Uchida Takafumi

ウチダタカフミ | Uchida Takafumi

Affiliation and department：
Job title： Emeritus Professor
Other affiliations (1)：

Showa University Visiting Professor

Research field (5)： Molecular biochemistry , Neuropathology , Tumor biology , Pharmaceuticals - chemistry and drug development , Applied molecular and cellular biology

Research keywords (13)： Prolyl Isomerase Pin1 , Gas7 , p53 , c-Myc , Tau , microtubule , polyphenols , Alzheimer's disease , Cancer , Mesenchymal stem cells , Prolyl isomerase Par14 , Protein Phosphorylation , Uridine phosphorylase

Research theme for competitive and other funds (19)：

2014 - 2020 Prevention, diagnosis and drug discovery of aging diseases using Pin1 related molecules
2016 - 2019 Role of Pin1 in the development of pulmonary hypertension and therapeutic application
2015 - 2018 Is inducion of osteoblasts proliferation useful to treat the osteporosis patients?
2014 - 2017 Mechanisms of symbiotic evolution and N2O mitigation of soybean bradyrhizobia
2014 - 2017 Preparation for PTD-Pin1 and its appllication to stem cell differentiation

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Papers (128)：

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MISC (215)：

Ohtaki H, Ono K, Tanaka M, Setoguchi Y, Hayashi A, Yoshikawa A, Kang D, Honda K, Kakita A, Uchida T. Amyloid-positive particles in pin1 KO mice are resemble with eosinophilic thalamic body in human. Society for Neuroscience. 2022
柏木美麗, 橋本真祐, 高橋勝彦, 植松優希, 紺澤咲乃, 山本みな美, 中嶋彩乃, 内田隆史, 東伸昭. Retinoic acid regulates activation of AMPK in MCD-induced NASH. 日本薬学会年会要旨集(Web). 2022. 142年会. 26PO8-05S
Gissi C, Zuccarelli L, Comelli M, Brocca L, Rossi M, Battini R, Uchida T, Pellegrino M.A, Bottinelli R, Grassi B, et al. Increased MtCK and ANT1 in aging Pin1 KO mice as a basis of augmented ADP sensitivity of mitochondrial respiration. 61th italian society of biochemistry and molecular biology. 2021
岡田拓実, 内田千代子, 内田隆史. Analysis of Molecular Mechanism behind the effect of miso on the increase of resiliency. 中央味噌研究所研究報告. 2020. 41. 49-52
大滝博和, 田中優希, 内田隆史, 桐山恵介, 本田一穂. Pin1KOマウスにおける視床に増加するβアミロイド陽性反応の経時的解析. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2020. 125th

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Patents (12)：

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Books (4)：

“Luminescence Biotechnology: Instruments and Applications”
CRC Press LLC (New York) 2002
Polymers in Medicine
Plenum Publishing Co. (New York) 1986
Macrophage Biology
Alan R. Liss, Inc. (New York) 1985
免疫実験操作法, XIII
1984

Education (4)：

1985 - The University of Tokyo, Graduate School Ph.D.
1977 - 1979 The University of Tokyo, Graduate School Applied Biochemistry MS
1975 - 1977 The University of Tokyo Biochemistry
1973 - 1975 The University of Tokyo Science

Professional career (1)：

PhD (The University of Tokyo)

Work history (21)：

2019/04 - 現在 Showa University School of Pharmacy visiting professor
2019/04 - 現在 Tokyo Kasei University
2019/04 - 現在 Tohoku University Emeritus Professor
2019/04 - 2021/03 Hoshi University
2019/04 - 2020/03 Kanagawa University

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Committee career (7)：

2020/04 - 現在オープンイノベーション研究・実用化推進事業評議委員
2002/04 - 現在独立行政法人日本学術振興会独立行政法人日本学術振興会審査委員
2000/09 - 現在 Nakajima Foundation Selection Committee
2018/09 - 2023/03 Japan Biochemistry Association Deputy
2000/09 - 2020/03 Nakajima Foundation councilor

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Awards (4)：

2007/03 - 日本農芸化学会研究企画賞 Search for phosphorylated protein-specific proline isomerase Pin1 regulator from natural products
2000/03 - AACR Scholar in Training Award
1987/04 - Yale Univ. SCM James Hudson Brown - Alexander B. Cox Fellowship
1984/09 - Basic Research Institute, Toray Industries The Best Patent, The best paper microbeads for biological tests

Association Membership(s) (7)：

日本生化学会 , 日本農芸化学会 , ASBMB , 日本分子生物学会 , 日本癌学会 , American Association for Cancer Research , Society for Neuroscience

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