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Activated protein C resistance in the Japanese population due to homozygosity for the factor V R2 haplotype
About OKADA Hiromi
About Nagoya Medical Center, Nagoya, JPN
About OKADA Hiromi
About Nagoya City Univ., Nagoya, JPN
About TOYODA Yoshimi
About Nagoya Univ. School of Health Sci., Nagoya, JPN
About TAKAGI Akira
About Nagoya Univ. School of Health Sci., Nagoya, JPN
About SAITO Hidehiko
About Nagoya Central Hospital, Nagoya, JPN
About KOJIMA Tetsuhito
About Nagoya Univ. School of Health Sci., Nagoya, JPN
About YAMAZAKI Tomio
About Nagoya Medical Center, Nagoya, JPN
Material：
About International Journal of Hematology
Volume： 91 Issue： 3 Page： 549-550 Publication year： Apr. 2010
JST Material Number： F0888A ISSN： 0925-5710 CODEN： IJHEEY Document type： Article
Article type： 短報 Country of issue： Germany, Federal Republic of (DEU) Language： ENGLISH (EN)
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About blood coagulation disorder
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Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
About R2ハプロタイプ
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Category name(code) classified by JST.
About Basic hematology
About Genetic variation
- DAHLBACK, B. Procoagulant and anticoagulant properties of coagulation factor V : factor V Leiden (APC resistance) causes hypercoagulability by dual mechanisms. J Lab Clin Med. 1999, 133, 415-422
- BERNARDI, F. A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype. Blood. 1997, 90, 1552-1557
- DE VISSER, MCH. The HR2 haplotype of factor V : effects on factor V levels, normalized activated protein C sensitivity ratios and the risk of venous thrombosis. Thromb Haemost. 2000, 83, 577-582
- BRUGGE, J. Functional characterization of recombinant factor V molecules mimicking the R2-haplotype. XIXth congress of the International Society on Thrombosis and Haemostasis, Birmingham, England
- DAHLBACK, B. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C : prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA. 1993, 90, 1004-1008
Keywords automatically extracted from the title.
About 第V因子
About ハプロタイプ
About ホモ接合
About 日本人
About 集団
About 活性化蛋白質C抵抗性
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