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J-GLOBAL ID：200901050698195814 Update date: Mar. 25, 2025

Yoshifuji Hajime

ヨシフジハジメ | Yoshifuji Hajime

Affiliation and department：
Job title： Lecturer (Assistant Professor)
Homepage URL (1)： http://www.rheum.kuhp.kyoto-u.ac.jp/research/yoshifuji

Research field (2)： Immunology , Allergies and connective tissue disease

Research keywords (10)： Pulmonary hypertension , Systemic autoimmune disease , Castleman's disease , relapsing polychondritis , IgG4-related disease , Takayasu arteritis , Vasculitis , Connective tissue disease , Rheumatic diseases , Polymyositis/Dermatomyositis

Research theme for competitive and other funds (30)：

2019 - 2024 Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease
2020 - 2023 Improvement of IgG4-related disease model and its treatments
2019 - 2020 再発性多発軟骨炎の自己抗体および末梢血プロファイルの解析
2019 - 2020 トシリズマブ効果不十分の特発性多中心性キャッスルマン病に対するシロリムスの医師主導治験
2019 - 2020 ゲノム・転写物・代謝物を融合した統合オミックス解析による稀少難治性疾患の病態解明

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Papers (220)：

Yuto Nakakubo, Hideaki Tsuji, Yudai Takase, Tsuneyasu Yoshida, Tomohiro Kozuki, Takeshi Iwasaki, Mirei Shirakashi, Hideo Onizawa, Ryosuke Hiwa, Koji Kitagori, et al. The Association of Anti-dsDNA Antibodies with Patient-reported Outcomes of Patients with Systemic Lupus Erythematosus in a Two-consecutive Year Prospective Study. The Kobe journal of medical sciences. 2025. 70. 4. E113-E124
Takahiko Sugihara, Masayoshi Harigai, Haruhito A. Uchida, Hajime Yoshifuji, Yasuhiro Maejima, Jun Ishizaki, Yoshiko Watanabe, Hiroaki Dobashi, Yoshinori Komagata, Naoto Tamura, et al. Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis. Arthritis Research & Therapy. 2025. 27. 1
Hajime Yoshifuji, Tomonori Ishii, Hiroki Ohashi, Katsunori Yoshizawa, Maki Mihoya, Kazuko Nishikawa, Yoshikazu Nakaoka. Phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group study of ustekinumab in patients with Takayasu arteritis. Rheumatology advances in practice. 2025. 9. 2. rkaf013
Takeshi Iwasaki, Hajime Yoshifuji, Koji Kitagori, Shuji Sumitomo, Shuji Akizuki, Ran Nakashima, Hideaki Tsuji, Ryosuke Hiwa, Mirei Shirakashi, Kosaku Murakami, et al. Memory B cells and their transcriptomic profiles associated with belimumab resistance in systemic lupus erythematosus in the maintenance phase. Frontiers in immunology. 2025. 16. 1506298-1506298
Motohisa Yamamoto, Masatoshi Kanda, Ichiro Mizushima, Atsushi Kanno, Takeji Umemura, Tsukasa Ikeura, Yuzo Kodama, Hiroaki Dobashi, Yoshiya Tanaka, Atsushi Masamune, et al. Clinical profile of IgG4-related disease in Japan based on the rare disease data registry. Immunological Medicine. 2024. 1-11

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MISC (274)：

藤野麻琴, 川島雅央, 松本純明, 川口展子, 森由希子, 山口絢音, 河口浩介, 高田正泰, 戸井雅和, 吉藤元, et al. 乳癌術後に著明な緩解に至った内科的治療抵抗性重症皮膚筋炎の一症例. 第30回日本乳癌学会学術総会. 2022. 30回. EP28-285
吉田常恭, 吉藤元, 白柏魅怜, 村上孝作, 森信暁雄. 再発性多発軟骨炎の再発因子に関する後方視的検討. 日本内科学会雑誌. 2021. 110
Hajime Yoshifuji, Haruhito Uchida, Yoshikazu Nakaoka, Takahiko Sugihara, Mitsuaki Isobe, Masayoshi Harigai. Long-term Clinical Course and Outcomes of 2013 Patients with Takayasu Arteritis. ARTHRITIS & RHEUMATOLOGY. 2019. 71
Tsuneo Sasai, Ran Nanashima, Tsuneyo Mimori, Hideaki Tsuji, Shuji Akizuki, Kosaku Murakami, Motomu Hashimoto, Hajime Yoshifuji, Masao Tanaka, Koichiro Ohmura. Maintenance Therapy for anti-MDA5-Positive Dermatomyositis Patients with Interstitial Lung Disease: Can They Achieve Drug-Free Remission?. ARTHRITIS & RHEUMATOLOGY. 2019. 71
吉藤元. 血管炎症候群の分類と病態. 日本小児リウマチ学会総会・学術集会プログラム・抄録集. 2019. 29回. 77-77

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Lectures and oral presentations (39)：

EGPAの基礎・病態・治療
(GSK EGPA web Seminar 2019)
膠原病合併肺高血圧症の治療〜疾患概念の曖昧さを考える〜
(第6回湖北肺高血圧症フォーラム 2019)
膠原病合併肺高血圧症の病態と治療
(第2回周南医療圏徳山医師会学術講演会 2019)
高齢者の血管炎の病態と治療戦略
(高知膠原病・リウマチセミナー 2019)
CTD-PAH -診断における注意点と病態-
(第6回鹿児島PAH講演会 2019)

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Education (2)：

2000 - 2004 Kyoto University Graduate School of Medicine Rheumatology and Clinical Immunology
1991 - 1997 Kyoto University Faculty of Medicine

Professional career (1)：

M.D., Ph.D (Kyoto University)

Work history (8)：

2020/08 - 現在 Kyoto University Department of Rheumatology and Clinical Immunology, Graduate School of Medicine Lecturer/Assistant Professor
2014/06 - 2020/08 Kyoto University Hospital Rheumatology and Clinical Immunology Lecturer (Assistant Professor)
2010/08 - 2014/05 Kyoto University Department of Rheumatology and Clinical Immunology, Graduate School of Medicine Assistant Professor
2008/06 - 2010/07 Feinstein Institute for Medical Research Center for Autoimmune and Musculoskeletal Diseases Postdoctoral research fellow
2006/08 - 2008/05 Kyoto University Hospital Rheumatolofy and Clinical Immunology Assistant Professor

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Association Membership(s) (13)：

日本臨床免疫学会 , 日本免疫学会 , 日本リウマチ学会 , 日本内科学会 , Japan Society for Clinical Immunology , Japanese Society for Immunology , Japan College of Rheumatology , The Japanese Society of Internal Medicine , American College of Rheumatology , 日本シェーグレン症候群学会 , 日本IgG4関連疾患学会 , 日本炎症再生学会 , 日本肺高血圧肺循環学会

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