Nishimura Masahiro

2021 - 2024 口腔保湿剤を用いた新規口腔カンジダ症の治療戦略

2021 - 2024 細胞内エネルギー代謝調節による顎骨骨髄間葉系幹細胞の分化制御機構の解明

2021 - 2024 高齢ドナー顎骨由来MSCを用いたSASP抑制による高度顎堤吸収治療法の開発研究

2021 - 2024 口腔機能低下とフレイルを予防するためのコホート研究と情報共有ツールの開発

2021 - 2024 ジェルコート保湿による新規保湿法の開発と多軸的評価

2023 - 2024 移植後に確実に骨を形成する新規骨再生剤の開発

2022 - 2024 顎骨再建のための多機能性骨被覆材の開発

2020 - 2023 Fundamental research for realizing regenerative medicine using jaw bone marrow mesenchymal stem cells

2020 - 2023 間葉系幹細胞-析出型アパタイト複合体を用いた垂直/水平的大規模顎骨増生法の開発

2020 - 2023 下顎無歯顎に応用する軟質リライン材の臨床効果 -多施設ランダム化比較試験-

2019 - 2022 人工骨-粘膜複合体による新規顎堤再建法の開発

2019 - 2022 顎骨骨髄間質細胞を用いた顎骨再医療のための骨形成能診断法の開発

2019 - 2022 高齢ドナー由来間葉系幹細胞を用いた骨増生時における細菌由来因子影響の解析研究

2019 - 2022 顎骨骨髄炎発症要因における歯原性細胞と細胞極性調節因子相互作用の解析

2018 - 2022 骨成長因子・骨再生材料を用いた唇顎口蓋裂患者の顎裂部骨移植術の臨床的研究

2018 - 2021 Development and Multiaxial Evaluation of a Temperature-Controlled moisturizing Method.

2018 - 2021 Development of novel mandibular bone augmentation therapy using exosomes derived from mandibular/maxillary bone marrow derived mesenchymal stem cells

2018 - 2021 Developmental research of a severe bone resorption therapy by using MSCs via autophagic modulation

2017 - 2020 Fusion of in situ bacteriology of tissue regeneration area around implant body

2017 - 2020 Development of regenerative therapy for peri-implantitis using diabetic model

2017 - 2020 Development and multiaxial evaluation of a newly xerostomia treatment using Glucosylceramide Extracted from Pineapple

2017 - 2020 Multiple control and visualization of self-somatic- stem cells for atrophic jaw bone augmentation

2016 - 2020 Intraosseous Changes in Next-Generation Bioabsorbable Hydroxyapatite Surface-Coated Magnesium Alloys

2016 - 2019 Development of alveolar bone augmentation by nerve guidance

2016 - 2019 Search for new specific molecular markers that can predict bone regenerative ability of mandible bone marrow stem cells.

2016 - 2019 Development of custom-made bone making method using bone replacement type material

2016 - 2019 Development of mouth moisturizer with functions of acceleration of salivary secretion and activation of mucosa for denture patients with dry mouth

2015 - 2018 Relationship between the reduction of bone regeneration and angiogenic potential in the senescence-associated mesenchymal stem cells.

2015 - 2018 Development and evaluation on its effectiveness of new moisturizing method by combination moisturizing

2015 - 2018 Invetigation of denture plaque attachment inhibitationin order to ease the imposition by care

2014 - 2017 Development of a multi-function soft denture liner having bFGF-controlled release and self-cleaning functions

2014 - 2017 Recovery of chewing ability in dry mouth patients with denture wearers normalizes oral flora

2014 - 2017 Development of a novel orofacial bone regenerative method depending on the angiogenesis and lymphangiogenesis.

2013 - 2017 Bone engineering with gene activated-matrix and non-cultured adipose cells

2014 - 2017 Mechanical and histrogical analysis bone to implant contact in type2 diabetes rats model with antidiabetic drugs.

2014 - 2016 Development of bone scaffold for periosteum self-lifting

2013 - 2016 Development of the diagnostic method using maxilla/mandibular bone marrow stromal cells for alveolar ridge augmentation

2013 - 2016 Bone regeneration with bone substitute and cells in osteoclast lineage

2015 - 2016 ソウハクヒ成分含有剤による褥瘡・皮膚潰瘍治療効果の検討

2013 - 2015 Delivery of functional microRNA accelerates the bone regeneration with BMP2 and BMAC.

2012 - 2015 Effective moisturizing is to normalize the oral and pharynx flora of dry mouth patients

2012 - 2015 Development of a mouth moisturizer using the colloidal platinum and chymase inhibitor.

2012 - 2014 Development of polymer materials for ultralow invasive periosteum lifting

2011 - 2014 Development of a fluorinated tissue conditioner with high durability and healing acceleration function by bioactive substances

2010 - 2014 Tooth-derived mesenchymal cells as a cell replacement source in the treatment of neurological

2010 - 2012 Jaw bone regeneration using gene activated matrix incorporated withdirectly prepared adipose derived stem cells

2010 - 2012 Alveolar bone engineering using alveolar bone marrow derived mesenchymal stem cells

2010 - 2011 Selection of osteogenic progenitor cells in gingival tissue

2009 - 2010 補綴物の予知性を高めるための非外科的角化歯肉拡大法の開発

2008 - 2009 開業歯科医院に普及可能な顎骨骨髄採取法および採取した骨髄液から確実に間葉系幹細胞を培養・保存する方法の開発

2007 - 2009 Relationship between psychological stress evaluated by salivary Chromogranin and oral habits

2007 - 2009 間葉系幹細胞(MSC)の安全性判定法とそれを用いた細胞治療法の事業化

2007 - 2009 Development of alveolar bone regenerative medicine using regulated autologous cells

2008 - 2008 歯科インプラントを可能にするためのMSCによる歯槽骨増生法の開発

2006 - 2008 Isolation of stem cells for alveolar ridge augmentation from oral tissues

2006 - 2007 再生医療を普及させる細胞/担体移植体のカプセル化

2007 - 2007 歯科インプラントを可能にするためのMSCによる歯槽骨増生法に関する調査

2006 - 2007 Approach to get mineralized tissue using pulp cells

2004 - 2007 Influence of denture wearing of elderly with dementia on the state of dementia, general health, and QOL

2004 - 2006 抗菌ペプチドを用いた再生医療用幹細胞の大量増殖技術の開発

2005 - 2006 高度吸収顎堤再生のための高齢者向け非細胞性骨造成法の開発

2003 - 2005 歯周病と骨疾患に対する細胞治療の事業化:幹細胞治療法のシステム化

2004 - 2005 Development of a moisturized soft denture liner for a patient having dry mouth

2003 - 2004 高度吸収顎堤再生のための注入可能な間葉系幹細胞/担体複合体の開発

2003 - 2004 Development of visible light-polymerized, resilient denture liners with high durability

2002 - 2003 間葉系幹細胞及び上皮細胞の超増幅法

2002 - 2003 Molecular pattern recognition of oral epithelial cells against pathogenic organisms

2001 - 2003 Longitudinal study of the stage of dementia, the health status, the living environment, and oral status in elderly people with dementia

2001 - 2002 Antifungal activity of Lactoferricins and their derivatives

2001 - 2002 骨誘導能をもつシラン処理チタン材料の開発

1999 - 2000 Factors involved in the interactions of Candida albicans and oral bacteria

1999 - 2000 Cariogenicity of Denture Plaque

1998 - 1999 Factors involved in the interactions, of Candida albicans and oral bacteria

1996 - 1997 Studies on development of new types of spacers with marked reducing ability on radiation dose