Research field (7):
Hematology and oncology
, Pharmacology
, Physiology
, Gastroenterology
, Tumor biology
, Molecular biology
, Pharmaceuticals - health and biochemistry
2022 - 2024 Development of antitumor drug for pediatric cancer by utilizing probiotic derived antitumor molecules
2019 - 2023 The development of novel pancreatic cancer therapeutics based on probiotic-derived anti-tumor molecules.
2018 - 2022 Identifications and functional analyses of beneficial bacteria-derived bioactive molecules
2016 - 2018 Identification of probiotic derived bioactive molecule and clarification of its recognition system and activation mechanisms of cell signaling
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Papers (38):
Yuya Sugiyama, Hiroaki Konishi, Tatsuya Dokoshi, Hiroki Tanaka, Yu Kobayashi, Takahiro Sasaki, Koji Yamamoto, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, et al. hsa_circ_0015388 Reduces Macrophage Derived Reactive Oxygen Species in Crohn's Disease. Inflammatory bowel diseases. 2025
Alex Q Lee, Hiroaki Konishi, Masami Ijiri, Yueju Li, Arun Panigrahi, Jeremy Chien, Noriko Satake. Therapeutic efficacy of RAS inhibitor trametinib using a juvenile myelomonocytic leukemia patient-derived xenograft model. Pediatric hematology and oncology. 2024. 41. 5. 367-375
Keita Kojima, Hiroaki Konishi, Kyoka Momosaki, Yuya Komatani, Akira Katsuyama, Koji Nakagawa, Kayoko Kanamitsu, Fumika Yakushiji, Mikihiro Fujiya, Satoshi Ichikawa. Synthesis and biological evaluation of echinomycin analogues as potential colon cancer agent. Scientific reports. 2024. 14. 1. 7628-7628
Takehito Kunogi, Hiroaki Konishi, Aki Sakatani, Kentaro Moriichi, Chikage Yamamura, Koji Yamamoto, Shin Kashima, Katsuyoshi Ando, Nobuhiro Ueno, Hiroki Tanaka, et al. Probiotic-derived ferrichrome induces DDIT3-mediated antitumor effects in esophageal cancer cells. Heliyon. 2024. 10. 6. e28070
Alex Q Lee, Hiroaki Konishi, Elizabeth Helmke, Masami Ijiri, Jan Michael A Lerot, Emma Hicks, Jeremy R Chien, Fredric A Gorin, Noriko Satake. Cmpd10357 to treat B-cell acute lymphoblastic leukemia. Experimental hematology. 2023. 119-120. 8-13
2012 - 2016 Asahikawa Medical University Graduate School of Medicine Doctoral Program in Medicine
2008 - 2010 Kyushu University Graduate School of Medical Sciences Master's Program in Medical Sciences
2004 - 2008 Hiroshima International University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
Work history (6):
2024/04 - 現在 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Lecturer
2023/08 - 2024/03 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Assistant Professor
2022/08 - 2023/07 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Visiting Assistant Professor
2022/08 - 2023/07 University of California, Davis Department of Pediatrics Visiting Research Scholar
2018/05 - 2022/07 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Assistant Professor
2016/04 - 2018/04 Asahikawa Medical University Division of Gastroenterology and Hematology/Oncology, Department of Medicine Visiting Assistant Professor
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Awards (1):
2014/05 - AGA Digestive Disease Week 2014 Poster of Distinction
Association Membership(s) (5):
The Japanese Pharmacological Society
, The Japanese Cancer Association
, The Pharmaceutical Society of Japan
, Japan Society of Clinical Oncology
, The Japanese Society for Mucosal Immunology