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J-GLOBAL ID：201002224891836102   Reference number：10A0365116

Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1α and reduces HIF-1α level in ACHN human renal adenocarcinoma cells

ヒト腎腺癌細胞ACHNにおいて主要ボルトタンパク質は低酸素誘導因子(HIF)-1αと複合体を形成しHIF-1αレベルを低下させる

Author (8)： IWASHITA Ken-ichi (Kagoshima Univ., Kagoshima) ,  IKEDA Ryuji (Kagoshima Univ., Kagoshima) ,  TAKEDA Yasuo (Kagoshima Univ., Kagoshima) ,  SUMIZAWA Tomoyuki (Univ. Occupational and Environmental Health, Kitakyushu) ,  FURUKAWA Tatsuhiko (Kagoshima Univ., Kagoshima, JPN) ,  YAMAGUCHI Tatsuya (Kagoshima Univ., Kagoshima) ,  AKIYAMA Shin-ichi (Kagoshima Univ., Kagoshima, JPN) ,  YAMADA Katsushi (Kagoshima Univ., Kagoshima)
Material： Cancer Science  (Cancer Sci)
Volume： 101  Issue： 4  Page： 920-926  Publication year： Apr. 2010 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： HIF-1 alpha ,...

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JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S)

Reference (38)：

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• VASU, SK. cDNA cloning and disruption of the major vault protein α gene (mvpA) in Dictyostelium discoideum. J Biol Chem. 1993, 268, 15356-15360
• KICKHOEFER, VA. The sequence of a cDNA encoding the major vault protein from Rattus norvegicus. Gene. 1994, 151, 257-260
• KICKHOEFER, VA. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase. J Cell Biol. 1999, 146, 917-928
• KICKHOEFER, VA. Vaults and telomerase share a common subunit, TEP1. J Biol Chem. 1999, 274, 32712-32717

Terms in the title (9)： ヒト ,  腎腺癌 ,  細胞 ,  ボルト ,  タンパク質 ,  低酸素誘導因子 ,  HIF ,  複合体 ,  HIF-1α