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J-GLOBAL ID：202501007617202961
Update date: Feb. 11, 2025 Nakamura Jun
ナカムラ ジュン | Nakamura Jun
Osaka University Hospital
About Osaka University Hospital
Research theme for competitive and other funds (6)：
- 2023 - 2026 TRPC3/6を標的とした難治性かつ進行性腎疾患に対する新規治療薬開発
- 2024 - 2026 尿細管のTFEB-ANGPTL4軸に着目した、老化関連APOA4アミロイドーシスの病態解明
- 2023 - 2025 転写因子TFEBに着目した、老化関連腎アミロイドーシス抑制機構の解明
- 2020 - 2023 Strategies for delaying aging and age-related diseases focusing on autophagy suppressor Rubicon in the kidney
- 2023 - マグネシウムによるオートファジー改善を介した慢性腎臓病 患者のサルコペニア治療の試み
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- Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, et al. Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4-related amyloidosis. JCI insight. 2024
- Sho Matsui, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba-Hamano, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Jun Nakamura, et al. Empagliflozin protects the kidney by reducing toxic ALB (albumin) exposure and preventing autophagic stagnation in proximal tubules. Autophagy. 2024. 1-15
- Shihomi Maeda, Shinsuke Sakai, Yoshitsugu Takabatake, Takeshi Yamamoto, Satoshi Minami, Jun Nakamura, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, et al. MondoA and AKI and AKI-to-CKD Transition. Journal of the American Society of Nephrology : JASN. 2024. 35. 9. 1164-82
- Satoshi Minami, Shinsuke Sakai, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, Jun Nakamura, Shihomi Maeda, et al. FGF21 and autophagy coordinately counteract kidney disease progression during aging and obesity. Autophagy. 2024. 20. 3. 489-504
- Sho, Matsui, Tomoko, Namba-Hamano, Shihomi, Maeda, Jun, Nakamura, Atsushi, Takahashi, Jun-Ya, Kaimori, Shota, Fukae, Ryo, Tanaka, Ayumu, Taniguchi, Shigeaki, Nakazawa, et al. A Case Report of a Kidney Transplant Recipient With Organizing Pneumonia After Graft Loss. Transplantation Proceedings. 2023. 55. 1081-1083
- Jun Nakamura, Takeshi Yamamoto, Tomoko Namba, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Sho Matsui, Hideaki Kawai, Takuya Kubota, et al. Age-related Downregulation of TFEB Activity in Proximal Tubules Affects Systemic Lipid Metabolism and Causes ApolipoproteinA4-related Amyloidosis. Kidney Week 2024. 2024
- 中村隼, 山本毅士, 猪阪善隆. 加齢による近位尿細管のTFEB活性低下は全身の脂質代謝を増悪させる. 第54回 日本腎臓学会西部学術大会 シンポジウム5 若手が輝くメタボリックダイバーシティ!. 2024
- Jun Nakamura, Takeshi Yamamoto, Tomoko Namba, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Shihomi Maeda, Sho Matsui, Hideaki Kawai, Yoshitaka Isaka. Age-related Downregulation of TFEB Activity in Proximal Tubules Affects Systemic Lipid Metabolism and May Cause ApolipoproteinA4-related Amyloidosis. Kidney Health In Aging and Aged Societies: JSN/ERA Symposium Collaboration with JSDT. 2024
- TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney. 第67回日本腎臓学会学術総会 YIA(Young Investigator Award)受賞講演. 2024
- 中村隼, 山本毅士, 難波倫子, 高橋篤史, 松田潤, 南聡, 酒井晋介, 前田志穂美, 松井翔, 河合秀亮, et al. 加齢による近位尿細管のTFEB活性低下は,全身の脂質代謝を悪化させ,アミロイドーシスの原因となる. 第67回日本腎臓学会学術総会 優秀若手基礎研究者賞セッション. 2024
- Lipidomics: new insight into pathophysiology and therapeutic targets of kidney disease.
2023
- 2018 - 2023 大阪大学 大学院医学系研究科医学専攻 博士課程
- 2007 - 2013 Osaka University Faculty of Medicine
- 医学博士
- 2018/04 - 2025/03 大阪大学医学部附属病院 医員
- 2013/04 - 2018/03 大阪労災病院 研修医
- 2025 - 公益財団法人 国際医学研究振興財団 海外留学助成
- 2025 - 独立行政法人 日本学術振興会 海外特別研究員
- 2024 - Kidney Health In Aging and Aged Societies: JSN/ERA Symposium Collaboration with JSDT Travel Grant Award
- 2024 - 公益財団法人 持田記念医学薬学振興財団 留学補助金
- 2024 - 日本腎臓学会 第 10 回 Young Investigator Award
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