Research field (5)：
Applied biofunctional and bioprocess engineering
, Transfer phenomena and unit operations
, Biomaterials
, Analytical chemistry
, Nano/micro-systems
Research keywords (4)：
粒子・流体プロセス
, 生物化学工学
, 生体組織工学
, マイクロ・ナノ流体デバイス
Research theme for competitive and other funds (22)：
2023 - 2026 「硬さ」を計測し操作する造血幹細胞の増殖・分化制御系
2022 - 2025 ヒト赤血球型第4世代PFC人工酸素運搬体の開発
2022 - 2025 高密度3次元微細孔を利用するマルチパラメーター細胞分離システム
2020 - 2023 Demonstration of an integrated cell processing device that revolutionizes minimally invasive prenatal diagnosis
2020 - 2023 Precise reconstruction of complex biological tissue by flexible processing of "porous" matrix
2019 - 2022 Demonstration of a multiscale fluid separator that revolutionizes next-generation liquid biopsy
2018 - 2021 Construction and functional expression of 3-dimensional vascularized liver tissue models by innovations in materials, processes, and devices
2017 - 2020 Demonstration of integrated microfluidic system that realizes selection / placement / 3-dimensional complex of cells
2016 - 2019 Reproduction processes of three-dimensional tissues based on particulate matrices
2015 - 2019 Formation of functional 3D tissues suitable for transplantation by liver and pancreatic cells
2016 - 2018 Development of Assay Systems for Cancer Cell Invasion Using Microfabricated Hierarchical Hydrogels
2014 - 2017 Development and Application of Integrated Micro Cell-Sorting System Enabling High-Throughput Treatment
2014 - 2016 Creation of iPS-derived Hepatocyte-based Therapeutic Modality Using Liver Micro-organoids
2011 - 2016 High speed cell assembly using microfluidics
2013 - 2015 Reconstruction of high-density tissues utilizing complex cellular aggregates and microfabricated hyrdogels
2011 - 2013 Development of continuous separation systems using monodisperse microbubbles
2011 - 2012 Fabrication of Complex Hydrogel Materials with Microscale Patterns for Cell Organization
2008 - 2011 Investigation of Rapid and Continuous Separation Principle for Micro/Nano Structures Using Hydrodynamic Methods
2008 - 2010 Preparation of Non-spherical Cell-containing Hydrogel Materials Using Microscale Aqueous Multi-phase Systems
Shota Mashiyama, Runa Hemmi, Takeru Sato, Atsuya Kato, Tatsuo Taniguchi, Masumi Yamada. Pushing the limits of microfluidic droplet production efficiency: engineering microchannels with seamlessly implemented 3D inverse colloidal crystals. Lab on a Chip. 2024. 24. 2. 171-181
Yuken Hasebe, Masumi Yamada, Rie Utoh, Minoru Seki. Expansion of Chinese hamster ovary cells via a loose cluster-assisted suspension culture using cell-sized gelatin microcarriers. Journal of Bioscience and Bioengineering. 2023. 135. 5. 417-422
Mai Takagi, Masumi Yamada, Rie Utoh, Minoru Seki. A multiscale, vertical-flow perfusion system with integrated porous microchambers for upgrading multicellular spheroid culture. Lab on a Chip. 2023. 23. 9. 2257-2267
Natsumi Shimmyo, Makoto Furuhata, Masumi Yamada, Rie Utoh, Minoru Seki. Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells. Analyst. 2022. 147. 8. 1622-1630
Hideki Iwadate, Naoki Kimura, Rina Hashimoto, Yuya Yajima, Rie Utoh, Masumi Yamada, Minoru Seki. Basement membrane-mimetic microengineered ECM films for cell co-culture on front-back surfaces. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. 2020. 177-178
Mayu Fukushi, Yuya Yajima, Rie Utoh, Masumi Yamada, Kazuya Furusawa, Minoru Seki. Collagen gelation on phosphate particle-embedding PDMS (PP-PDMS) channel: An efficient approach to vascular tissue engineering. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. 2020. 1145-1146
Natsumi Shimmyo, Makoto Furuhata, Masumi Yamada, Rie Utoh, Minoru Seki. Parallelized microfluidic thin cell trappers for effectively selecting blood circulating tumor cells. MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. 2020. 1155-1156
