
	Chemical structure search How to Search	Import MOLfile format is only available (V3000 format is not available) Exact match Substructure search Superstructure search Substructure or superstructure search Similarity search

Details
Related links
Search

Co-authoring Researcher

Co-inventing Researcher

Researcher similar to the Researcher

Article similar to the Researcher

Patent similar to the Researcher

Research Project similar to the Researcher

Article(J-GLOBAL estimation)

Patent(J-GLOBAL estimation)

Rchr

J-GLOBAL ID：200901020986488412 Update date: Mar. 12, 2025

Hirose Tetsuro

ヒロセテツロウ | Hirose Tetsuro

Clips

Affiliation and department：
Job title：教授
Homepage URL (1)： http://www.fbs.osaka-u.ac.jp/labs/hirose/

Research field (2)： Cell biology , Molecular biology

Research keywords (8)：ノンコーディングRNA , RNA顆粒 , 核内構造体 , エピジェネティックス , RNA結合タンパク質 , RNAスプライシング , ストレス応答 , 相分離

Research theme for competitive and other funds (36)：

2021 - 2026 Functional analysis of nondomain-type lncRNAs
2021 - 2026 Management of non-domain biopolymer research group
2020 - 2023 Decoding the code for the lncRNA function to induce intracellular phase separation
2020 - 2022 Inheritance mechanism of phase separated nuclear bodies built on noncoding RNAs
2019 - 2021 Molecular mechanism to induce intracellular phase separation by RNA tangling

2019 - 2020 Noncoding RNA Neo-taxonomy

2017 - 2020 Study on noncoding RNA-dependent architecture of nuclear 3D structure

2017 - 2019 Development of an RNA-induced protein phase separation system

2015 - 2019 Support activities to promote international collaboration to accomplish the research on noncoding RNA neo-taxonomy

2014 - 2019 Sequence and structure of ncRNA operation elements

2014 - 2019 Noncoding RNA neo-taxonomy

2014 - 2019 Neo-taxonomy of noncoding RNAs

2014 - 2017 Molecular mechanism of lncRNA-mediated architecture of subnuclear structures

2014 - 2016 Molecular basis of the noncoding RNA function that underlies species specificity

2008 - 2014 Comprehensive promotion of research on RNA program

2010 - 2013 Exhaustive prediction of microRNAs, snoRNAs and their targets

2011 - 2012 クロマチン上の非コードRNA複合体の単離法の開発

2008 - 2012 Regulation of gene expression and quality control via mRNA 3'-end processing

2011 - 2011 ノンコーディングRNAによる細胞内構造構築機序の解明

2008 - 2010 Small nuclear RNA-mediated mechanism to diversify the genetic information

2007 - 2009 新規核内RNAノックダウン法の確立

2005 - 2006 核内RNPリモデリングと品質管理機構の解明

2004 - 2006 哺乳類の核内exosomeによって制御されるRNA分子種の同定と機構解析

2005 - 2005 生体における組織特異的選択的スプライシング制御機構の解明

1999 - 2000 クロロプラストmRNAの多様な翻訳開始様式の全体像の解明

1998 - 2000 Functional analysis of chloroplast genes by chloroplast transformation

1999 - 1999 プラスチドの光合成関連遺伝子mRNAの新たな翻訳制御機構(RNAプロセシングの影響と翻訳産物によるフィードバック制御機構)

1997 - 1999 Studies on translation mechanisms of plastid mRNAs

1998 - 1998 葉緑体RNAエディティング酵素の同定と作用部位認識機構

1998 - 1998 プラスチドの光合成関連遺伝子mRNAの新たな翻訳抑制機構(RNAプロセシングの影響と翻訳産物によるフィードバック制御機構)

1997 - 1998 RNAプロセシングと翻訳過程における葉緑体遺伝子の特徴的な発現制御機構

1997 - 1997 葉緑体RNAエディティング酵素の同定と作用部位認識機構

1997 - 1997 光合成器官の形成と葉緑体機能の発現を制御する核遺伝子に関する研究

1996 - 1996 RNAプロセシングと翻訳過程における葉緑体遺伝子の特徴的な発現制御機構

1996 - 1996 光合成器官の形成と葉緑体機能の発現を制御する核遺伝子に関する研究

1995 - 1996 Study on the function of RNA0binding proteins of cyanobcteria and chloroplasts

Show all

Papers (132)：

Tsuyoshi Takashima, Chao Zeng, Eitaro Murakami, Naoko Fujiwara, Masaharu Kohara, Hideki Nagata, Zhaozu Feng, Ayako Sugai, Yasue Harada, Rika Ichijo, et al. Involvement of lncRNA MIR205HG in idiopathic pulmonary fibrosis and IL-33 regulation via Alu elements. JCI Insight. 2025. 10. 5
Hiro Takakuwa, Takao Yoda, Tomohiro Yamazaki, Tetsuro Hirose. Blocky proline/glutamine patterns in the SFPQ intrinsically disordered region dictate paraspeckle formation as a distinct membraneless organelle. 2025
Tetsuya Yamamoto, Tomohiro Yamazaki, Kensuke Ninomiya, Shinichi Nakagawa, Tetsuro Hirose. Biophysical aspect of assembly and regulation of nuclear bodies scaffolded by architectural RNA. Journal of Molecular Biology. 2025. 169016-169016
Hiro Takakuwa, Tetsuro Hirose. Speckle signatures dictate cancer prognosis. Nature Cell Biology. 2025
Ichiro Taniguchi, Tetsuro Hirose, Mutsuhito Ohno. The RNA helicase DDX39 contributes to the nuclear export of spliceosomal U snRNA by loading of PHAX onto RNA. Nucleic Acids Research. 2024

ｍore...

MISC (51)：

高生大希, 高桑央, 高桑央, 藤原奈央子, 岩切淳一, 浅井潔, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Effects of translation activity on accumulation of semi-extractable nuclear read-through transcripts DoGs. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
上野剛志, 足達俊吾, 二宮賢介, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Chained phosphorylation that drives thermo-sensitive splicing regulation by nuclear stress bodies. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
高桑央, 高桑央, 山崎智弘, SOUQUERE Sylvie, 足達俊吾, 藤原奈央子, 吉野彪羅, 山本哲也, 中川真一, 村上正晃, et al. Shell protein composition specified by NEAT1 domains dictates the paraspeckle segregation from nuclear speckles. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
角野愛美, 二宮賢介, 岩切淳一, 浅井潔, 廣瀬哲郎, 廣瀬哲郎, 廣瀬哲郎. Deciphering and recapitulating nuclear stress body assembly utilizing artificial HSATIII repeat RNAs. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
二宮賢介, 足達俊吾, 廣瀬哲郎, 廣瀬哲郎. The multifunctionality of HSATIII lncRNAs and its control mechanisms. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th

ｍore...

Lectures and oral presentations (4)：

Regulatory Mechanisms of Intracellular Organization and Gene Expression by Noncoding RNAs
(2022)
非コードRNAによる細胞内構造構築
(東京大学大学院新領域創成科学研究科セミナー 2022)
Construction mechanism of nuclear paraspeckle as an isolated RNP micell
(EMBO | EMBL Symposia: Cellular Mechanisms Driven by Liquid Phase Separation 2022)
Regulatory mechanisms of Intracellular Organization by noncoding RNAs

Professional career (1)：

理学博士

Work history (8)：

2020/04 - 現在 Osaka University Graduate School of Frontier Biosciences Professor
2013/09 - 2020/10 Hokkaido University Institute for Genetic Medicine
2013/04 - 2013/08 産業技術総合研究所バイオメディカル研究部門研究グループ長
2005/09 - 2013/03 産業技術総合研究所生物情報解析研究センター/バイオメディシナル情報研究センター研究チーム長
2004/04 - 2005/09 科学技術振興機構さきがけ専任研究員

Show all

Association Membership(s) (4)：

The RNA Society , JAPAN SOCIETY FOR CELL BIOLOGY , THE RNA SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page


	Free word	※Add the following synonyms, you can increase the number of hits.




		～