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J-GLOBAL ID：201201003646554562 Update date: Mar. 06, 2025

Nagai-Okatani Chiaki

オカタニチアキ | Nagai-Okatani Chiaki

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Affiliation and department：
Job title： Senior Researcher
Homepage URL (2)： https://unit.aist.go.jp/cmb5/ja/group/1-9Group.html , https://unit.aist.go.jp/cmb5/en/group/1-9Group.html

Research keywords (6)：組織糖鎖イメージング , Glycoproteomics , Glycobiology , 心不全 , biologically active peptide , Bioorganic chemistry

Research theme for competitive and other funds (8)：

2024 - 2027 糖鎖マルチオミクス解析を駆使した心筋線維化の可視化と分子メカニズムの解明
2020 - 2023 心筋線維化の評価・治療のための糖鎖マーカー開発を目指したグライコプロテオミクス
2017 - 2020 Comparative glycoproteomics for elucidating molecular mechanism of cardiac hypertrophy
2017 - 2018 拡張型心筋症に関連する糖鎖変化の同定と新規血液マーカーへの応用
2015 - 2017 Development of a method to analyze glycosylation site-specific glycome at proteome-scale for study on significance of glycan heterogeneity

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Papers (43)：

Shunsuke Tomita*, Chiaki Nagai-Okatani*. Expanding the recognition of monosaccharides and glycans: A comprehensive analytical approach using chemical-nose/tongue technology and a comparison to lectin microarrays. BBA Advances. 2025. 7. 100129-100129
Chiaki Nagai-Okatani*, Azusa Tomioka, Daisuke Tominaga, Hiroaki Sakaue, Atsushi Kuno, Hiroyuki Kaji*. Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray. Analytical and bioanalytical chemistry. 2024
Chiaki Nagai-Okatani#*, Daisuke Tominaga#, Azusa Tomioka#, Hiroaki Sakaue, Norio Goda, Shigeru Ko, Atsushi Kuno, Hiroyuki Kaji*. GRable version 1.0: A software tool for site-specific glycoform analysis with improved MS1-based glycopeptide detection with parallel clustering and confidence evaluation with MS2 information. Molecular & cellular proteomics : MCP. 2024. 100833-100833
Chiaki Nagai-Okatani#*, Daisuke Tominaga#, Azusa Tomioka#, Hiroaki Sakaue, Norio Goda, Shigeru Ko, Atsushi Kuno, Hiroyuki Kaji*. GRable version 1.0: A software tool for site-specific glycoform analysis using the improved Glyco-RIDGE method with parallel clustering and MS2 information. bioRxiv. 2023
Patcharaporn Boottanun*, Chiaki Nagai-Okatani*#, Misugi Nagai, Umbhorn Ungkulpasvich, Shinjiro Yamane, Masao Yamada, Atsushi Kuno#. An improved evanescent fluorescence scanner suitable for high-resolution glycome mapping of formalin-fixed paraffin-embedded tissue sections. Analytical and bioanalytical chemistry. 2023

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MISC (87)：

BOOTTANUN Patcharaporn, 岡谷千晶, 川西邦夫, 川西邦夫, 馬場正樹, 中務智文, 石津智子, 山田雅雄, 久野敦. Spatially Different Alterations of N- and O-Glycosylations in Cardiac Fibrosis of Rat Hearts with Hypertensive Heart Failure. 日本糖質学会年会要旨集. 2024. 43rd
岡谷千晶, 藤田典昭, BOOTTANUN Patcharapon, BOOTTANUN Patcharapon, 田中美雪, 塩田正明, 新町大輔, 安形清彦, 安形清彦, 木下聖子, et al. LM-GlycoRepo Ver.1.0: a novel repository system for lectin microarray-based mouse tissue glycome mapping data. 日本糖質学会年会要旨集. 2024. 43rd
川西邦夫, 川西邦夫, DANGCAO Thuylinh, 沖田結花里, 渡邊幸秀, 橋本幸枝, HENGPHASATPORN Kowit, 岡谷千晶, 木村隆治, 白谷理恵, et al. Tumor Immunoregulatory Mechanisms by Nonmetastatic Melanoma Protein B in Triple Negative Breast Cancer. 日本癌学会学術総会抄録集(Web). 2024. 83rd
岡谷千晶, 富岡あづさ, 富永大介, 富永大介, 坂上弘明, 久野敦, 梶裕之, 梶裕之. Glyco-RIDGE-based site-specific glycoform analysis of glycoproteins: Development of a novel web tool named “GRable” and application to large-scale analysis of mouse tissues. 質量分析総合討論会講演要旨集. 2024. 72nd
岡谷千晶, 堀内梅子, BOOTTANUN Patcharaporn, 久野敦. Lectin-assisted imaging mass cytometry: single-cell-level bilateral imaging of proteins and glycans for spatial analysis of protein glycosylations. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)

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Patents (1)：

β-ANPによる心不全の検出方法

Books (1)：

脱皮と変態の生物学-昆虫と甲殻類のホルモン作用の謎を追う(19章)
東海大学出版会 2011 ISBN:4486019040

Education (5)：

2009 - 2012 東京大学大学院農学生命科学研究科応用生命化学専攻博士後期課程
2007 - 2009 東京大学大学院農学生命科学研究科応用生命化学専攻修士課程
2005 - 2007 The University of Tokyo
2003 - 2005 東京大学理科二類
2000 - 2003 富山県立富山中部高等学校

Professional career (1)：

Doctorate of Agriculture (The University of Tokyo)

Work history (6)：

2020/10 - 現在 National Institute of Advanced Industrial Science and Technology Molecular and Cellular Glycoproteomics Research Group Senior Researcher
2022/08 - 2023/07 National Institute of Advanced Industrial Science and Technology
2020/04 - 2020/09 National Institute of Advanced Industrial Science and Technology Molecular and Cellular Glycoproteomics Research Group Researcher
2015/04 - 2020/03 National Institute of Advanced Industrial Science and Technology Biotechnology Research Institute for Drug Discovery Researcher (tenure-track position)
2012/04 - 2015/03 National Cerebral and Cardiovascular Center Departement of Molecular Pharmacology Postdoctral researcher

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Awards (2)：

2019 - 日本農芸化学会農芸化学若手女性研究者賞
2016/07 - 日本プロテオーム学会2016年大会若手優秀発表賞

Association Membership(s) (4)：

JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , Japan Human Proteome Organisation , THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , THE JAPANESE CIRCULATION SOCIETY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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