Rchr
J-GLOBAL ID:200901027018069567
Update date: Nov. 13, 2024
SEKINE Shun-ichi
関根 俊一 | SEKINE Shun-ichi
Affiliation and department:
Job title:
Team Leader
Research field (1):
Structural biochemistry
Research keywords (15):
CryoEM
, X線結晶構造解析
, クロマチン転写
, Viral replication
, RNAポリメラーゼ
, RNA polymerase II
, アミノアシルtRNA合成酵素
, セレノシステイン
, Cryo-EM
, X-ray crystallography
, Transcription
, RNA polymerase
, Translation
, tRNA
, Selenocysteine
Research theme for competitive and other funds (9):
- 2020 - 2025 植物の不均一環境変動へのレジリエンスを支える転写開始点制御機構
- 2020 - 2025 Structural basis of higher-order complexes connecting transcription and its related functions
- 2020 - 2024 RNAポリメラーゼを中心に形成される中核的複合体の構造基盤
- 2015 - 2020 Structural basis of RNA polymerase regulation by transcription factors
- 2011 - 2015 Structural and functional studies of multiple complexes of RNA polymerase
- 2008 - 2011 Crystallographic studies of macromolecular complexes in transcription and translation : RNA polymerases and the ribosome
- 2008 - 2011 Structural biology of the selenocysteine synthesis system.
- 2005 - 2006 転写終結複合体のX線結晶構造解析
- 2002 - 2003 ヒト由来グルタミルプロリルtRNA合成酵素のX線結晶構造解析
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Papers (106):
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Masahiro Shimizu, Hiroki Tanaka, Masahiro Nishimura, Nobuhiro Sato, Kayo Nozawa, Haruhiko Ehara, Shun-ichi Sekine, Ken Morishima, Rintaro Inoue, Yoshimasa Takizawa, et al. Asymmetric fluctuation of overlapping dinucleosome studied by cryoelectron microscopy and small-angle X-ray scattering. PNAS Nexus. 2024
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Tatsuo Yanagisawa, Yuko Murayama, Haruhiko Ehara, Mie Goto, Mari Aoki, Shun-ichi Sekine. Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nature Communications. 2024
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Tomoaki Kimura, Seiya Hirai, Tomoya Kujirai, Risa Fujita, Mitsuo Ogasawara, Haruhiko Ehara, Shun-Ichi Sekine, Yoshimasa Takizawa, Hitoshi Kurumizaka. Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes to cells : devoted to molecular & cellular mechanisms. 2024
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Yuxiang Liu, Ruixuan Wang, Qimingxing Chen, Yan Chang, Qi Chen, Kodai Fukumoto, Bingxun Wang, Jianchen Yu, Changfeng Luo, Jiayuan Ma, et al. Organ-Specific Gene Expression Control Using DNA Origami-Based Nanodevices. Nano Letters. 2024. 24. 27. 8410-8417
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Takako Ohyama, Takuo Osawa, Shun-ichi Sekine, Yoshitaka Ishii. NMR Studies of Genomic RNA in 3′ Untranslated Region Unveil Pseudoknot Structure that Initiates Viral RNA Replication in SARS-CoV-2. JACS Au. 2024
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MISC (5):
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苫米地由里, 井上敏, 細谷孝充, 関根俊一, 白水美香子. 発光反応の遅い半合成cf3-イクオリンの結晶構造解析. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st
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伊藤弓弦, 伊藤弓弦, 関根俊一, 関根俊一, 松本英子, 赤坂領吾, 竹本千重, 白水美香子, 横山茂之, 横山茂之. セレノリン酸合成酵素の構造解析. 生化学. 2008
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上西達也, 川添将仁, 竹本千重, 齋藤由美, 関根俊一, 白水美香子, WILSON Daniel N., FUCINI Paola, 横山茂之, 横山茂之. 高度好熱菌リボソーム複合体の結晶構造解析. PFシンポジウム要旨集. 2007. 24th
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別所義隆, 柴田理恵, 村山和隆, 村山和隆, 関根俊一, 関根俊一, 東島今日子, 竹本千重, 白水美香子, 倉光成紀, et al. 好熱菌tmRNA-tRNAドメインの結晶構造解析. RNAミーティング. 2005. 7th
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川添将仁, 竹本(堀)千重, 上西達也, 関根俊一, 白水美香子, 横山茂之. 高度好熱菌Eraの構造と機能の解析. 日本分子生物学会年会プログラム・講演要旨集. 2004. 27th
Education (3):
- The University of Tokyo Graduate School of Science
- Tohoku University
- University of Tokyo
Professional career (1):
Work history (8):
Association Membership(s) (2):
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