Rchr
J-GLOBAL ID：200901003605763666
Update date: Sep. 11, 2024
Uchiro Hiromi
ウチロ ヒロミ | Uchiro Hiromi
Affiliation and department：
Job title：
Professor
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (2)：
Organic Synthesis
, Synthetic Chemistry for Drug Discovery
Research theme for competitive and other funds (4)：
- 生理活性有機化合物の構造-活性相関に関する研究
- 生理活性有機化合物の新しい合成法に関する研究
- Studies on Structure-Activity Relationship of Bio-active Organic Compounds
- Studies on New Synthetic Method for Bio-active Organic Compounds
Papers (58)：
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Azuma M, Inoue M, Nishida A, Akahane H, Kitajima M, Natani S, Chimori R, Yoshimori A, Mano Y, Uchiro H, Tanuma S, Takasawa R. Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2021. 40. 127918
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Issei Takeuchi, Yuudai Kanno, Hiromi Uchiro, Kimiko Makino. Polyborane-encapsulated PEGylated Liposomes Prepared Using Post-insertion Technique for Boron Neutron Capture Therapy. J OLEO SCI. 2019. 68. 12. 1261-1270
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Tetsu Tsubogo, Saki Aoyama, Rika Takeda, Hiromi Uchiro. Synthesis of 2,2-Dialkyl Chromanes by Intramolecular Ullmann C-O Coupling Reactions toward the Total Synthesis of D-α-Tocopherol. Chemical and Pharmaceutical Bulletin. 2018. 66. 9. 843-846
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Yohsuke Shimada, Haruki Komaki, Ayako Hirai, Satoru Goto, Yasuyuki Hashimoto, Hiromi Uchiro, Hiroshi Terada. Decarboxylation of indomethacin induced by heat treatment. International Journal of Pharmaceutics. 2018. 545. 1-2. 51-56
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Issei Takeuchi, Nobuhiro Kishi, Kazutaka Shiokawa, Hiromi Uchiro, Kimiko Makino. Polyborane encapsulated liposomes prepared using pH gradient and reverse-phase evaporation for boron neutron capture therapy: biodistribution in tumor-bearing mice. Colloid and Polymer Science. 2018. 296. 7. 1137-1144
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MISC (1)：
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Glycosyntase : 変異酵素を利用する新しいグリコシル化反応. フォルマシア. 1999. 2
Books (4)：
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日本薬学会編 スタンダード薬学シリーズII3 化学系薬学 II.生体分子・医薬品の化学による理解
東京化学同人 2016 ISBN:9784807917068
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日本薬学会編 スタンダード薬学シリーズII3 化学系薬学 I.化学物質の性質と反応
東京化学同人 2015 ISBN:9784807917051
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日本薬学会編 スタンダード薬学シリーズ3 化学系薬学 I.化学物質の性質と反応
東京化学同人 2005
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創薬化学
東京化学同人 2004
Lectures and oral presentations (138)：
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強配位性単座配位子を用いたFinkelstein-Ullmannタンデム型C-Oカップリング反応の開発
(日本薬学会第144年会 2024)
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Claisen型転位反応を利用した2,3-二置換スクシンイミド類の新規合成法の開発
(日本薬学会第144年会 2024)
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抗腫瘍性物質Eucalyptal Aの全合成研究
(日本薬学会第144年会 2024)
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p97阻害活性物質Phomapyrrolidone Aの不斉全合成研究
(日本薬学会第144年会 2024)
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Phomapyrrolidone Aの四環性骨格部位の合成
(第85回有機合成化学協会関東支部シンポジウム 2023)
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Education (2)：
- - 1990 Tokyo University of Science Graduate School, Division of Natural Science Chemistry
- - 1988 Tokyo University of Science Faculty of Science
Professional career (1)：
- Doctor of Science (Tokyo Institute of Technology)
Work history (6)：
- 2008 - 2014 Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science Associate Professor
- 2014 - Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science Professor
- 2006 - 2008 Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science Associate Professor
- 1998 - 2006 Department of Medicinal Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science Lecturer
- 1992 - 1998 Basic Research Laboratories, Toray Industry Inc. Researcher
- 1995 - 1997 Division of Basic Science Research, Research Institute for Science and Technology, Tokyo Universityof Science Visiting Researcher
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Committee career (8)：
- 2012/04/01 - 2013/03/31 The Pharmaceutical Society of Japan, Kanto Branch Member of Steering Committee
- 2012/04/01 - 2013/03/31 日本薬学会関東支部 運営委員
- 2011/04/01 - 2012/03/31 The Pharmaceutical Society of Japan, Kanto Branch Member of Steering Committee
- 2011/04/01 - 2012/03/31 日本薬学会関東支部 運営委員
- 2010/04/01 - 2011/03/31 The Pharmaceutical Society of Japan, Kanto Branch Member of Steering Committee
- 2010/04/01 - 2011/03/31 日本薬学会関東支部 運営委員
- 2009/04/01 - 2010/03/31 The Pharmaceutical Society of Japan, Kanto Branch Member of Steering Committee
- 2009/04/01 - 2010/03/31 日本薬学会関東支部 運営委員
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Association Membership(s) (1)：
The Pharmaceutical Society of Japan, Kanto Branch
