瘍学会 ,  日本脳神経外科学会
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