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Rchr
J-GLOBAL ID：200901053550435467
Update date: Mar. 12, 2025 Takemoto Yasushi
タケモト ヤスシ | Takemoto Yasushi
ClipsPapers (24)
- Misao Takemoto, Sara Delghandi, Masahiro Abo, Keiko Yurimoto, Minami Odagi, Vaibhav Pal Singh, Jun Wang, Reiko Nakagawa, Shin-ichi Sato, Yasushi Takemoto, et al. Covalent Plant Natural Product that Potentiates Antitumor Immunity. Journal of the American Chemical Society. 2025. 147. 3. 2902-2912
- Fumihiro Kawagoe, Sayuri Mototani, Yasushi Takemoto, Motonari Uesugi, Atsushi Kittaka. An Improved and Scalable Synthesis of the Potent SREBP Inhibitor KK-052 via [3+2] Cycloaddition. Synthesis. 2024. 56. 09. 1460-1464
- Fumihiro Kawagoe, Sayuri Mototani, Aileen Mendoza, Yasushi Takemoto, Motonari Uesugi, Atsushi Kittaka. Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052. RSC Medicinal Chemistry. 2023. 14. 2030-2034
- Shuyu Jin, Shao-hua Zhuo, Yasushi Takemoto, Yan-mei Li, Motonari Uesugi. Self-assembling small-molecule adjuvants as antigen nano-carriers. Chemical Communications. 2022. 58. 87. 12228-12231
- Aileen Mendoza, Yasushi Takemoto, Kevin Tan Cruzado, Shadi Sedghi Masoud, Akiko Nagata, Ajcharapan Tantipanjaporn, Satoshi Okuda, Fumihiro Kawagoe, Ryota Sakamoto, Minami Odagi, et al. Controlled lipid β-oxidation and carnitine biosynthesis by a vitamin D metabolite. Cell Chemical Biology. 2022. 29. 4. 660-669.e12
- Yasushi Takemoto, Shin Kadota, Itsunari Minami, Shinya Otsuka, Satoshi Okuda, Masahiro Abo, Louvy Lynn Punzalan, Yan Shen, Yuji Shiba, Motonari Uesugi. Chemical Genetics Reveals a Role of Squalene Synthase in TGFβ Signaling and Cardiomyogenesis. Angewandte Chemie International Edition. 2021. 60. 40. 21824-21831
- Fumihiro Kawagoe, Aileen Mendoza, Yuki Hayata, Lisa Asano, Kenjiro Kotake, Sayuri Mototani, Satoshi Kawamura, Shigeyuki Kurosaki, Yusuke Akagi, Yasushi Takemoto, et al. Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo. Journal of Medicinal Chemistry. 2021. 64. 9. 5689-5709
- Louvy Lynn Punzalan, Lulu Jiang, Di Mao, Amarjyoti Das Mahapatra, Shinichi Sato, Yasushi Takemoto, Mari Tsujimura, Kosuke Kusamori, Makiya Nishikawa, Lu Zhou, et al. Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library. Cell Chemical Biology. 2020. 27. 6. 708-718.e10
- Yasushi Takemoto, Di Mao, Louvy Lynn Punzalan, Sebastian Götze, Shin-Ichi Sato, Motonari Uesugi. Discovery of a Small-Molecule-Dependent Photolytic Peptide. Journal of the American Chemical Society. 2020. 142. 3. 1142-1146
- Akiko Nagata, Yusuke Akagi, Lisa Asano, Kenjiro Kotake, Fumihiro Kawagoe, Aileen Mendoza, Shadi Sedghi Masoud, Kosuke Usuda, Koji Yasui, Yasushi Takemoto, et al. Synthetic Chemical Probes That Dissect Vitamin D Activities. ACS chemical biology. 2019. 14. 12. 2851-2858
- Di Mao, Xie Khim Watson Chung, Tomoko Andoh-Noda, Ying Qin, Shin-Ichi Sato, Yasushi Takemoto, Wado Akamatsu, Hideyuki Okano, Motonari Uesugi. Chemical decontamination of iPS cell-derived neural cell mixtures. Chemical Communications. 2018. 54. 11. 1355-1358
- Yasushi Takemoto, Akihiro Ito, Hideaki Niwa, Mutsumi Okamura, Takashi Fujiwara, Tomoya Hirano, Noriko Handa, Takashi Umehara, Takeshi Sonoda, Kenji Ogawa, et al. Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription. JOURNAL OF MEDICINAL CHEMISTRY. 2016. 59. 8. 3650-3660
- Andrei Ursu, Damir J. Illich, Yasushi Takemoto, Arthur T. Porfetye, Miao Zhang, Andreas Brockmeyer, Petra Janning, Nobumoto Watanabe, Hiroyuki Osada, Ingrid R. Vetter, et al. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. CELL CHEMICAL BIOLOGY. 2016. 23. 4. 494-507
- Shigeyuki Magi, Yasushi Takemoto, Hiroki Kobayashi, Masato Kasamatsu, Takahiro Akita, Ayako Tanaka, Kei Takano, Etsu Tashiro, Yasuhiro Igarashi, Masaya Imoto. 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor- induced cell migration through Tiam1 upregulation and Rac1 activation. CANCER SCIENCE. 2014. 105. 3. 290-296
- Hongfang Chi, Yasushi Takemoto, Tienabe K. Nsiama, Tamaki Kato, Norikazu Nishino, Akihiro Ito, Minoru Yoshida. Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY. 2014. 22. 4. 1268-1275
- Shigeyuki Magi, Tetsuo Shitara, Yasushi Takemoto, Masato Sawada, Mitsuhiro Kitagawa, Etsu Tashiro, Yoshikazu Takahashi, Masaya Imoto. Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase. JOURNAL OF ANTIBIOTICS. 2013. 66. 3. 165-170
- Masanari Takahashi, Yasushi Takemoto, Tadahiro Shimazu, Hisashi Kawasaki, Makoto Tachibana, Yoichi Shinkai, Motoki Takagi, Kazuo Shin-ya, Yasuhiro Igarashi, Akihiro Ito, et al. Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines. JOURNAL OF ANTIBIOTICS. 2012. 65. 5. 263-265
- Yi Sun, Kentaro Takada, Yasushi Takemoto, Minoru Yoshida, Yuichi Nogi, Shigeru Okada, Shigeki Matsunaga. Gliotoxin Analogues from a Marine-Derived Fungus, Penicillium sp., and Their Cytotoxic and Histone Methyltransferase Inhibitory Activities. JOURNAL OF NATURAL PRODUCTS. 2012. 75. 1. 111-114
- Hiroki Kobayashi, Yusuke Ogura, Masato Sawada, Ryoji Nakayama, Kei Takano, Yusuke Minato, Yasushi Takemoto, Etsu Tashiro, Hidenori Watanabe, Masaya Imoto. Involvement of 14-3-3 Proteins in the Second Epidermal Growth Factor-induced Wave of Rac1 Activation in the Process of Cell Migration. JOURNAL OF BIOLOGICAL CHEMISTRY. 2011. 286. 45. 39259-39268
- Masato Sawada, Shin-ichiro Kubo, Koji Matsumura, Yasushi Takemoto, Hiroki Kobayashi, Etsu Tashiro, Takeshi Kitahara, Hidenori Watanabe, Masaya Imoto. Synthesis and anti-migrative evaluation of moverastin derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2011. 21. 5. 1385-1389
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