Art

J-GLOBAL ID：200902208217946346   Reference number：03A0222949

In Vitro Antimalarial Activities of the Microbial Metabolites.

微生物代謝産物のin vitro抗マラリア活性

Author (9)： OTOGURO K (Kitasato Inst., Tokyo, JPN) ,  UI H (Kitasato Univ., Tokyo, JPN) ,  ISHIYAMA A (Kitasato Inst., Tokyo, JPN) ,  ARAI N (Kitasato Univ., Tokyo, JPN) ,  KOBAYASHI M (Kitasato Inst., Tokyo, JPN) ,  TAKAHASHI Y (Kitasato Univ., Tokyo, JPN) ,  MASUMA R (Kitasato Univ., Tokyo, JPN) ,  YAMADA H (Kitasato Univ., Tokyo, JPN) ,  OMURA S (Kitasato Univ., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 56  Issue： 3  Page： 322-324  Publication year： Mar. 25, 2003 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： in vitro experiment ,...
Semi thesaurus term： FKI-0266 ,...

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JST classification (2)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Basic research of antiprotozoan drugs and anthelmintics  (GW17080G)

Substance index (3)： Leucinostatin A ,  Polyketomycin ,  Takaokamycin

Reference (14)：

• 1) OTOGURO, K.; A. KOHANA, C. MANABE, A. ISHIYAMA, H. UI, K. SIOMI, H. YAMADA & S. OMURA: Potent antimalarial activities of polyether antibiotic, X-206. J. Antibiotics 54: 658-663, 2001
• 2) OTOGURO, K.; A. ISHIYAMA, H. UI, M. KOBAYASHI, C. MANABE, G. YAN, Y. TAKAHASHI, H. TANAKA, H. YAMADA & S. OMURA: In vitro and in vivo antimalarial activities of the monoglycoside polyether antibiotic, K-41 against drug resistant strains of Plasmodia. J. Antibiotics 55: 832-834, 2002
• 3) MORI, Y.; M. TSUBOI, M. SUZUKI, K. FUKUSHIMA & T. ARAI: Isolation of leucinostatin A and one of its constituents, the new amino acid, 4-methyl-6-(2-oxobutyl)-2-piperidinecarboxylic acid, from Paecilomyces lilacinus A-267. J. Antibiotics 35: 543-544, 1982
• 4) MOMOSE, I.; W. CHEN, H. NAKAMURA, H. NAGANAWA, H. IINUMA & T. TAKEUCHI: Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination. J. Antibiotics 51: 26-32, 1998
• 5) OMURA, S.; H. MAMADA, N-J. WANG, N. IMAMURA, R. OIWA, Y. IWAI & N. MUTO: Takaokamycin, a new peptide antibiotic produced by Streptomyces sp. J. Antibiotics 37: 700-705, 1984

Terms in the title (2)： 微生物代謝産物 ,  抗マラリア活性