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J-GLOBAL ID：200902237885474979   Reference number：08A0183157

Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube

多層カーボンナノチューブの腹腔内適用によるp53+/-マウスにおける中皮腫の誘発

Author (8)： TAKAGI Atsuya (Div. of Cellular and Molecular Toxicology, Biological Safety Res. Center, National Inst. of Health Sciences) ,  HIROSE Akihiko (Div. of Risk Assessment, Biological Safety Res. Center, National Inst. of Health Sciences) ,  NISHIMURA Tetsuji (Div. of Environmental Chemistry, National Inst. of Health Sciences) ,  FUKUMORI Nobutaka (Dep. of Environmental Health and Toxicology, Tokyo Metropolitan Inst. of Public Health) ,  OGATA Akio (Dep. of Environmental Health and Toxicology, Tokyo Metropolitan Inst. of Public Health) ,  OHASHI Norio (Dep. of Environmental Health and Toxicology, Tokyo Metropolitan Inst. of Public Health) ,  KITAJIMA Satoshi (Div. of Cellular and Molecular Toxicology, Biological Safety Res. Center, National Inst. of Health Sciences) ,  KANNO Jun (Div. of Cellular and Molecular Toxicology, Biological Safety Res. Center, National Inst. of Health Sciences)
Material： Journal of Toxicological Sciences  (日本毒性学会学術年会プログラム・要旨集)
Volume： 33  Issue： 1  Page： 105-116 (J-STAGE)  Publication year： 2008 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Mesothelioma ,...
Semi thesaurus term： asbestos ,...

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JST classification (4)： Carbon and its compounds  (YB02060D) ,  Tumors(=neoplasms)of musculoskeletal system  (GG04000A) ,  Other setting materials  (YC05070M) ,  Carcinogenic mechanisms and factors  (GE02020C)

Reference (22)：

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• Coussens, L.M. and Werb, Z. (2002): Inflammation and cancer. Nature, 420, 860-867.
• Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G. and Alexander, A. (2006): Carbon nanotubes: A review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol. Sci., 92, 5-22.
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• Hei, T.K., Xu, A., Huang, S.X. and Zhao, Y. (2006): Mechanism of fiber carcinogenesis: From reactive radical species to silencing of the beta igH3 gene. Inhal. Toxicol., 18, 985-990.

Terms in the title (5)： 多層カーボンナノチューブ ,  腹腔 ,  マウス ,  中皮腫 ,  誘発