Research field (2):
Pharmaceuticals - chemistry and drug development
, Bioorganic chemistry
Research theme for competitive and other funds (4):
2024 - 2027 人工触媒による化学修飾を用いた転写因子活性化
2023 - 2025 個体内人工触媒反応による革新的抗がん戦略の創出
2023 - 2025 Development of chemical catalyst systems toward a novel therapeutic strategy
2024 - 2025 化学触媒を用いたヒストンアセチル化によるがん治療戦略の開発
Papers (5):
Yuki Yamanashi, Shinpei Takamaru, Atsushi Okabe, Satoshi Kaito, Yuto Azumaya, Yugo R. Kamimura, Kenzo Yamatsugu, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, et al. Chemical catalyst manipulating cancer epigenome and transcription. Nature Communications. 2025. 16. 1
Menghan Xu, Yuki Yamanashi, Motomu Kanai. Spectral control of photoenzyme through allosteric chromophore tuning. Chem. 2025. 102430-102430
Hiroki Umeda, Kayo Suda, Daisuke Yokogawa, Yuto Azumaya, Nobuo Kitada, Shojiro A Maki, Shigehiro A Kawashima, Harunobu Mitsunuma, Yuki Yamanashi, Motomu Kanai. Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids. Angewandte Chemie (International ed. in English). 2024. e202405605
Yuki Yamanashi, Motomu Kanai. Chemical Catalyst-Promoted Regioselective Histone Acylation. Supramolecular Catalysis: New Directions and Developments. 2021. 537-546
Yusuke Fujiwara, Yuki Yamanashi, Akiko Fujimura, Yuko Sato, Tomoya Kujirai, Hitoshi Kurumizaka, Hiroshi Kimura, Kenzo Yamatsugu, Shigehiro A Kawashima, Motomu Kanai. Live-cell epigenome manipulation by synthetic histone acetylation catalyst system. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 4
Education (3):
- 2023 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2022 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2020 The University of Tokyo Faculty of Pharmaceutical Sciences
Work history (3):
2024/02 - 現在 The University of Tokyo Graduate School of Pharmaceutical Sciences Assistant Professor
2023/04 - 2024/01 The University of Tokyo Graduate School of Pharmaceutical Sciences Project Assistant Professor
2022/04 - 2023/03 日本学術振興会特別研究員(DC1)
Awards (2):
2023 - 日本薬学会 第143年会 学生優秀発表賞
2021 - 第53回 若手ペプチド夏の勉強会 ポスター発表優秀賞
Association Membership(s) (3):
Japanese Society for Chemical Biology
, The Chemical Society of Japan
, The Pharmaceutical Society of Japan