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J-GLOBAL ID：200901018806569466   Update date: Nov. 18, 2024

Itoh Toshimasa

イトウ トシマサ | Itoh Toshimasa
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Affiliation and department：
Showa Pharmaceutical University Faculty of Pharmaceutical Sciences

About Showa Pharmaceutical University Faculty of Pharmaceutical Sciences


Job title： Associate Professor
Research field  (2)： Pharmaceuticals - chemistry and drug development ,  Structural biochemistry
Research keywords  (9)： 核内受容体 ,  NMR-構造解析 ,  X-線結晶構造解析 ,  構造生物学 ,  創薬化学 ,  Drug design ,  Fatty Acid ,  Nuclear Receptor ,  Structural Study
Research theme for competitive and other funds  (2)：
  • 2018 - 2021 A study of covalent modifier evaluation method using HDX
  • 2008 - 2010 Role of ligands for allosteric network of nuclear receptors
Papers (72)：
  • Tetsuya Yano, Takahiro Yamada, Hiroaki Isida, Nami Ohashi, Toshimasa Itoh. 2-cyanopyridine derivatives enable N-terminal cysteine bioconjugation and peptide bond cleavage of glutathione under aqueous and mild conditions. RSC Advances. 2024
  • Yuko Ishida, Erika Goto, Yuki Haga, Makoto Kubo, Toshimasa Itoh, Chie Kasai, Harunobu Tsuzuki, Miyune Nakamura, Osami Shoji, Keiko Yamamoto, et al. Enhanced metabolism of 2,3′,4,4′,5-pentachlorobiphenyl (CB118) by bacterial cytochrome P450 monooxygenase mutants of Bacillus megaterium. Science of The Total Environment. 2023. 890. 164475-164475
  • Hiroyuki Kojima, Ryota Yanagi, Eri Higuchi, Mami Yoshizawa, Tomoyuki Shimodaira, Misaki Kumagai, Tatsuhiro Kyoya, Miyu Sekine, Daichi Egawa, Nami Ohashi, et al. Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass Spectrometry. Journal of Medicinal Chemistry. 2023. 66. 7. 4827-4839
  • Miyu Sekine, Hiroaki Ishida, Toshimasa Itoh. Synthesis of Triazolo[c]coumarins and Differences in the Fluorescence Properties of Their Isomers. Asian Journal of Organic Chemistry. 2023. 12. 5
  • Terushi Ito, Chiharu Miwa, Yuki Haga, Makoto Kubo, Toshimasa Itoh, Keiko Yamamoto, Shintaro Mise, Erika Goto, Harunobu Tsuzuki, Chisato Matsumura, et al. Enantioselective metabolism of chiral polychlorinated biphenyl 2,2',3,4,4',5',6-Heptachlorobiphenyl (CB183) by human and rat CYP2B subfamilies. Chemosphere. 2022. 308. Pt 2. 136349-136349
ｍore...
MISC (6)：
  • 山本恵子, 穴見康昭, 清水伸隆, 浴本亨, 江川大地, 伊藤俊将, 池口満徳. SAXS-MD解析を用いたビタミンD受容体のアポ型及びアンタゴニスト結合型構造の解析. 日本薬学会年会要旨集(CD-ROM). 2017. 137th
  • 山本恵子, 斉藤智子, 伊藤俊将, 江川大地. 抗炎症メディエーター前駆体である17(S)-ヒドロキシドコサヘキサエン酸の簡便な合成法の確立. ビタミン. 2015. 89. 1
  • 穴見康昭, 清水伸隆, 浴本亨, 江川大地, 伊藤俊将, 池口満徳, 山本恵子. X線小角散乱(SAXS)と分子動力学計算(MD)を組み合わせたSAXS-MD法によるビタミンD受容体リガンド結合領域の相関構造解析. 日本薬学会関東支部大会講演要旨集. 2015. 59th
  • 穴見康昭, 江川大地, 伊藤俊将, 清水伸隆, 山本恵子. Bio-SAXSを用いた核内受容体の溶液構造の研究. 物構研サイエンスフェスタ要旨集. 2015. 3rd
  • 江川大地, 伊藤俊将, 片岡沙織, 星野咲季, 穴見康昭, 加藤晃, 山本恵子. X線結晶構造解析を用いたビタミンD受容体とコアクチベーターペプチドの結合様式解明. ビタミン. 2015. 89. 4
ｍore...
Education (5)：
  • 1999 - 2002 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
  • - 2002 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences Pharmacy
  • 1997 - 1999 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
  • 1993 - 1997 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy
  • - 1997 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science Pharmacy
Professional career (1)：
  • Doctor (Pharmacy) (Tokyo University of Pharmacy and Life Science)
Work history (6)：
  • 2006/06 - 2008/10 University of Leicester Biochemistry, Structural Biology Research Associate
  • 2005/04 - 2006/08 MRC-LMB Structural Study Visiting Scientist
  • 2006/03 - 2006/03 University of Debrecen, Biochemistry & Molecular Biology,
  • 2003/04 - 2006/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering
  • 2003/04 - 2006/03 JSPS Research Fellow
Show all
Association Membership(s) (5)：
日本レチノイド研究会 ,  日本薬学会 ,  Japanese Society for Retinoid Research ,  The Society of Synthetic Organic Chemistry ,  The Pharmaceutical Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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