Rchr
J-GLOBAL ID：200901085283977351   Update date: Sep. 25, 2024

Imamoto Naoko

イマモト ナオコ | Imamoto Naoko
Affiliation and department：
Jikei University of Health Care Sciences Graduate School of Medical Safety Management

About Jikei University of Health Care Sciences Graduate School of Medical Safety Management


Job title： Professor
Homepage URL  (1)： http://jnc.juhs.ac.jp
Research field  (1)： Cell biology
Research keywords  (7)： 分子シャペロン ,  Cell nucleus ,  stress réponse ,  nuclear pore complex ,  Hikeshi ,  Importin/exportin ,  nuclear transport
Research theme for competitive and other funds  (20)：
  • 2021 - 2024 Division of cellular function of nuclear transport pathways
  • 2018 - 2021 Analysis of function of Hikeshi affecting cellular homeostasis
  • 2015 - 2021 International research development of thermal biology
  • 2015 - 2020 temperature sensing of cell cyctoplasm and cell nucleus
  • 2014 - 2017 Analysis of Function and Mechanism of nuclear transport carrier Hikeshi
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Papers (131)：
  • Naoko Imamoto. Functional analysis of Hikeshi reveals physiological significance of nuclear Hsp70. Current opinion in cell biology. 2024. 91. 102426-102426
  • Shingo Kose, Sakie Yoshioka, Yutaka Ogawa, Ai Watanabe, Naoko Imamoto. The interaction between the import carrier Hikeshi and HSP70 is modulated by heat, facilitating the nuclear import of HSP70 under heat stress conditions. Genes to Cells. 2024. 29. 9. 782-791
  • Kayo Hibino, Yuji Sakai, Sachiko Tamura, Masatoshi Takagi, Katsuhiko Minami, Toyoaki Natsume, Masa A Shimazoe, Masato T Kanemaki, Naoko Imamoto, Kazuhiro Maeshima. Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes. Nature communications. 2024. 15. 1. 7152-7152
  • Tomoko Funakoshi, Naoko Imamoto. Reconstitution of nuclear envelope subdomain formation on mitotic chromosomes in semi-intact cells. Cell structure and function. 2024. 49. 2. 31-46
  • Shingo Kose, Yutaka Ogawa, Naoko Imamoto. Thermal Stress and Nuclear Transport. Advances in experimental medicine and biology. 2024. 1461. 61-78
ｍore...
MISC (65)：
  • Imamoto, N, Larson D. Editorial overview: Cell nucleus. Curr. Opin. Cell Biol. 2019. 58. iii-iv
  • Naoko Imamoto. Regulating β-Catenin Nuclear Import with the Small GTPase Rap. Developmental Cell. 2018. 44. 2. 135-136
  • 三村恭弘, 竹本智子, 横田秀夫, 今本尚子. 核膜サブドメインPore-free islandは核膜孔形成によって偏縁から消失する. 日本細胞生物学会大会(Web). 2016. 68th. ROMBUNNO.P2-6 (WEB ONLY)-87
  • 三村恭弘, 竹本智子, 横田秀夫, 今本尚子. 間期の核膜孔複合体形成と核膜サブドメインPore-free islandの消失. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th. ROMBUNNO.1PS12-4 (WEB ONLY)
  • Kose, S, Funakoshi, T, Imamoto, N. Reconstitution of nucleocytoplasmic transport using digitonin-permeabilized cells. Methods Mol. Biol. 2015. 1262. 291-303
ｍore...
Lectures and oral presentations  (42)：
  • Analysis of Function of Hikeshi
    (NT19 Nucleocytoplasmic Transport Airlie meeting 2019)
  • Importinαファミリーによる温度依存的な核-細胞質間輸送制御
    (第71 回 日本細胞生物学会 シンポジウム”温度生物学:温度センシングと細胞機能” 2019)
  • 分子シャペロンHsp70の核内輸送運搬体Hikeshi:その輸送機構と生理機能について
    (第41回日本分子生物学会年会 ワークショップ 2018)
  • 核-細胞質間輸送運搬体とHikeshiの機能
    (“エピゲノム解析を基盤とするがん化と老化関連疾患の治療戦略”山口大学研究拠点セミナー 2018)
  • 熱ショックタンパク質Hsp70の核内輸送を担う輸送運搬体Hikeshiの機能
    (第91回 日本生化学会 シンポジウム“ストレス応答によりプロテオスタシス制御の新展開” 2018)
ｍore...
Works (4)：
  • Identification of Hikeshi
    2012 -
  • Analysis of interphase nuclear pore complex assembly
    2010 -
  • Cell cycle dynamics of nuclear pores
    2007 -
  • Identification of Importin alpha/beta
    1995 -
Education (3)：
  • 1984 - 1988 Osaka University Institute for Molecular and Cellular Biology Ph.D. in medicine
  • 1982 - 1984 Osaka University Institute for Molecular and Cellular Biology Master of medical science
  • 1978 - 1982 Osaka University Faculty of Science Biology
Professional career (1)：
  • 医学博士
Work history (9)：
  • 2024/04 - 現在 Jikei University of Health Care Sciences Graduate School of Medical Safety Management Professor
  • 2008/04 - 2024/03 Yokohama City University Visiting Professor
  • 2004/04 - 2024/03 Saiyama University Visiting Professor
  • 2002/04 - 2024/03 RIKEN Cellular Dynamics Laboratory Chief Scientist
  • 2000/05 - 2002/03 National Institute of Genetics Associate Professor
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Committee career (16)：
  • 2019/06 - 現在 CREST 多細胞領域アドバイザー
  • 2019/04 - 現在 臨床ストレス応答学会 幹事
  • 2018 - 現在 日本生化学会 代議員
  • 2007 - 現在 日本生化学会 評議員
  • 1995 - 現在 日本細胞生物学会 評議員
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Awards (3)：
  • 2014 - Mitsubishi Science Foundation
  • 2013 - Significant Achievement Award from RIKEN
  • 1996 - Yong Investigator Award from Biochemical Society
Association Membership(s) (5)：
The American Society for Cell Biology ,  Japan Society of Biochemistry ,  Japan Society of Molecular Biology ,  Japan Society of Cell Biology ,  The Biomedical Society for Stress Response
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