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J-GLOBAL ID：202401018691826165
Update date: Apr. 17, 2025 Konishi Hiroaki
コニシ ヒロアキ | Konishi Hiroaki
Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences
About Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences
Job title： Lecturer
Research field (7)：
Hematology and oncology
, Pharmacology
, Physiology
, Gastroenterology
, Tumor biology
, Molecular biology
, Pharmaceuticals - health and biochemistry
Research keywords (7)：
Pediatric Oncology
, Microbiology
, Physiology
, Molecular Oncology
, Gastroenterology
, Pharmacology
, Molecular biology
Research theme for competitive and other funds (9)： - 2024 - 2027 炎症性腸疾患におけるCircular RNA-RNA結合蛋白相互作用の解析
- 2022 - 2026 A basic research of developing novel preventions and treatments of Barrett's esophagus using bacteria-derived bioactive molecules
- 2022 - 2025 有益微生物由来分子を用いた小児白血病治療薬の開発の基盤研究
- 2021 - 2024 Identifications of bacteria-derived bioactive molecules that possess beneficial effects for extra-intestinal disorders
- 2021 - 2024 細菌由来の分子による腸ー肺連関メカニズムに基づいたARDS治療薬開発の基盤研究
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- Hiroaki Konishi, Takeshi Saito, Shuichiro Takahashi, Hiroki Tanaka, Katsuhiro Okuda, Hiroaki Akutsu, Tatsuya Dokoshi, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, et al. The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction. Scientific reports. 2025. 15. 1. 11919-11919
- Yuya Sugiyama, Hiroaki Konishi, Tatsuya Dokoshi, Hiroki Tanaka, Yu Kobayashi, Takahiro Sasaki, Koji Yamamoto, Aki Sakatani, Keitaro Takahashi, Katsuyoshi Ando, et al. hsa_circ_0015388 Reduces Macrophage Derived Reactive Oxygen Species in Crohn's Disease. Inflammatory bowel diseases. 2025
- Alex Q Lee, Hiroaki Konishi, Masami Ijiri, Yueju Li, Arun Panigrahi, Jeremy Chien, Noriko Satake. Therapeutic efficacy of RAS inhibitor trametinib using a juvenile myelomonocytic leukemia patient-derived xenograft model. Pediatric hematology and oncology. 2024. 41. 5. 367-375
- Keita Kojima, Hiroaki Konishi, Kyoka Momosaki, Yuya Komatani, Akira Katsuyama, Koji Nakagawa, Kayoko Kanamitsu, Fumika Yakushiji, Mikihiro Fujiya, Satoshi Ichikawa. Synthesis and biological evaluation of echinomycin analogues as potential colon cancer agent. Scientific reports. 2024. 14. 1. 7628-7628
- Takehito Kunogi, Hiroaki Konishi, Aki Sakatani, Kentaro Moriichi, Chikage Yamamura, Koji Yamamoto, Shin Kashima, Katsuyoshi Ando, Nobuhiro Ueno, Hiroki Tanaka, et al. Probiotic-derived ferrichrome induces DDIT3-mediated antitumor effects in esophageal cancer cells. Heliyon. 2024. 10. 6. e28070
- Hiroaki Konishi, Mikihiro Fujiya, Hiroki Tanaka, Toshikatsu Okumura. Ferrichrome, derived from probiotic bacteria, exerts an antitumor effect against colorectal cancer cells. CANCER SCIENCE. 2021. 112. 555-555
- Shotaro Isozaki, Mikihiro Fujiya, Hiroaki Konishi, Hiroki Tanaka, Yuuki Murakami, Yuya Sugiyama, Yu Kobayashi, Takahiro Sasaki, Takehito Kunogi, Keitaro Takahashi, et al. PROBIOTIC-DERIVED POLYPHOSPHATE IMPROVES DAMAGED INTESTINAL EPITHELIA THROUGH INDUCING PLATELET-DERIVED CELL GROWTH MOLECULES. GASTROENTEROLOGY. 2020. 158. 6. S501-S501
- Hiroaki Konishi, Mikihiro Fujiya, Akemi Kita, Hiroki Tanaka, Shin Kashima, Aki Sakatani, Tatsuya Dokoshi, Katsuyoshi Ando, Nobuhiro Ueno, Kentaro Moriichi, et al. ABNORMAL ACTIVATION OF HNRNPA0 INHIBITS CANCER CELL APOPTOSIS AND PROMOTES EXCESSIVE MITOSIS IN CANCER CELLS. GASTROENTEROLOGY. 2019. 156. 6. S484-S484
- Hiroaki Konishi, Mikihiro Fujiya, Masami Ijiri, Kazuyuki Tanaka, Shugo Fujibayashi, Takuma Goto, Shin Kashima, Katsuyoshi Ando, Keitaro Takahashi, Nobuhiro Ueno, et al. FERRICHROME, A TUMOR SUPPRESSIVE MOLECULE DERIVED FROM LACTOBACILLUS CASEI, INHIBITS THE PROGRESSION OF COLORECTAL CANCER VIA THE ENDOPLASMIC RETICULUM STRESS PATHWAY. GASTROENTEROLOGY. 2017. 152. 5. S253-S253
- K. Ando, M. Fujiya, H. Konishi, N. Ueno, K. Moriichi, H. Tanabe, E. Ichiishi, K. Sato, T. Otake, Y. Kohgo. Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) regulates epithelial apoptosis and restoration through binding with trefoil factor 2 (TFF2) messenger RNA in mice with anti-CD3-antibody-induced enteritis. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2015. 30. 38-38
- ペプチド系抗腫瘍薬の創製
- 抗腫瘍剤
- 血小板凝集剤
- ペプチド系抗腫瘍薬の創製
- 抗腫瘍剤
- 2012 - 2016 Asahikawa Medical University Graduate School of Medicine Doctoral Program in Medicine
- 2008 - 2010 Kyushu University Graduate School of Medical Sciences Master's Program in Medical Sciences
- 2004 - 2008 Hiroshima International University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
- 2024/04 - 現在 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Lecturer
- 2023/08 - 2024/03 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Assistant Professor
- 2022/08 - 2023/07 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Visiting Assistant Professor
- 2022/08 - 2023/07 University of California, Davis Department of Pediatrics Visiting Research Scholar
- 2018/05 - 2022/07 Asahikawa Medical University Department of Gastroenterology and Advanced Medical Sciences Assistant Professor
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- 2014/05 - AGA Digestive Disease Week 2014 Poster of Distinction
The Japanese Pharmacological Society
, The Japanese Cancer Association
, The Pharmaceutical Society of Japan
, Japan Society of Clinical Oncology
, The Japanese Society for Mucosal Immunology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.
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