Rchr
J-GLOBAL ID：200901084336442505   Update date: Apr. 05, 2024

Uchihashi Takayuki

Uchihashi Takayuki
Affiliation and department：
Nagoya University Graduate School of Science Division of Material Science Biophysics

About Nagoya University Graduate School of Science Division of Material Science Biophysics


Job title： Professor
Research field  (1)： Biophysics
Research keywords  (5)： Single-molecule measurement ,  Surface Science ,  Biophysics ,  Scanning Probe Microscopy ,  High-speed atomic force microscopy
Research theme for competitive and other funds  (41)：
  • 2021 - 2024 単一ゲル微粒子の強靭化に基づくミクロ空間移動科学の構築
  • 2021 - 2024 High-Speed-AFM Analysis of Structural and Mechanical Properties of Single Protein under Mechanical Stimulation
  • 2021 - 2023 Elucidation of working mechanisms of a molecular-engine complex responsible for protein membrane permeation by imaging of the conformational dynamics
  • 2020 - 2023 Study for the mechanism of functional expression and dysfunction of membrane proteins through direct observations of single molecular fluctuation
  • 2019 - 2023 再構成アプローチで解明するダイナミンの膜切断機構とその破綻に起因する疾患発症機序
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Papers (282)：
  • Saeko Yanaka, Atsuji Kodama, Shigetaka Nishiguchi, Rina Hiramine, Jiana Shen, Pornthip Boonsri, Duckyong Sung, Yukiko Isono, Hirokazu Yagi, Yohei Miyanoiri, et al. Identification of potential C1-binding sites in the immunoglobulin CL domains. International Immunology. 2024
  • Miki Kinoshita, Tohru Minamino, Takayuki Uchihashi, Keiichi Namba. FliH and FliI help FlhA bring strict order to flagellar protein export in Salmonella. Communications biology. 2024. 7. 1. 366-366
  • Saeko Yanaka, Hiroki Watanabe, Rina Yogo, Mesayamas Kongsema, Sachiko Kondo, Hirokazu Yagi, Takayuki Uchihashi, Koichi Kato. Quantitative Analysis of Therapeutic Antibody Interactions with Fcγ Receptors Using High-Speed Atomic Force Microscopy. Biological & pharmaceutical bulletin. 2024. 47. 1. 334-338
  • Kentaro Mannen, Takashi Nagata, Andrey Rozenberg, Masae Konno, María del Carmen Marín, Reza Bagherzadeh, Oded Béjà, Takayuki Uchihashi, Keiichi Inoue. Multiple roles of a conserved glutamate residue for unique biophysical properties in a new group of microbial rhodopsins homologous to TAT rhodopsin. Journal of Molecular Biology. 2023. 168331-168331
  • Carol Cho, Christian Ganser, Takayuki Uchihashi, Koichi Kato, Ji-Joon Song. Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication. Communications biology. 2023. 6. 1. 993-993
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MISC (78)：
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Patents (17)：
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Books (19)：
  • パリティ 2018年1月号
    丸善出版 2018
  • Compendium of Surface and Interface Analysis (The Surface Science Society of Japan, Eds)
    Springer 2018 ISBN:9789811061554
  • 光と生命の事典(真嶋哲郎, 七田芳則, 飯野盛利, 藤堂剛 編)
    朝倉書店 2016 ISBN:9784254171617
  • Noncontact Atomic Force Microscopy Vol.3 (Seizo Morita, Franz J. Giessibl, Ernst Meyer, Roland Wiesendanger, Eds)
    Springer 2015 ISBN:9783319155876
  • Atomic Force Microscopy in Nanobiology (Kunio Takeyasu Ed.)
    Pan Stanford Publishing 2014 ISBN:9789814411592
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Lectures and oral presentations  (47)：
  • Image Processing and Quantitative Analysis of High-Speed-AFM Data for Studying Single-Molecule Dynamics
    (第56回日本生物物理学会年会, Sympojium on "Multiple Approaches for Analyses of Protein Complexes -Methods and Applications" 2018)
  • 原子間力顕微鏡でリアルタイム可視化する生体/人工超分子の重合ダイナミクス
    (日本物理学会 2018年秋季大会 領域9, 5合同シンポジウム「時間分解プローブを駆使した表面・界面科学及び結晶成長の進展と展望 」 2018)
  • High-speed atomic force microscopy for direct visualization of biological macromolecules at work
    (The 79th Okazaki Conference "Synthetic, Biological, and Hybrid Molecular Engines" 2018)
  • 高速AFMの開発とタンパク質の動態計測
    (第58回生物物理若手の会 2018)
  • High-Speed Atomic Force Microscopy for Visualization and Manipulation of Biological and Artificial Molecules
    (SPMonSPM 2018 2018)
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Works (4)：
  • 高速AFMによる機能性材料の動的解析
    2007 -
  • Dynamic Analysis of Functional Materials using HIgh-speed AFM
    2007 -
  • 高速AFM法による膜タンパク質のダイナミクス計測
    2004 -
  • Dynamics of membrane proteins by high-speed AFM
    2004 -
Education (3)：
  • - 1998 Osaka University Graduate School, Division of Engineering
  • - 1995 Hiroshima University Graduate School, Division of Natural Science
  • - 1993 Hiroshima University Faculty of Science
Professional career (1)：
  • 工学 (大阪大学)
Work history (12)：
  • 2021 - 現在 Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research System
  • 2017/04 - 現在 Nagoya University Graduate School of Science, School of Science, Professor
  • 2017/04/01 - 現在 Nagoya University Division of Material Science(Physics), Graduate School of Science Professor
  • 2015/04/01 - 2017/03/31 Kanazawa University Bio-AFM Frontier Research Center, Institute of Science and Engineering Director
  • 2015/04/01 - 2017/03/31 Kanazawa University Institute of Science and Engineering Professor
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Committee career (4)：
  • 2015 - 現在 日本生物物理学会 理事
  • 2011 - 現在 日本生物物理学会 分野別専門委員会 委員
  • 2014 - 2015 日本生物物理学会 代議員
  • 2014 - 2015 日本生物物理学会 学会誌「生物物理」編集委員会 委員
Awards (6)：
  • 2013/04 - Ministry of Education, Culture, Sports , Science and Technology, Japan Education, Culture, Sports, Science Minister's Commendation Science and Technology Award of Science and Technology Development of High-Speed Atomic Force Microscopy
  • 2007/09 - The Japan Society of Applied Physics 29th JSAP Awards “High-Speed Atomic Force Microscopy for Studying the Dynamic Behavior of Protein Molecules at Work”, Jpn. J. Appl. Phys. Vol. 45, No. 3B, 2006, pp. 1897-1903
  • 2007 - Best Paper Award of the Japan Society of Applied Physics
  • 2005 - The KAO Foundation for Arts and Sciences, Research Grant
  • 2000/12 - Joint Reserach Center for Atom Technology JRCAT Special Awards Development of Fabrication Technique of Carbonnanotube Probe
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Association Membership(s) (9)：
THE PHYSICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  The Japan Society of Vacuum and Surface Science ,  日本生物物理学会 ,  THE JAPAN SOCIETY OF APPLIED PHYSICS ,  Japanese Surface Science Society ,  Japanese Biophysical Society ,  Japanese Applied Physics Society
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