Molecular Structural and Functional Characterization of Tumor Suppressive Anti-ErbB-2 Monoclonal Antibody by Phage Display System.

ITOH K; INOUE K; TEZUKA T; TADA H; HASHIMOTO Y; MASUKO T; SUZUKI T

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J-GLOBAL ID：200902243168122928 Reference number：03A0199710

Molecular Structural and Functional Characterization of Tumor Suppressive Anti-ErbB-2 Monoclonal Antibody by Phage Display System.

ファージディスプレイ系による腫よう抑制抗ErbB-2モノクローナル抗体の分子構造及び機能特性化

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Material：
Volume： 133 Issue： 2 Page： 239-245 Publication year： Feb. 01, 2003
JST Material Number： F0286A ISSN： 0021-924X CODEN： JOBIAO Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Biochemistry of antigens,antibodies,complements , Basic research of antitumor(=antineoplastic)drugs

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TIWARI, R. K. HER2/neu amplification and over-expression in primary human breast cancer is associated with early metastasis. Anticancer Res. 1992, 12, 419-425
HUDZIAK, R. M. p185/HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol. Cell. Biol. 1989, 9, 1165-1172
STYLES, J. M. Rat monoclonal antibodies to the extracellular domain of the product of the c-erbB-2 proto-oncogene. Int. J. Cancer. 1990, 45, 320-324

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